Reviews

2018

“A New Family of Sesterterpenoids Isolated Around The Pacific Rim” H. J. Shirley, M. L. Jamieson, M. A. Brimble and C. D. Bray, Natural Product Reports, 2018, 35, 210-219.

Invited Review

2017

“Synthesis of Enediamino Amino Acid Analogues and Peptides”
S. Zhang, L. M. De Leon Rodriguez, P. W. R. Harris and M. A. Brimble,
Asian Journal of Organic Chemistry, 2017, 6, 1180-1190.
http://doi.org/10.1002/ajoc.201700169

Invited Review for Special Issue for Editorial Advisory Board Members

“Synthesis of AHMOD-Containing Aminolipopeptides, Unique Bioactive Peptaibiotics”
L. A. Stubbing, I. Kavianinia and M. A. Brimble,
Organic and Biomolecular Chemistry201715, 3542-3549.
http://doi.org/10.1039/c7ob00541e

“Gold Catalysis: Synthesis of Spiro, Bridged, and Fused Ketal Natural Products”
R. Quach, D. P. Furkert and M. A. Brimble,
Organic and Biomolecular Chemistry, 2017, 15, 3098-3104.
http://doi.org/10.1039/c7ob00496f

Front Cover and Invited Review

“Gaq Proteins: Molecular Pharmacology and Therapeutic Potential”
D. Kamato, P. Mitra, F. Davis, N. Osman, R. Chaplin, P. J. Cabot, R. Afroz, W. Thomas, W. Zheng, H. Kaur, M. A. Brimble and P. J. Little,
Cell and Molecular Life Sciences201774, 1379-1390.  
http://doi.org/10.1007/s00018-016-2405-9

“Pyranonaphthoquinones – Isolation, Biology and Synthesis: An Update”
B. J. Naysmith, P. A. Hume, J. Sperry and M. A. Brimble,
Natural Product Reports201734, 25-61. 
http://doi.org/10.1039/c6np00080k

2016

“Enduracididine, a Rare Amino Acid Component of Peptide Antibiotics: Natural Products and Synthesis”
D. J. Atkinson, B. J. Naysmith, D. P. Furkert amd M. A. Brimble,
Beilstein Journal of Organic Chemistry, 2016, 12, 2325-2342.

Open Access: http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-12-226

Invited Review

“Chemical Synthesis of Peptides Containing Site-Specific Advanced Glycation Endproducts”
H. Kaur, M. Kamalov and M. A. Brimble,
Accounts of Chemical Research, 2016, 49, 2199-2208.
http://doi.org/10.1021/acs.accounts.6b00366

Invited Review

“Structure–Mechanical Property Correlations of Hydrogel Forming beta-Sheet Peptides”
L. M. De Leon Rodriguez, Y. Hemar, J. Cornish and M. A. Brimble,
Chemical Society Reviews201645, 4797-4824.
http://doi.org/10.1039/c5cs00941c

“Short Anabolic Peptides for Bone Growth”
Z. Amso, J. Cornish and M. A. Brimble,
Medicinal Research Reviews201636, 579-640.
http://doi.org/10.1002/med.21388

“Nitropyrrole Natural Products: Isolation, Biosynthesis and Total Synthesis”
X.-B. Ding, M. A. Brimble and D. P. Furkert,
Organic and Biomolecular Chemistry201614, 5390-5401.
http://doi.org/10.1039/c5ob02599k

“Intermolecular Peptide Cross-Linking by Using Diaminodicarboxylic Acids”
M. Kamalov, H. Kaur and M. A. Brimble,
Chemistry – A  European Journal, 2016, 22, 3622-3631.
http://doi.org/10.1002/chem.201503458

Front Cover and Invited Review for Special Issue “Women in Chemistry” to celebrate International Women’s Day 2016.

“Synthesis and Bioactivity of Antitubercular Peptides and Peptidomimetics: An Update”
L. M. De Leon Rodriguez, H. Kaur and M. A. Brimble,
Organic and Biomolecular Chemistry201614, 1177-1187.
http://doi.org/10.1039/c5ob02298c

2015

“Isolation, Biological Activity, Biosynthesis and Synthetic Studies Towards the Rubromycin Family of Natural Products”
D. J. Atkinson and M. A. Brimble,
Natural Product Reports201532, 811-840.

“An Update on New Methods to Synthesize Cyclotetrapeptides”
L. M. De Leon Rodriguez, A. J. Weidkamp and M. A. Brimble,
Organic and Biomolecular Chemistry201513, 6906-6921.

