Research Outputs

549. “A Novel Tyrosine Hyperoxidation Enables Selective Peptide Cleavage,” S. Zhang, L. M. De Leon Rodriguez, F. F. Li, R. Huang, I. K. H. Leung, P. W. R. Harris and M. A. Brimble, Chemical Science, 2022, DOI: 10.1039/D1SC06216F. (IF = 9.8)

548. “Lipidated Calcitonin Gene-related Peptide (CGRP) Peptide Antagonists Retain CGRP Receptor Activity and
Attenuate CGRP Action in vivo,” A. Jamaluddin, C.-L. Chuang, E. T. Williams, A. Siow, S. H. Yang, P. W. R. Harris, J. Petersen, R. L Bower, S. Chand, M. A. Brimble, C. S. Walker, D. L. Hay and K. M. Loomes, Frontiers in Pharmacology (Translational Pharmacology), 2022, in press. (IF = 5.8)

547. “Nitrobenzoxadiazole Derivatives of the Rat Selective Toxicant Norbormide as Fluorescent Probes for Live Cell Imaging,” Z. L. Wang, F. F. Li, R. Quach, A. Ferrarese, A. Forgiarini, M. Ferrari, C. D’Amore, S. Bova, G. Orso, F. Fusi, S. Saponara, B. Hopkins, M. A. Brimble and D. Rennison, Bioorganic and Medicinal Chemistry, 2022, in press. (IF = 3.64)

546. “A Solid Support-based Synthetic Strategy for the Site-selective Functionalization of Peptides with Organometallic Half-sandwich Moieties,” D. Truong, N. Y. S. Lam, M. Kamalov, M. Riisom, S. M. F. Jamieson, P. W. R. Harris, M. A. Brimble, N. Metzler-Nolte and C. G. Hartinger, Chemistry – A European Journal, 2022, in press. (IF = 5.2)

545. “Towards Eco-friendly Marine Antifouling Biocides – Nature Inspired Tetrasubstituted 2,5-Diketopiperazines,” T. M. Grant, D. Rennison, G. Cervin, H. Pavia, C. Hellio, V. Foulon, M. A. Brimble, P. Cahill and J. Swenson, Science of the Total Environment, 2022, 812, 154287-154298. (IF = 7.96) (included in Special Issue: “Water Health and Ecosystem.”

544. “Total Synthesis of Novel Antimicrobial β-Hairpin Capitellacin via Rapid Flow-Based SPPS Assembly
and Regioselective On-Resin Disulfide Cyclisation,” O. A. Shepperson, C. C. Hanna, M. A. Brimble, P. W. R. Harris and A. J. Cameron, International Journal of Peptide Research and Therapeutics, 2022, 28, 32-42. (IF = 1.9)

543. “Separation, Characterisation and Biological Evaluation of the Individual Isomers of the Rat Selective Toxicant Norbormide – Isolated using a Chemical Derivatization Strategy,” M. Jay-Smith, Z. L. Wang, R. Al-Kassas, E. C. Murphy, Lee Shapiro, C. T. Eason, M. A. Brimble and D.Rennison, ARKIVOC, 2021, part x, 40-53. (IF = 1.0)

542. “Investigating the Individual Importance of the Pam2Cys Ester Motifs on TLR2 Activity,” B. L. Lu, F. F. Li, I. D. Kelch, P. R. Dunbar, G. M. Williams and M. A. Brimble, European Journal of Organic Chemistry, 2021, 39, 5415-5423. (IF = 2.8)

541. “Vesiculin Derived from IGF-II Drives Increased Islet Cell Mass in a Mouse Model of Pre-diabetes,” K. L. Lee, G.M. Williams and M. A. Brimble, Islets, 2021, in press. (IF = 2.6)

540. “A Highly Efficient N-Mesityl Thiazolylidene for the Aliphatic Stetter Reaction: Stereoelectronic Quantification for Comparison of N Heterocyclic Carbene Organocatalysts,” E. S. Pearl, D. M. J. Fellner, T. Söhnel, D. P. Furkert and M. A. Brimble, Asian Journal of Organic Chemistry, 2021, 10, 2869-2875. (IF = 3.3) (VIP paper; Invited Article for 10th Anniversary Special Collection)

539. “Synthesis of the C4-C16 Polyketide Fragment of Portimines A and B,” X. Ding, H.R.M. Aitken, E.S. Pearl, D.P. Furkert and M. A. Brimble, Journal of Organic Chemistry, 2021, 86, 12840–12850. (IF = 4.4)

538. “Characterisation of Agonist Signalling Profiles and Agonist-dependent Antagonism at PACAP-responsive Receptors: Implications for Drug Discovery,” Z. Tasma, A. Siow, P.W.R. Harris, M.A. Brimble, D.L. Hay and C. J. Walker, British Journal of Pharmacology, 2022, 179, 435-453. (IF = 8.7) (Invited Article Themed Issue: Advances in Migraine and Headache Therapy (BJP 75th Anniversary)

537. “Scalable Biomimetic Syntheses of Paeciloketal B, 1-epi-Paeciloketal B and Bysspectin A,” E. K. Davison, C. E. Shepperson, Z. E. Wilson and M. A. Brimble, Journal of Natural Products, 2021, 84, 2345-2351. (IF = 4.05)

536. “The Total Chemical Synthesis and Biological Evaluation of the Cationic Antimicrobial Peptides, Laterocidine and Brevicidine,” Y. Hermant, D. Palpal-latoc, N. Kovalenko, A. J. Cameron, M. A. Brimble and P.W.R. Harris, Journal of Natural Products, 2021, 84, 2165–2174. (IF = 4.05)

535. “Antibody responses to Collagen Peptides and Streptococcal Collagen like Proteins in Acute Rheumatic Fever Patients,” D. Pilapitiya, P. W. R. Harris, P. Hanson-Manful, R. McGregor, R. Kowalczyk, J. Raynes, L. Carlton, R. Dobson, M. Baker, M. A. Brimble, S. Lukomski, and N. Moreland, Pathogens and Disease, 2021, 79(6), https://doi.org/10.1093/femspd/ftab033. (IF = 2.2)

534. “Disruption of Metallostasis in the Anaerobic Human Pathogen Fusobacterium nucleatum by the Zinc Ionophore PBT2,” E. Van Zuylen, S. Ferguson, A. Hughes, D. K. Rennison, M. A. Brimble and G. Cook, ACS Infectious Diseases, 2021, 7, 2285–2298. (IF = 4.4)

533. “A Concise Synthetic Strategy Towards the Novel Calcium-Dependent Lipopeptide Antibiotic, Malacidin A and Analogues,” N. Kovalenko, G. K. Howard, J. Swain, Y. Hermant, A. J. Cameron, G. M. Cook, S. A. Ferguson, L. A. Stubbing, P.W.R. Harris and M. A. Brimble, Frontiers in Chemistry (Chemical Biology), 2021, 9, article 687875, doi: 10.3389/fchem.2021.687875. (Invited Article for Special Issue “Secondary Metabolites and Peptides as Unique Natural Reservoirs for New Therapeutic Leads for Treatment of Cancer and Microbial Infections” hosted by M. L. Mangoni, B. Botta and F. Ghirga). (IF = 3.99)

