Distinguished Professor Margaret Brimble

CNZM, FRSNZ, FRSC, FRACI, FNZIC

Chair of Organic and Director of Medicinal Chemistry, School of Chemical Sciences and School of Biological Sciences

Principal Investigator of Maurice Wilkins Centre for Molecular Biodiscovery

Principal Investigator of Brain Research New Zealand

Associate Investigator of MacDiarmid Institute

 

Key Skills and Expertise

Organic Synthesis; Natural Products Synthesis;
Asymmetric Synthesis; Organocatalysis;
Medicinal Chemistry; Drug Development;
Agrochemicals;
Synthesis of Peptide and Peptidomimetics;
Synthsis of Glycopeptide, Phosphopeptides and Lipopeptides;
Synthsis of neo-Glycopeptides, neo-Phosphopeptides and neo-Lipopeptides using Click Chemistry and Olefin Metathesis;
cGMP Peptides as Vaccine Components;
Synthesis of Small Proteins, Glycopolymers and Hydrogels;
Consultant for Pharmaceutical Industry;
Expert Witness for Litigation (Pharmaceuticals).

Academic Qualifications

1983 to 1985
PhD in Chemistry, The University of Southampton, UK
1982 to 1983
MSc in Chemistry with First Class Honours, The University of Auckland, NZ
1979 to 1981
BSc in Chemistry, The University of Auckland, NZ

Appointments

2014 to 2018
Visiting Professor, School of Life Sciences, University of Sussex, UK
2013 Associate Investigator, MacDiarmid Institute, NZ
2013 Principal Investigator, New Zealand Brain Research Institute
2012 Distinguished Professor, The University of Auckland, NZ
2010 Associate Investigator, Centre for Brain Research, The University of Auckland, NZ
2004 Principal Investigator and Member of Management Committee, Maurice Wilkins Centre for Molecular Biodiscovery (MWC), a Centre of Research Excellence (CoRE)
2002 Director of Medicinal Chemistry, The University of Auckland, NZ
2013 Interim Head of School, School of Chemical Sciences, The University of Auckland, NZ
2009 Adjunct Professor, La Trobe University, Australia
2008 Distinguished Visiting Research Fellow, Victorian Institute of Chemical Sciences, Australia
2001 to 2009
Head of Medicinal Chemistry, Neuren Pharmaceuticals Ltd., NZ
1999 to 2011
Professor and Chair of Organic Chemistry, The University of Auckland, NZ
1995 to 1997
Senior Lecturer/Reader in Organic Chemistry, The University of Sydney, Australia
1993 to 1994
Senior Lecturer in Chemistry, The University of Auckland, NZ
1992 Invited Visiting Professor, University of California, Berkeley, USA
1986 to 1992
Lecturer in Chemistry, Massey University, Palmerston North, NZ

Fellowship and Honours

2012 Queen’s Honour - Companion of the New Zealand Order of Merit for Service to Science (CNZM)
2005 Fellow of the Royal Society of Chemistry, UK (FRSC)
2004 Queen's Honour - Member New Zealand Order of Merit for Service to Science (MNZM)
2001 Fellow of the Royal Society of New Zealand (FRSNZ)
1999 Fellow of the New Zealand Institute of Chemistry (FNZIC)
1998 Fellow of the Royal Australian Chemical Institute (FRACI)

Awards

2016 NZ Association of Scientists Marsden Medal (Lifetime Achievement in Science), Royal Society of Chemistry Australasian Lectureship
2015 The University of Auckland Vice-Chancellor’s Commercialization Medal
2015 Senior Fellowship Award International Society of Heterocyclic Chemistry
2015 IUPAC Distinguished Women in Chemistry/Chemical Engineeering Award
2014 Westpac Trust Women of Influence Award (Science and Innovation)
2012 Rutherford Medal for exceptional contributions to science and technology sector in NZ, presented by the Royal Society of New Zealand (RSNZ)
2012 Hector Medal for outstanding works in chemical sciences, presented by the Royal Society of New Zealand (RSNZ)
2012 McDiarmid Medal for outstanding scientific research with potential human benefit presented by the Royal Society of New Zealand (RSNZ)
2011 Adrien Albert Award for sustained outstanding research in medicinal chemistry presented by the Royal Australian Chemical Institute (RACI)
2011 Dean’s Award for excellence in postgraduate supervision, The University of Auckland, NZ
2010 Natural Products Chemistry Award for outstanding contributions to the synthesis of natural products and their analogues and Simonsen Lectureship presented by the Royal Society of Chemistry (RSC), UK
2010 Editorial Board Award for refereeing the greatest number of articles for RSC journals in 2009 presented by the Royal Society of Chemistry (RSC), UK
2008 World Class New Zealander Award in Research, Science, Technology & Academia presented by Kea and New Zealand Trade and Enterprise
2008 Distinguished Research Scientist presented by the Victorian Institute for Chemical Sciences, Australia
2007 L'Oreal-UNESCO Women in Science Asia-Pacific, Laureate in Materials Science
2007 New Zealander of the Year in science category presented by North & South Magazine
2005 HortResearch Prize for excellence in the chemical sciences presented by the New Zealand Institute of Chemistry (NZIC)
2004 Novartis Chemistry Award for outstanding contributions in natural product synthesis and development of new synthetic methodology
2004 Inaugural Rosalind Franklin International Lectureship awarded to internationally recognised and successful women scientists presented by the Royal Society of Chemistry (RSC), UK
2004 James Cook Research Fellowship presented by the Royal Society of New Zealand (RSNZ)
2002 Novum Organic Chemistry Lecturer, Stockholm, Sweden
2001 Distinguished Chemist Award presented by the Federation of Asian Chemical Societies
2001 T.G.H. Jones Memorial Lecturer, University of Queensland, Australia