“Structure, Function, Pharmacology and Therapeutic Potential of the G Protein, Gα/q,11”
D. Kamato, L. Thach, R. Bernard, V. Chan, W. Zheng, H. Kaur, M. A. Brimble, N. Osman and P. J. Little,
Frontiers in Cardiovascular Medicine20152, 1-11.

“The Role for IGF-1-derived Small Neuropeptides as a Therapeutic Target for Neurological Disorders”
J. Guan, P. W. R. Harris, M. A. Brimble, Y. Lei, J. Lu, Y. Yang and A. J. Gunn,
Expert Opinion on Therapeutic Targets201519, 785-793.

“A Review of the Synthesis of alpha-Carbolines”
A. D. Wadsworth, B. J. Naysmith and M. A. Brimble,
European Journal of Medicinal Chemistry201597, 816-829.

“Glucose as an Agent of Post-Translational Modification in Diabetes – New Cardiac Epigenetic Insights”
K. M. Mellor, M. A. Brimble and L. M. D. Delbridge,
Life Sciences2015129, 48-53.

2014

“Enhancing the Oral Bioavailability of Peptide Drugs by using Chemical Modification and Other Approaches”
N. Yin, M. A. Brimble, P. W. R. Harris and J. Wen,
Medicinal Chemistry20144, 763-769.

“Recent Developments in Transition Metal-Catalysed Spiroketalisation”
R. Quach, D. F. Chorley and M. A. Brimble,
Organic and Biomolecular Chemistry, 2014, 12, 7423-7432.

Invited review

“C–H Functionalization in the Synthesis of Amino Acids and Peptides”
A. Noisier and M. A. Brimble,
Chemical Reviews, 2014, 114, 8775-8806.

Open access: http://pubs.acs.org/doi/abs/10.1021/cr500200x

Invited review

2013

N-Alkylsulfonylimines as Dipolarophiles in Cycloaddition Reactions”
L. A. Stubbing, G. P. Savage and M. A. Brimble,
Chemistry – An Asian Journal20138, 42-48.

“Rules for the Abbreviation of Protecting Groups”
M. A. Brimble, D. StC. Black, R. Hartshorn, A. P. Rauter, C.-K. Sha and L. V. Sydnes,
Pure and Applied Chemistry, 2013, 85, 307-313.

IUPAC technical report

2012

“Synthetic Approaches to [5,6]-Benzannulated Spiroketal Natural Products” 
M. C. McLeod, M. A. Brimble, D. C. K. Rathwell, Z. E. Wilson and T.-Y. Yuen,
Pure and Applied Chemistry201284, 1379-1390.

“Synthesis of Glycosylated 5-Hydroxylysine, an Important Amino acid present in Collagen-like Proteins such as Adiponectin”
K. R. Herbert, G. M. Williams, G. J. S. Cooper and M. A. Brimble,
Organic and Biomolecular Chemistry201210, 1137-1144.

“The Kulinkovich Hydroxycyclopropanation Natural Product Synthesis”
I. Haym and M. A. Brimble,
Organic and Biomolecular Chemistry, 2012, 10, 7649-7665.

Invited review – selected for front cover

2011

“Synthetic Studies Towards the Spiroimine Unit of the Spirolides”  
S. Gueret and M. A. Brimble,
Pure and Applied Chemistry201183, 425-433.

“Natural Products Targeting Telomere Maintenance”  
J. L.-Y. Chen, J. Sperry, N. Y. Ip and M. A. Brimble,
MedChemComm, 2011, 2, 229-245.

Invited review for inaugural issue

“Synthesis of Dehydrotryptophan and Dehydrotrytophan-Containing Peptides”
H. Kaur, A. Heapy and M. A. Brimble,
Organic and Biomolecular Chemistry, 2011, 9, 5897-5907.

Highlighted on the Organic and Biomolecular Chemistry blog at http://blogs.rsc.org/ob/ and promoted through the OBC twitter account http://twitter.com/OrgBiomolChem

2010

“Synthesis of Natural Products Containing Spiroketals via Intramolecular Hydrogen Abstraction”
J. Sperry, Y.-C. Liu and M. A. Brimble,
Organic and Biomolecular Chemistry, 2010, 8, 29-38.

Invited review and top 10 downloaded articles

“Methyltrichlorosilane, CAS No: 75-79-6 Update”
M. A. Brimble,
in Electronic Encyclopedia of Reagents for Organic Synthesis [e-EROS], eds. L. A. Paquette, D. Crich, P. L. Fuchs and P. Wipf, John Wiley & Sons Inc., 2010

“Isolation, Biological Activity and Synthesis of Benzannulated Spiroketal Natural Products”
J. Sperry, Z. E. Wilson, D. C. K. Rathwell and M. A. Brimble,
Natural Product Reports, 2010, 27, 1117-1137. 