532. “Pharmacological Characterisation of Mouse Calcitonin and Calcitonin Receptor-like Receptors Reveals Differences Compared to Human Receptors,” M. L. Garelja, R. L. Bower, M. A. Brimble, S. Chand, P.W.R. Harris, M. A. Jamaluddin, J. Petersen, A. Siow, C.S. Walker and D. L. Hay, British Journal of Pharmacology, 2022, 179, 416-434. (IF = 8.7) (Invited Article Themed Issue: Advances in Migraine and Headache Therapy (BJP 75th Anniversary)

531. “Fourth Generation Analogues of the Anticancer Peptaibol Culicinin D: Probing the Effects of Hydrophobicity and Halogenation on Cytotoxicity,” J. K. Kasim, I. Kavianinia, M. Bull, P. W. R. Harris, J. B. Smaill, A. V. Patterson and M. A. Brimble, Synthesis, 2021, 4239-4245. (IF = 3.1) (IF = 3.1) (Special Issue in honour of Prof Sarah Reisman as the recipient of the ACS Dr Margaret Faul Award Women in Chemistry Award)

530. “Engineering a Stable Complex of ERp44 with a Designed Peptide Ligand for Analyzing the Mode of Interaction of ERp44 with its Clients,” L. Hampe, P. W. R. Harris, B. Rushton, M. Radjainia, M.A. Brimble and Alok K. Mitra, Peptide Science (The American Peptide Society Journal), 2021, e24230, https://doi.org/10.1002/pep2.24230

529. “Synthesis and Characterization of Mono S-Lipidated Peptide Hydrogels: A Platform for the Preparation of Reactive Oxygen Species Responsive Materials,” “ A. Rani, L. M. De Leon-Rodriguez, I. Kavianinia, D. J. McGilvray, D. E. Williams and M. A. Brimble, Organic and Biomolecular Chemistry, 2021, 19, 3665–3677. (IF = 3.6)

528. “Amylin Analog Pramlintide Induces Migraine-like Attacks in Patients,” H. Ghanizada, M. Al-Karagholi, Mohammad, C. Walker, N. Arngrim, T. Rees, J. Petersen, A. Siow, M. Mørch-Rasmussen, S. Tan, S. O’Carroll, P. Harris, L. Skovgaard, N. Joergensen, M. A. Brimble, J. Waite, B. Rea, L. Sowers, A. Russo, D. Hay and M. Ashina, Annals of Neurology, 2021, 89, 1157-1171. (IF = 9.0)

527. “Screening a Natural Product-inspired Library for Anti-Phytophthora Activities,” S. A. Lawrence, H. F. Robinson, D. P. Furkert, M. A. Brimble and M. L. Gerth, Molecules, 2021, 26, 1819-1828. https://doi.org/10.3390/molecules26071819 (IF = 4.4)

526. “Analysis of Advanced Glycation End Products in Ribose-, Glucose- and Lactose-Crosslinked Gelatin to Correlate the Physical Changes Induced by Maillard Reaction in Films,” A. E. Etxeberria, P. A. Kilmartin, J. I. Maté; S. Prabakar, M. A. Brimble and R. Naffa, Food Hydrocolloids, 2021, 117, 106736-106750. (IF = 7.0)

525. “Thiol-ene Enabled Preparation of S-Lipidated anti-HBV Peptides,” O. A. Shepperson, A. J. Cameron, C. J. Wang, P. W. R. Harris, J. A. Taylor and M. A. Brimble, Organic and Biomolecular Chemistry, 2020, 18, in press. (IF = 3.6) https://doi.org/10.1039/D0OB01997F

524. “Total Synthesis of (±)-Leonuketal,” P. S. Grant, D. P. Furkert and M. A. Brimble, Organic Letters, 2020, 22, in press. (IF = 6.6) https://doi.org/10.1021/acs.orglett.0c03364
• (Selected for incusion in “Synthesis Workshop” https://synthesis-workshop.com/, a website that has short videio episodes on total syntheses, named reactions and other topics.)

523. “Total Synthesis of Allene-Containing Cyclic Tetrapeptide Pseudoxylallemycin C,” A. J. Cameron, C. Park, G. K. Howard, P.W. R. Harris and M. A. Brimble, Synlett, 2020, in press. (IF = 2.4) https://doi.org/10.1055/a-1282-6870

522. “C-2 Derivatized 8-Sulfonamidoquinolines as Antibacterial Compounds,” E. K. Davison, J. E. McGowan, F. F. Li, A. D. Harper, J. Y. Jeong, S. Mros, N. Harbison-Price, E. M. Van Zuylen, M. K. Knottenbelt, A. Heikal, S. A. Ferguson, M. A. McConnell, G. M. Cook, W. Krittaphol, G. F. Walker, M. A. Brimble and D. Rennison, Bioorganic and Medicinal Chemistry, 2020, in press. (IF = 3.1) https://doi.org/10.1016/j.bmc.2020.115837

521. “Rapid and Simultaneous Analysis of Advanced Glycation End Products on Silica Hydride Column: Comparison of UV, Fluorescence, and Mass Spectrometry Detectors,” R. Naffa, J. Gaar, M. Durrani, W. Zhang, C. Maidment, I. Shehadi, G.Holmes, I. Kavianinia and M. A. Brimble, Separation Science Plus, 2020, in press. https://doi.org/10.1002/sscp.202000077
• (Front Cover Image).

520. “A Ring Closing Metathesis Approach to the Formal Synthesis of (+)-Callyspongiolide,” K.-Y. Ko, Z. E. Wilson, D. P. Furkert and M. A. Brimble, ChemCatChem, 2020, (IF = 4.9) https://doi.org/10.1002/cctc.202001139
• (Invited Article for Special Collection on The Catalysis of Ring Synthesis)

519. “On-Resin Preparation of Allenamidyl Peptides: a Versatile Chemoselective Conjugation and Intramolecular Cyclisation Tool,” A. Cameron, P.W.R. Harris and M. A. Brimble, Angewandte Chemie International Edition, 2020, 59, 18054-18061. (IF = 12.1) https://doi.org/10.1002/anie.202004656
• (VIP paper – top 10% accepted manuscripts; Hot Article, Front Cover Image).