Professional Services

2017 Member of Kiwinet Return on Science Investment Committee (Life Sciences/Biotech)
2016 President and Titular Member IUPAC Organic and Biomolecular Chemistry Division III
2015 Panel Member European Research Council PE5 Synthetic Chemistry/Materials Science (Advanced Grants Scheme 2015-2017; Consolidator Grants 2017).
2012 Science Advisor to Freemasons Roskill Trust
2011 Member of Selection Panel, L’Oreal-UNESCO Women in Science Fellowships in Australia and NZ
2010 Member of International Jury, L’Oreal-UNESCO Women in Science Awards
2009 Chairperson of Board of Trustees, the Royal Society of New Zealand-Rutherford Foundation
2009 Elected Member, New Zealand Global Women Network
2014 to 2015
Vice-President Organic and Biomolecular Chemistry Division III of International Union of Pure and Applied Chemistry (IUPAC)
2012 to 2016
Chair of Synthesis Sub-Committee. International Union of Pure and Applied Chemistry (IUPAC)
2012 to 2015
International Advisory Board for International Society of Heterocyclic Chemistry
2012 Member of Otago University Chemistry Department Review Panel
2010 to 2012
Co-Chair of Organising Committee, Zing European Gordon Conference Synthesis/Biosynthesis of Natural Products, Egypt, 2011; Lanzarote, 2012
2010 to 2012
Chairperson of Selection Committee, Rutherford Discovery Fellowships, the Royal Society of New Zealand (RSNZ)
2010 to 2012
Member of Review Board for Elsevier Reaxys PhD Prize in Asia and Australasian
2009 to 2011
Member of Advisory Panel, the New Zealand Science Media Centre
2008 to 2010
Member of Marsden Fund Council; Convenor in Physics, Chemistry, Biochemistry Panel (2010), Convenor in Physical Sciences and Engineering Panel (2008-2009), the Royal Society of New Zealand (RSNZ)
2007 External Assessor, Australian Universities Research Quality Framework
2007 Member of Bioactives Domain Review Panel, Foundation of Research Science and Technology (FRST)
2006 to 2008
Member of Advisory Group, Leveraging New Zealand’s Natural Resources, Foundation of Research, Science and Technology (FRST)
2005 Member of International Review Panel, Karolinska Institute of Biosciences, Sweden
2005 to 2009
President,Past-President and President-Elect, International Society of Heterocyclic Chemistry (ISHC)
2003 to 2008
Member of Sub-committee in Organic Synthesis, International Union of Pure and Applied Chemistry (IUPAC)
2002 to 2008
Member of Academy Council, the Royal Society of New Zealand (RSNZ)

Editorial and Advisory Board Membership

2013 Associate Editor, Organic and Biomolecular Chemistry by the Royal Society of Chemistry (RSC)
2013 Editorial Board – Scientific Reports (2011-, Nature Publishing Group); Wiley-Blackwell Postgraduate Chemistry Series (2009-, John Wiley & Sons); The Natural Products Journal (2010-, Bentham Scientific); Journal of Heterocyclic Chemistry, (2009-, John Wiley & Sons); Organic & Biomolecular Chemistry, (2007-2012, Royal Society Chemistry); Progress in Heterocyclic Chemistry (2003-, Elsevier)
2013 International Advisory Board – Asian Journal of Organic Chemistry (2012-, John Wiley & Sons); MedChemComm (2010-, Royal Society of Chemistry); Synthesis, Synlett, Synfact (2009-, Thieme); Natural Product Reports (2005-, Royal Society of Chemistry); Marine Drugs (2008-, Molecular Diversity Preservation International); Organic Chemistry Insights (2008-, Libertas Academica); Perspectives in Medicinal Chemistry (2007-, Libertas Academica); Der Pharma Chemica (2009-, www.derpharmchemica.com); Open Glycoscience (2008-, Bentham Scientific); Biologics: Targets and Therapy (2006-, Dove Medical Press); Open Organic Chemistry Journal (2008-, Bentham Scientific); International Journal for Organic Chemistry (2002-, Arkivoc); Molecules (2002-, Springer-Verlag)
2012 to 2013
Associate Editor, Australian Journal of Chemistry, CSIRO publishing