Invited review – for a thematic series “Synthetic Natural Product Chemistry”

“Spiroimine Shellfish Poisoning (SSP) and the Spirolide Family of Shellfish Toxins: Isolation, Structure, Biological Activity and Synthesis”
S. Guéret and M. A. Brimble,
Natural Product Reports201027, 1350-1366.

“Synthesis of Neoglycopeptides via Click Chemistry”
N. Miller, G. M. Williams and M. A. Brimble,
International Journal of Peptide Research and Therapeutics, 2010, 16, 125-132.

Invited review

2009

“Molecules Derived from the Extremes of Life”
Z. E. Wilson and M. A. Brimble,
Natural Product Reports, 2009, 26, 44-71.

Invited review – selected for front cover, also featured in “Extreme Potentials” Chemistry World, 2011, 8(6), 48-51.

2008

“Pyranonaphthoquinones—Isolation, Biological Activity and Synthesis”
J. Sperry, P. Bachu and M. A. Brimble,
Natural Product Reports, 2008, 25, 376-400.

Invited review – selected for inclusion in Chemical Biology, 2008, issue 5

“Instant Insight: Life at the Extremes”
Z. E. Wilson and M. A. Brimble,
Chemistry World20085, B95.

2007

“Synthetic Studies Towards Shellfish Toxins Containing Spiroacetal Units”
M. A. Brimble and R. Halim  
Pure and Applied Chemistry200779, 153-162.

“Synthesis of Macrocyclic Shellfish Toxins Containing Spiroimine Moieties”
P. D. O’Connor and M. A. Brimble,
Natural Product Reports, 2007, 24, 869-885.

Invited review

“Use of Stabilized Phthalide Anion Annulation Reactions in Synthesis: An Update”
K. Rathwell and M. A. Brimble,
Synthesis, 2007, 643-662.

Invited review

“2-Trimethylsilyloxyfuran, CAS No: 61550-02- Update”
J. Sperry and M. A. Brimble,
in Electronic Encyclopedia of Reagents for Organic Synthesis [e-EROS], eds. L. A. Paquette, D. Crich, P. L. Fuchs and P. Wipf, John Wiley & Sons Inc., 2007.

2006

“A Review of Advances in the Synthesis of Analogues of the Delphinium Alkaloid Methyllycaconitine”
K. J. Goodall, D. Barker and M. A. Brimble,
Synlett2005, 1809-1827.

“A Review of Agents Patented for their Neuroprotective Properties”
M. A. Brimble and M. S. Levi,
Recent Patents in CNS Drug Discovery20061, 139-146.

“Synthetic Studies Towards the Pectenotoxins: A Review”
M. A. Brimble and R. Halim,
Organic and Biomolecular Chemistry20064, 4048-4058.

2004

“A Review of Neuroprotective Agents”
M. A. Brimble and M. S. Levi,
Current Medicinal Chemistry200411, 2383-2398.

2003

“Chemistry of Bis-Spiroacetal Systems: Natural Products, Synthesis and Stereochemistry”
M. A. Brimble and D. P. Furkert,
Current Organic Chemistry20037, 1461-1484.

“Polyether Antibiotics”
M. A. Brimble,
in Kirk-Othmer Encyclopedia of Chemical Technology Online Edition, ed. A. Seidel,  John Wiley & Sons, Inc., 2003.

2001

“Di-(–)-(1R,2S)-2-phenyl-1-cyclohexyl Diazenedicarboxylate”
M. A. Brimble,
in Electronic Encyclopedia of Reagents for Organic Synthesis [e-EROS], eds L. A. Paquette, D. Crich, P. L. Fuchs and P. Wipf, John Wiley and Sons Inc., 2001.

2000

“Synthetic Strategies Towards Pyranonaphthoquinone Antibiotics”
M. A. Brimble, M. R. Nairn and H. Prabaharan,
Tetrahedron200056, 1937-1992.

“Synthetic Strategies Towards Pyranonaphthoquinone Antibiotics”
M. A. Brimble,
Pure and Applied Chemistry200072, 1635-1639.

1999

“Pyranonaphthoquinone Antibiotics – Isolation, Structure and Biological Activity”
M. A. Brimble,  L. J. Duncalf and M. R. Nairn,
Natural Product Reports199916, 267-281.

“Synthesis of Bis-Spiroacetal Ring Systems”
M. A. Brimble and F. A. Fares,
Tetrahedron199955, 7661-7706.

“Synthetic Studies Towards Natural Products Containing Bis-Spiroacetals”
M. A. Brimble,
Journal of Heterocyclic Chemistry199936, 1373-1389.

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