518. “Nanoribbon Self-assembly and Hydrogel Formation from an N-Octanoyl Octapeptide Derived from the Antiparallel beta-Interface of a Protein Homotetramer, “ A. Rani, I. Kavianinia, L. M. De Leon-Rodriguez, D. J. McGillivray, D. E. Williams and M. A. Brimble, Acta Biomaterialia, 2020, 114, 233-243. (IF = 7.2) https://doi.org/10.1016/j.actbio.2020.07.023

517. “Asymmetric Total Synthesis of the Naturally Occurring Antibiotic Anthracimycin,” E. K. Davison, J. L. Freeman, W. Zhang, W. M. Wuest, D. P. Furkert and M. A. Brimble, Organic Letters, 2020, 22, 5550-5554. (IF = 6.6) https://doi.org/10.1021/acs.orglett.0c01913

516. “Directed Self-Assembly of Peptide-Diketopyrrolopyrrole Conjugates – a Platform for Bio-Organic Thin Film Preparation,” A. Rani, I. Kavianinia, P. Hume, L. M. De Leon-Rodriguez, S. Kihara, D. E. Williams, D. J. McGillivray, Natalie O. V. Plank, Juliet Gerrard, Justin M. Hodgkiss and M. A. Brimble, Soft Matter, 2020, 6563-6571. (IF = 3.4) https://doi.org/10.1039/D0SM01071E
• (Invited Article for Special Issue: Peptide Soft Materials)

515. “Synthesis and Biological Evaluation of S-Lipidated Lipopeptides of a Connexin 43 Channel Inhibitory Peptide,” S.-H. Yang, C. Clemett, M. A. Brimble, S. O’Carroll and P. W. R. Harris, RSC Medicinal Chemistry, 2020, 11, 1041–1047. (pending impact factor) https://doi.org/10.1039/D0MD00172D

514. “Synthesis and Antiproliferative Activity of C- and N-Terminal Analogues of Culicinin D,” F. F. Li, L. A. Stubbing, Kavianinia, M. R. Abbattista, P. W. R. Harris, J. B. Smaill, A. V. Patterson and M. A. Brimble, Bioorganic and Medicinal Chemistry Letters, 2020, 30, 127331-127337. (IF = 2.4) https://doi.org/10.1016/j.bmcl.2020.127331

513. “Thiol-ene Enabled Chemical Synthesis of Truncated S-Lipidated Teixobactin Analogues,” V. V. Yim, A. J. Cameron, I. Kavianinia, P. W. R. Harris and M. A. Brimble, Frontiers in Chemistry (Chemical Biology), 2020, (IF = 3.8) https://doi.org/10.3389/fchem.2020.00568
• (Invited Article Special Issue: Women in Science: Chemistry)

512. “CLipP”ing on Lipids to Generate Antibacterial Lipopeptides,” V. Yim, I. Kavianinia, M. K. Knottenbelt, S. A. Ferguson, G. M. Cook, S. Swift, A. Chakraborty, J. R. Allison, A. J. Cameron, P. W. R. Harris and M. A. Brimble, Chemical Science, 2020, 11, 5759-5765. (IF = 9.1) https://doi.org/10.1039/D0SC01814G

511. “Synthesis of Paenipeptin Cʹ Analogues Employing Solution-Phase CLipPA Chemistry,” J. T. W. Tong, I. Kavianinia, S. A. Fergusson, G. M. Cook, P. W. R. Harris and M. A. Brimble, Organic and Biomolecular Chemistry, 2020, 18, 4381-4385. (IF = 3.6) https://doi.org/10.1039/D0OB00950D

510. “Design, Characterization and Evaluation of -Hairpin Peptide Hydrogels as Support for Osteoblast Cell Growth and Bovine Lactoferrin Delivery,” L. M. De Leon-Rodriguez, Y.-E. Park, D. Naot, D. S. Musson, J. Cornish and M. A. Brimble, RSC Advances, 2020, 10, 18222-18230. (IF = 3.05) https://doi.org/10.1039/D0RA03011B

509. “Guanidinylated Amphiphilic Polycarbonates with Enhanced Antimicrobial Activity by Extending the Length of the Spacer Arm and Micelle Self-Assembly,” C. A. H. Cho, C. Liang, J. Perera, M. A. Brimble, S. Swift, and J. Jin, Macromolecular Bioscience, 2020, (IF = 2.9) https://doi.org/10.1002/MABI.202000065.
• (Front Cover Image)

508. “Variable-length Ester-based Staples for α-Helical Peptides Using A Double Thiol-ene Reaction,” D. L. Paterson, J. U. Flanagan, P. R. Shepherd, P. W. R. Harris and M. A. Brimble, Chemistry: A European Journal, 2020, 26, 10826-10833. (IF = 5.2) https://doi.org/10.1002/chem.202001478

507. “Utility of the Leptospermum Scoparium Compound Lepteridine as a Chemical Marker for Manuka Honey Authenticity,” B. Lin, B. J. Daniels, M. J. Middleditch, D. P. Furkert, M. A. Brimble, J. Bonga, J. M. Stephens and K. M. Loomes, ACS Omega, 2020, 5, 8858-8866. (IF = 2.6) https://doi.org/10.1021/acsomega.0c00486

506. “Alanine Scan-guided Synthesis and Biological Evaluation of Analogues of Culicinin D, a Potent Anticancer Peptaibol,” I. Kavianinia, L. A. Stubbing, M. R. Abbattista, P. W. R. Harris, J. B. Smaill, A. V. Patterson and M. A. Brimble, Bioorganic and Medicinal Chemistry Letters, 2020, 30, 127135. (IF = 2.4) https://doi.org/10.1016/j.bmcl.2020.127135

505. “Synthesis of Isotopically Labelled αCGRP8-37 and its Lipidated Analogue,” B. L. Lu, K. M. Loomes, D. L. Hay, P. W. R. Harris and M. A. Brimble, Journal of Labelled Compounds and Radiopharmaceuticals, 2020, 1-8. (IF = 1.3) https://doi.org/10.1002/jlcr.3838

504. “Results of a Randomized, Double-Blind Phase II Clinical Trial of NY-ESO-1 Vaccine with ISCOMATRIX® Adjuvant Versus ISCOMATRIX® Alone in Participants with High Risk Resected Melanoma,” Journal for ImmunoTherapy of Cancer, J. S. Cebon, M. Gore, J. F. Thompson, I. D. Davis, G. A. McArthur, E. Walpole, M. Smithers, V. Cerundolo, P. R. Dunbar, D. MacGregor, C. Fisher, M. Millward, P. Nathan, M. P. N. Findlay, Peter Hersey, T. R. J. Evans, C. H. Ottensmeier, J. Marsden, A. G. Dalgleish, P. G. Corrie, M. Marples, M. A. Brimble, G. M. Williams, S. Winkler, L. Endo-Munoz1, C. S. A. Tutuka, R. Venhaus, L. J. Old, D. Haack, E. Maraskovsky, A. Behren and W. Chen, Journal for ImmunoTherapy of Cancer, 2020, 8, e000410. (IF = 8.7) https://doi.org/10.1136/jitc-2019-000410

503. “Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2,” N. Harbison-Price, S. Ferguson, A. Heikal, G. Taiaroa, K. Hards, Y. Nakatani, D. Rennison, M. A. Brimble, I. El Deeb, L. Bohlmann, C. McDevitt, M. von Itzstein, M. Walker and G. Cook, mSphere (American Society for Microbiology), 2020, 5:e00157-20; (IF = 4.4) https:// doi.org/10.1128/mSphere.00157-20

502. “Synthesis of Peptide Homo- and Heterodimers as Potential Mimics of PDGF-BB,” L. A. Stubbing, H. Kaur, S. X. Feng, M. Aalderink, M. Dragunow and M. A. Brimble, Peptide Science (The American Peptide Society Journal), 2020, 112, e24150. (IF = 2.0) https:// doi.org/10.1002/pep2.24150
• (Invited Article Special Issue honoring the lifetime achievements of Louis Carpino)

501. “Direct Synthesis of Cyclic Lipopeptides using Intramolecular Native Chemical Ligation and Thiol-ene CLipPA Chemistry,” V. V. Yim, I. Kavianinia, A. J. Cameron, P. W. R. Harris and M. A. Brimble, Organic and Biomolecular Chemistry, 2020, 18, 2838-2844. (IF = 3.6) https://doi.org/10.1039/D0OB00203H
• (Front Cover image and HOT article https://pubs.rsc.org/en/journals/articlecollectionlanding?sercode=ob&themeid=8400b4e4-d6c4-4fb9-a31f-b236dae3e39f)

500. “Intermolecular Diels-Alder Cycloaddition/Cross-coupling Sequences of 2-Bromo-1,3-Butadienes,” H. Choi, H. Shirley, H. Aitken, T. Schulte, T. Söhnel, P. Hume, M. A. Brimble and D. P. Furkert, Organic Letters, 2020, 22, 1022-1027. (IF = 6.6) https://doi.org/10.1021/acs.orglett.9b04567
• (Used for video for undergraduate organic chemistry students @chemhelpASAP; bit.ly/Brimble_vid)

499. “Replacement of the Acrid tert-Butylthiol and an Improved Isolation Protocol for Cysteine Lipidation on a Peptide or Amino Acid (CLipPA),” S.-H. Yang, Y. O. J. Hermant, P. W. R. Harris and M. A. Brimble, European Journal of Organic Chemistry, 2020, 36, 944-947. (IF = 3.1) https://doi.org/10.1002/ejoc.201901696

498. “Substituted Sulfonamide Bioisosteres of 8-Hydroxyquinoline as Zinc-dependent Antibacterial Compounds,” Bioorganic and Medicinal Chemistry, D. Rennison, J. E McGowan, A. D. Harper, E. K. Davison, J. Y. Jeong, S. Mros, N. Harbison-Price, E. M. Van Zuylen, M. K. Knottenbelt, A. Heikal, S. A. Ferguson, M. A. McConnell, G. M. Cook, W. Krittaphol, G. F. Walker and M. A. Brimble, Bioorganic and Medicinal Chemistry, 2020, 28, 127110. (IF = 3.1) https://doi.org/10.1016/j.bmcl.2020.127110

497. “A Catalytic Asymmetric Ene Reaction For Direct Preparation of -Hydroxy-1,4-Diketones As Intermediates In Natural Product Synthesis,” H. R. M. Aitken, D. P. Furkert and M. A. Brimble, Synlett, 2020, 31, 687-690. (IF = 2.4) https://doi.org/10.1055/s-0037-1610748

496. “Advanced Glycated Apo A-IV Loses its Ability to Prevent the LPS-induced Reduction in Cholesterol Efflux-related Gene Expression in Macrophages,” L. Okuda, R. T. Iborra, P. R. Pinto, U. F. Machado, M. L. C. Correa-Giannella, R. Pickford, T. Woods, M. A. Brimble, K.-A. Rye and M. Passarelli, Mediators of Inflammation, 2020, vol 2020, p. 1-11. (IF = 3.5) https://doi.org/10.1155/2020/6515401

495. “Distinct Patterns of Internalization of Different Calcitonin Gene-related Peptide Receptors,” J. Gingell, T. Rees, E. Hendrikse, A. Siow, D. Rennison, J. Scotter, P. Harris, M. A. Brimble, C. Walker and D. Hay, ACS Pharmacology and Translational Science, 2020, 3, 296-304. https://doi.org/10.1021/acsptsci.9b00089

494. “Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors,” M. Garelja, M. Au, M. A. Brimble, J. Gingell, E. Hendrikse, A. Lovell, N. Prodan, P. M. Sexton, A. Siow, C. Walker, H. Watkins, G. Williams, D. Wootten, S. Yang, P. Harris and D. Hay, ACS Pharmacology and Translational Science, 2020, 3, 246-262. https://doi.org/10.1021/acsptsci.9b00083

493. “Synthesis and SAR Analysis of Lipovelutibols B and D and their Lipid Analogues,” A. J. Cameron, E. K. Davison, C. An, L. A. Stubbing, P. R. Dunbar, P. W. R. Harris and M. A. Brimble, Journal of Organic Chemistry, 2020, 85, 1401-1406. (IF = 4.8) https://doi.org/10.1021/acs.joc.9b02348
• (Invited Article Special Issue “Modern Peptide and Protein Chemistry”)

492. “Divalent Cannabinoid-1 Receptor Ligands: A Linker Attachment Point Survey of SR141716A for Development of High-Affinity CB1R Molecular Probes,” P. S. Grant, N. Kahlcke, K. Govindpani, M. Hunter, C. MacDonald, M. A. Brimble, M. Glass and D. P. Furkert, Bioorganic and Medicinal Chemistry Letters, 2019, 29, 126644-126651. (IF = 2.42) https://doi.org/10.1016/j.bmcl.2019.126644

491. “A Versatile Boc Solid Phase Synthesis of Daptomycin and Analogues using Site Specific, On-resin Ozonolysis to Install the Kynurenine Residue,” B. Xu, Y. Hermant, S.-H. Yang, P. W. R. Harris and M. A. Brimble, Chemistry: A European Journal, 2019, 25, 14101-14107. (IF = 5.2) https://doi.org/10.1002/chem.201903725
• (Inside Front Cover image)

490. “Synthesis and Evaluation of Novel TLR2 Agonists as Potential Adjuvants for Cancer Vaccines,” B. Lu, G. M. Williams, D. Verdon, P. R. Dunbar and M. A. Brimble, Journal of Medicinal Chemistry, 2020, 63, 2282-2291. (IF = 6.3) https://doi.org/10.1021/acs.jmedchem.9b01044
• (Invited Article for the Special Issue “Women in Medicinal Chemistry”)

489. “Synthesis of the Tetracyclic Cores of the Integrastatins, Epicoccolide A and Epicocconigrone A,” J. Jeong, J. Sperry and M. A. Brimble, Journal of Organic Chemistry, 2019, 84, 11935-11944. (IF = 4.8) https://doi.org/10.1021/acs.joc.9b01796

488. “Microtiter Screening Reveals Oxygen-Dependent Antimicrobial Activity of Natural Products Against Mastitis-Causing Bacteria,” S. A. Ferguson, A. Menorca, E. M. Van Zuylen, C.-Y. Cheung, M. McConnell, D. Rennison, M. A. Brimble, K. Bodle, S. McDougall, G. M. Cook and A. Heikal, Frontiers in Microbiology: Antimicrobials, Resistance and Chemotherapy, 2019, 10, 1995. https://doi.org/10.3389/fmicb.2019.01995

487. “Pharmacological Characterization and Investigation of N-Terminal Loop Amino Acids of Adrenomedullin 2 that are Important for Receptor Activation,” H. Musa, E. R. Hendrikse, M. A. Brimble, M. L. Garelja, H. A. Watkins, P. W. R. Harris, D. L. Hay, Biochemistry, 2019, 58, 3468-3474. (IF = 3.0) https://doi.org/10.1021/acs.biochem.9b00571

486. “A Chiral Auxiliary-Based Synthesis of the C5-C17 trans-Decalin Framework of Anthracimycin,” J. Freeman, D. P. Furkert and M. A. Brimble, Organic Chemistry Frontiers, 2019, 6, 2954-2963. (IF = 5.5) https://doi.org/10.1039/C9QO00769E

485. “Highly Diastereoselective Synthesis of syn-1,3-Dihydroxyketone Motifs from Propargylic Alcohols via Unusual Spiroepoxide Intermediates,” X.Ding, D. P. Furkert and M. A. Brimble, Angewandte Chemie International Edition, 2019, 58, 11830-11835. (IF = 12.1) https://doi.org/10.1002/anie.201905736

484. “Synthesis and Antiproliferative Activity of Culicinin D Analogues Containing Simplified AHMOD-based Residues,” L. A. Stubbing, I. Kavianinia, M. R. Abbattista, P. W. R. Harris, J. B. Smaill, A. V. Patterson and M. A. Brimble, European Journal of Medicinal Chemistry, 2019, 177, 235-246. (IF = 5.1) https://doi.org/10.1016/j.ejmech.2019.05.052

483. “The Selective Rat Toxicant Norbormide Blocks KATP Channels in Smooth Muscle Cells but not in Insulin-Secreting Cells,” F. Fusi, S. Bova, S. Saponara, A. Trezza, O. Spiga, B. Hopkins, D. Rennison and M. A Brimble, Frontiers in Pharmacology (Cardiovascular and Smooth Muscle Pharmacology section), 2019, 10, 598. (IF = 4.4) https://doi.org/10.3389/fphar.2019.00598

482. “Glucoregulatory Activity of Vesiculin in Insulin Sensitive and Resistant Mice,” K. L. Lee, J. F. Aitken, G. M. Williams, M. A. Brimble and G. J. S. Cooper, Peptides, 2019, 116, 1-7. (IF = 2.85) https://doi.org/10.1016/j.peptides.2019.04.011

481. “Site-specific Glycations of Aβ1–42 Affect Fibril Formation and are Neurotoxic,” J. Ng, H. Kaur, T. Collier, K. Chang, A. E. S. Brooks, J. R. Allison, M. A. Brimble, A. Hickey and N. P. Birch, J. Biol. Chem., 2019, 294, 8806-8818. (IF = 4.0) https://doi.org/10.1074/jbc.ra118.006846

480. “A Potent Fluorescent CGRP Analogue Enables Visualisation of Receptor Internalisation,” L. R. Yule, M. L. Garelja, E. H. Hendrikse, J. G. Gingell, D. R. Poyner, P. W. R. Harris, M. A. Brimble, D. L. Hay, Peptide Science, 2019, 111:e24126. (IF = 2.0) https://doi.org/10.1002/pep2.24126

479. “Live Applications of Norbormide-based Fluorescent Probes in Drosophila melanogaster,” A. Forgiarini, Z. Wang, C, D’Amore, M. Jay-Smith, F. F. Li, B. Hopkins, M. A. Brimble, A, Pagetta, S. Bersani, S. De Martin, B. Napoli, S. Bova, D. Rennison, G. Orso, PLOS ONE, 2019, 14: e0211169. (IF = 2.8) https://doi.org/10.1371/journal.pone.0211169

478. “Investigations of the Key Macrolactamisation Step in the Synthesis of Cyclic Antimicrobial Tetrapeptide Pseudoxylallemycin A,” A. J. Cameron, C. J. Squire, A. Gérenton, L. A. Stubbing, P. W. R. Harris and M. A. Brimble, Organic and Biomolecular Chemistry, 2019, 17, 3902-3913. (IF = 3.6) https://doi.org/10.1039/C9OB00227H
• (Highlighted by H. Yamamoto and A. Banerjee, Synfacts, 2019, 15, 825)

477. “Synthesis of Endolides A and B; Naturally Occurring N-Methylated Cyclic Tetrapeptides,” E. K. Davison, A. J. Cameron, P. W. R. Harris and M. A. Brimble, MedChemComm, 2019, 10, 693-698. (IF = 3.6) https://doi.org/10.1039/C9MD00050J
• (Invited Article for Special Issue on Natural Products, Selected for Front Cover image)

476. “Convenient Access to 5-Membered Cyclic Iminium Ions: Evidence for a Stepwise [4+2] Cycloaddition Mechanism,” J. L. Freeman, D. P. Furkert and M. A. Brimble, Organic and Biomolecular Chemistry, 2019, 17, 2705-2714. (IF = 3.6) https://doi.org/10.1039/C9OB00262F

475. “Enhancing T Cell Responses and Tumour Immunity by Vaccination with Peptides Conjugated to a Weak NKT Cell Agonist,” B. J. Compton, K. J. Farrand, C.-W. Tang, T. L. Osmond, M. Speir, A. Authier-Hall, J. Wang, P. M. Ferguson, S. T. S. Chan, R. J. Anderson, T. R. Cooney, C. M. Hayman, G. M. Williams, M. A. Brimble, C. R. Brooks, L.-K. Yong, L. S. Metelitsah, D. M. Zajonc, D. I. Godfrey, O. Gasser, R. Weinkove, G. F. Painter and I. F. Hermans, Organic and Biomolecular Chemistry, 2019, 17, 1225-1237. (IF = 3.6) https://doi.org/10.1039/C8OB02982B

474. “Structure-Activity Relationships of Wollamide Cyclic Hexapeptides with Activity against Drug-resistant and Intracellular Mycobacterium tuberculosis,” Z. Khalil, T. Hill, L. De Leon Rodriguez, R.-J. Lohman, H. Hoang, N. Reiling, D. Hillemann, M. A. Brimble, D. Fairlie, A. Blumenthal and R. Capon, Antimicrobial Agents and Chemotherapy, 2019, 63, e01773-18. (IF = 4.5) https://doi.org/10.1128/AAC.01773-18

473. “Efficient Synthesis and Characterisation of the Amyloid Beta Peptide, Aβ1-42, using a Double Linker System,” J. K. Kasim, I. Kavianinia, J. Ng, P. W. R. Harris, N. P. Birch and M. A. Brimble, Organic and Biomolecular Chemistry, 2019, 17, 30-34. (IF = 3.6) https://doi.org/10.1039/C8OB02929F

472. “A Synthetic Approach to ‘Click’ Neoglycoprotein Analogues of EPO Employing One-pot Native Chemical Ligation and CuAAC Chemistry,” D. J. Lee, A. J. Cameron, T. H. Wright, P. W. R. Harris and M. A. Brimble, Chemical Science, 2019, 10, 815-828. (IF = 9.1) https://doi.org/10.1039/C8SC03409E
• Highlighted in Chemistry World: https://www.chemistryworld.com/news/erythropoietin-benefits-from-controlled-sugar-coating/3009861.article

471. “A Chemometric Analysis of Compounds from Native New Zealand Medicinal Flora,” L. I. Pilkington, X. Yang, M.-W. Liu, Y. Hemar, M.A. Brimble and Jóhannes Reynisson, Chemistry- An Asian Journal, 2019, 14, 1117-1127. (IF = 3.7) https://doi.org/10.1002/asia.201800803

470. “Synthesis of the Bicyclic Lactone Core of Leonuketal Enabled by a Telescoped Diels-Alder Reaction Sequence,” P. S. Grant, M. A. Brimble and D. P. Furkert, Chemistry – An Asian Journal, 2019, 14, 1128-1135. (IF = 3.7) https://doi.org/10.1002/asia.201800903
• (Invited Article – Special Issue dedicated to Chemistry in New Zealand)

469. “Synthesis and Biological Characterization of a New Norbormide Derived Bodipy Fl-Conjugated Fluorescent Probe for Cell Imaging” C. D’Amore, G. Orso, A. Forgiarini, G. Ceolotto, D. Rennison, G. Ribaudo, M. Jay Smith, B. Hopkins, M. A. Brimble and S. Bova, Frontiers in Pharmacology (Experimental Pharmacology and Drug Discovery), 2018, 9 (1055), 1-13. (IF = 4.4) https://doi.org/10.3389/fphar.2018.01055

468. “Reactivity of 2-Nitropyrrole Systems: Strategic Evolution of Synthetic Approaches to Nitropyrrole Natural Products,” X.-B. Ding, M. A. Brimble and D. P. Furkert, Journal of Organic Chemistry, 2018, 83, 12460-12470. (IF = 4.8) https://doi.org/10.1021/acs.joc.8b01692

467. “Genome Mining, Isolation, Chemical Synthesis and Biological Evaluation of a Novel Lanthipeptide, Tikitericin and N-Truncated Analogues, from the Extremophilic Microorganism Thermogemmatispora Strain T81,” B. Xu, E. J. Aitken, B. P. Baker, C. Turner, J. E. Harvey, M. B. Stott, J. F. Power, P. W.R. Harris, R. A. Keyzers and M. A. Brimble, Chemical Science, 2018, 9, 7311-7317. (IF = 9.1) https://doi.org/10.1039/C8SC02170H
• (Selected as Article for Chemical Science “Pick of the Week” and for Back Cover)

466. “Cardiac Troponins may be Irreversibly Modified by Glycation: Novel Potential Mechanisms of Cardiac Performance Modulation,” J. Janssens, B. Ma, M. A. Brimble, J. Van Eyk, L. Delbridge and K. Mellor, Scientific Reports – Nature, 2018, 8, 16084-16098. (IF = 4.1) https://doi.org/10.1038/s41598-018-33886-x

465. “Solid-Phase Thiol-ene Lipidation of Peptides for the Synthesis of a Potent CGRP Receptor Antagonist,” E. T. Williams, P. W. R. Harris, M. A. Jamaluddin, K. M. Loomes, D. L. Hay and M. A. Brimble, Angewandte Chemie International Edition, 2018, 57, 11640-11643. (IF = 12.1) https://doi.org/10.1002/anie.201805208

464. “Photoaffinity Cross-linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-related Peptide Binding to the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein 1 (CLR/RAMP1) Complex,” J. Simms, R. Uddin, T. Sakmar, J. Gingell, M. Garelja, D. Hay, M. A. Brimble, P. Harris, C. Reynolds, D. Poyner, ACS Biochemistry, 2018, 57, 4915-4922. (IF = 2.9) https://doi.org/10.1021/acs.biochem.8b00502

463. “Total Synthesis of the Proposed Structure of Talarolide A,” S. Zhang, L. M. De Leon Rodriguez, R. Huang, I. K.H. Leung, P. W. R. Harris and M. A. Brimble, Organic and Biomolecular Chemistry, 2018, 16, 5286-5293. (IF = 3.6) https://doi.org/10.1039/C8OB01230J

462. “Supramolecular Threading of Peptide Hydrogel Fibrils,” N. Hauptstein, L. M. De Leon Rodriguez, A. K. Mitra, Y. Hemar, I. Kavianinia, N. Li, V. Castelletto, I. Hamley, M. A. Brimble, ACS Biomaterials Science and Engineering, 2018, 4, 2733-2738. (IF = 3.2) https://doi.org/10.1021/acsbiomaterials.8b00283

461. “Supplementation of Blackcurrant Anthocyanins increased Cyclic Glycine-Proline in the Cerebrospinal Fluid of Parkinson Patients, a Potential Treatment to improve Insulin-like Growth Factor-1 Function,” D. Fen, Y. Alamri, K. Liu, M. MacAskill, P. Harris, M. Brimble, J. Dalrymple-Alford, T. Anderson, T. Prickett, O.Menzies, A. Laurenson and J. Guan, Nutrients, 2018, 10, 714-725. (IF = 4.2) https://doi.org/10.3390/nu10060714

460. “Tethering Fragment-Based Drug Discovery to Identify Inhibitors of the Essential Respiratory Membrane Protein Type II NADH Dehydrogenase,” A. Heikal, Y. Nakatani, W. Jia, C. Wilson, D. Rennison, M. R. Weimar, E. J. Parker and M. A. Brimble, G. M. Cook, Bioorganic and Medicinal Chemistry Letters, 2018, 28, 2239-2243. (IF = 2.4) https://doi.org/10.1016/j.bmcl.2018.05.048

459. “Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin,” R. Bower, L. Yule, T. Rees, G. Deganutti, E. Hendrikse, P. Harris, R. Kowalczyk, Z. Ridgway, A. Wong, K. Swierkula, D. Raleigh, A. Pioszak, M. A. Brimble, C. Reynolds, C. Walker and D. Hay, ACS Pharmacology and Translational Science, 2018, 1, 32-49. (new journal impact factor not available) https://doi.org/10.1021/acsptsci.8b00002

458. “The Role for Cyclic Glycine-Proline, a Biological Regulator of Insulin-like Growth Factor-1 in Pregnancy-related Obesity and Weight Changes,” J. Guan, G. Singh-Mallah, K. Liu, E. Thorstensen, P. Shorten, E. A. Mitchell, R. Taylor, P. Harris, M. A. Brimble, J. M. D. Thompson and R. Murphy, Journal of Biological Regulators and Homeostatic Agents, 2018, 32, 11-25. (IF = 1.5) (no DOI, https://www.researchgate.net/publication/325905407_The_role_for_cyclic_Glycine-Proline_a_biological_regulator_of_insulin-like_growth_factor-1_in_pregnancy-related_obesity_and_weight_changes only link found with fill (proof) text available)

457. “Desacetyl--melanocyte Stimulating Hormone and -Melanocyte Stimulating Hormone are required to Regulate Energy Balance,” K. G. Mountjoy, A. Caron, K. Hubbard, A. Shome, A. C. Grey, B. Sun, S. Bould, M. Middleditch, B. Pontré, A. McGregor, P. W. R. Harris, R. Kowalczyk and M. A. Brimble, R. Botha1, K. M. L. Tan, S. J. Piper, C. Buchanan, S. Lee, A. P. Coll and J. K. Elmquis, Molecular Metabolism, 2018, 9, 207-216. (IF = 6.8) https://doi.org/10.1016/j.molmet.2017.11.008

456. “Total Synthesis of (-)-Peniphenone A,” M. Pantin, M. A. Brimble and D. P. Furkert, Journal of Organic Chemistry, 2018, 83, 7049-7059. (IF = 4.8) https://doi.org/10.1021/acs.joc.7b03231
• (Selected for Special Issue “Synthesis of Antibiotics and Related Molecules”)

455. “Using Chemical Synthesis to Probe Structure-Activity Relationships of the Glycoactive Bacteriocin Glycocin F,” S. Bisset, S.-H. Yang, Z. Amso, P. Harris, M. Patchett, M. A. Brimble and G. Norris, ACS Chemical Biology, 2018, 13, 1270-1278. (IF = 5.0) https://doi.org/10.1021/acschembio.8b00055

454. “A Double-click Approach to the Protecting Group Free Synthesis of Glycoconjugates,” S. R. Alexander, G. M. Williams, M. A. Brimble and A. J. Fairbanks, Organic and Biomolecular Chemistry, 2018, 16, 1258-1262. (IF = 3.6) https://doi.org/10.1039/C8OB00072G

453. “Receptor Activity-Modifying Proteins have Limited Effects on the Class B G Protein-Coupled Receptor Calcitonin Receptor-like Receptor Stalk,” M. Garelja, C. Walker, A. Siow, S. Yang, P. Harris, M. A. Brimble, H. Watkins, J. Gingell and D. Hay, Biochemistry, 2018, 8, 1410-1422. (IF = 2.9) https://doi.org/10.1021/acs.biochem.7b01180

452. “Total Synthesis and Conformational Study of The Anti-tubercular Cyclic Peptide Callyaerin A Bearing a Rare Rigidifying (Z)-2,3-Diaminoacrylamide Moiety,” M. A. Brimble, S. Zhang, L. M. De Leon Rodriguez, I. K. H. Leung, G. M. Cook and P. W. R. Harris Angewandte Chemie International Edition, 2018, 57, 3631-3635.
(IF = 12.1) https://doi.org/10.1002/ange.201712792
• (Selected for “Cover Image” and as “VIP paper”, < 10% of accepted papers receive this accolade; highlighted on ChemistryViews.org
see: http://www.chemistryviews.org/details/ezine/10879614/Total_Synthesis_of_Callyaerin_A.html)

451. “Total Synthesis of the Highly N-Methylated Acetylene-Containing Anticancer Peptide Jahanyne,” A. Siow, G. Opiyo, I. Kavianinia, F. F. Li, D. P. Furkert, P. W. R Harris and M. A. Brimble, Organic Letters, 2018, 20, 788-791. (IF = 6.6) https://pubs.acs.org/doi/10.1021/acs.orglett.7b03925

450. “Total Chemical Synthesis of Glycocin F and Analogues: S-Glycosylation Confers Improved Antimicrobial Activity,” Z. Amso, S. W. Bisset, S.-H. Yang, P. W. R. Harris, T. H. Wright, C. D. Navo, M. L. Patchett, G. E. Norris and M. A. Brimble, Chemical Science, 2018, 9, 1686-1691. (IF = 9.1) https://doi.org/10.1039/C7SC04383J

449. “Molecular Weight and Charge Density Effects of Guanidinylated Biodegradable Polycarbonates on Antimicrobial Activity and Selectivity,” C. A. H. Cho, C. Liang, J. Perera, J. Liu, K. G. Varnava, V. Sarojini, R. P. Cooney, D. J. McGillivray, M. A. Brimble, S. Swift and J. Jin, Biomacromolecules, 2018, 19, 1389-1401. (IF = 5.2) https://doi.org/10.1021/acs.biomac.7b01245

448. “AGE-Albumin Enhances ABCA1 Degradation by Ubiquitin-proteasome and Lysosomal Pathways in Macrophages” R. T. Iborra, A. Machado-Lima, L. S. Okuda, P. R. Pinto, E. R. Nakandakare, U. F. Machado, M. L. Correa-Giannella, R. Pickford, T. Woods, M. A. Brimble, K.-A. Rye, R. Lu, S. Yokoyama and M. Passarelli, Journal of Diabetes and its Complications, 2018, 32, 1-10. https://doi.org/10.1016/j.jdiacomp.2017.09.012

447. “A Phase I Vaccination Study with Dendritic Cells Loaded with NY-ESO-1 and alpha-Galactosylceramide: Induction of Polyfunctional T cells in High-risk Melanoma Patients,” O. Gasser, K. J. Sharples, C. Barrow, G. M. Williams, E. Bauer, C. E. Wood, B. Mester, M. Dzhelali, G. Caygill, J. Jones, C. M. Hayman, V. A. Hinder, J. Macapagal, M. McCusker, R. Weinkove, G. F. Painter, M. A. Brimble, M. P. Findlay, P. R. Dunbar and Ian F. Hermans, Cancer Immunology, Immunotherapy, 2018, 67, 285-298. (IF = 4.8) https://doi.org/10.1007/s00262-017-2085-9

446. “Anthranilate Phosphoribosyltransferase: Binding Determinants for 5′-Phospho-alpha-D-ribosyl-1′-pyrophosphate (PRPP) and the Implications for Inhibitor Design” G. L. Evans, D. P. Furkert, N. Abermil, P. Kundu, K. M. de Lange, E. J. Parker, M. A. Brimble, E. N. Baker and J. S. Lott, Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics, 2018, 1866, 264-274. (IF = 3.0) https://doi.org/10.1016/j.bbapap.2017.08.018

445. “Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid-Peptide Vaccine,” R. J. Anderson, J. Li, L. Kedzierski, B. J. Compton, C. M. Hayman, T. L. Osmond, C.-W. Tang, K. J. Farrand, H.-F. Koay, C. F. D. S. S. E. Almeida, L. R. Holz, G. M. Williams, M. A. Brimble, Z. Wang, M. Koutsakos, K. Kedzierska, D. I. Godfrey, I. F. Hermans, S. J. Turner and G. F. Painter, ACS Chemical Biology, 2017, 12, 2898-2905. (IF = 5.0) https://doi.org/10.1021/acschembio.7b00845

444. “N-Acetylcysteine Counteracts Adipose Tissue Macrophage Infiltration and Insulin Resistance Elicited by Advanced Glycated Albumin in Healthy Rats,” K. S. Da Silva, P. R. Pinto, N. T. Fabre, D. J. Gomes, K. Thieme, L. S. Okuda, R. T. Iborra, V. G. Freitas, M. H. M. Shimizu, W. R. Teodoro, S. K. N. Marie, T. Woods, M. A Brimble, R. Pickford, K.-A. Rye, M. Okamoto, S. Catanozi, M. L. Correa-Giannela, U. F. Machado and M. Passarelli, Frontiers in Physiology, 2017, 8, 723. (IF = 4.0) https://dx.doi.org/10.3389%2Ffphys.2017.00723

443. “Stereochemical Characterisation of Polyketide Stereotriads Synthesized via Hydrogen Mediated Asymmetric Syn-Crotylation,” M. Pantin, J. G. Hubert, T. Söhnel, M. A. Brimble and D. P. Furkert, Journal of Organic Chemistry, 2017, 82, 11225-11229 (IF = 4.8) https://doi.org/10.1021/acs.joc.7b01820

442. “Synthesis and Biological Evaluation of Novel Teixobactin Analogues,” C. E. Schumacher, P. W.R. Harris, X.-B. Ding, B. Krause, T. H. Wright, G. M. Cook, D. P. Furkert and M. A. Brimble, Organic and Biomolecular Chemistry, 2017, 15, 8755-8760. (IF = 3.6) https://doi.org/10.1039/C7OB02169K

441. “General Synthesis of the Nitropyrrolin Family of Natural Products via Regioselective CO2-Mediated Alkyne Hydration,” X.-B. Ding, D. P. Furkert and M. A. Brimble, Organic Letters, 2017, 19, 5418-5421. (IF = 6.6) https://doi.org/10.1021/acs.orglett.7b02687
• (included in Organic Highlights: https://www.organic-chemistry.org/Highlights/2018/28May.shtm)

440. “Understanding the Metal Mediated Assembly and Hydrogel Formation of a β-Hairpin Peptide,” L. M. De Leon Rodriguez, Y. Hemar, A. K. Mitra and M. A. Brimble, Biomaterials Science, 2017, 5, 1993-1997. (IF = 4.2) https://doi.org/10.1039/C7BM00512A

439. “Synthesis and Incorporation of an Advanced Lipid Peroxidation End-product Building Block into Collagen Mimetic Peptides,” I. Kavianinia, S.‐H. Yang, H. Kaur, P.W. R. Harris, R. C. J. Dobson, A. J. Fairbanks and M. A. Brimble, Chemical Communications, 2017, 53, 8459-8462. (IF = 6.5) https://doi.org/10.1039/c7cc05025a

438. “Incorporation of ‘Click’ Chemistry Glycomimetics Dramatically Alters Triple-helix Stability in an Adiponectin Model Peptide,” K. R. Lutteroth, P. W. R. Harris, T. H. Wright, H. Kaur, K. Sparrow, S.-H. Yang, G. J. S. Cooper and M. A. Brimble, Organic and Biomolecular Chemistry, 2017, 15, 5602-5608. (IF = 3.6) https://doi.org/10.1039/C7OB01388D

437. “Bioinspired Total Synthesis and Stereochemical Revision of the Fungal Metabolite Pestalospirane B,” S. Badrinarayanan, C. J. Squire, J. Sperry and M. A. Brimble, Organic Letters, 2017, 19, 3414-3417. (IF = 6.6) https://doi.org/10.1021/acs.orglett.7b01371
• (selected for inclusion in ACS Select Collection focused on natural products total synthesis because of its high scientific quality and broad appeal).

436. “Total Synthesis and Stereochemical Revision of the 2-Formylpyrrole Alkaloid Hemerocallisamine I,” J. M. Wood, D. P. Furkert and M. A. Brimble, Journal of Natural Products, 2017, 80, 1926-1929. (IF = 3.8) https://doi.org/10.1021/acs.jnatprod.7b00314

435. “Norborn-2-en-7-ones as Physiologically-Triggered Carbon Monoxide-Releasing Prodrugs” J. T. B. Kueh, N. J. Stanley, R. J. Hewitt, L. M. Woods, L. Larsen, J. C. Harrison, D. Rennison, M. A. Brimble, I. A. Sammut, and D. S. Larsen, Chemical Science, 2017, 8, 5454-5459. (IF = 9.1) https://doi.org/10.1039/C7SC01647F

434. “Stability of Polyelectrolyte-Coated Iron Nanoparticles for T2-Weighted Magnetic Resonance Imaging” A. J. McGrath, C. Dolan, S. Cheong, D. A. J. Herman, B. Naysmith, F. Zong, P. Galvosas, K. J. Farrand, I. F. Hermans, M. A. Brimble, D. E. Williams, J. Jin, R. Tilley and R. D. Herman, Journal of Magnetism and Magnetic Materials, 2017, 439, 251-258. (IF = 2.4) https://doi.org/10.1016/j.jmmm.2017.04.026

433. “Structure-Activity Relationship Study of the Tumour-Targeting Peptide A20FMDV2 via Modification of Lys16, Leu13, and N- and/or C-Terminal Functionality” K.-Y. Hung, P. W. R. Harris, A. Desai, J. F. Marshall and M. A. Brimble, European Journal of Medicinal Chemistry, 2017, 136, 154-164. (IF = 3.5) https://doi.org/10.1016/j.ejmech.2017.05.008

432. “Unexpected Direct Synthesis of N-Vinyl Amides Through Vinyl Azide-Enolate [3+2] Cycloaddition” H. Choi, H. J. Shirley, P. A. Hume, D. P. Furkert and M. A. Brimble, Angewandte Chemie International Edition, 2017, 56, 7420-7424. (IF = 12.0) https://doi.org/10.1002/anie.201702727
• (Selected by Editorial Board of Synfacts for its important insights; see: Synfacts 2017, 13(08), 0864; https://doi.org/10.1055/s-0036-1590632; Contributors: P.Knochel, J. M. Hammann

431. “Remarkable Influence of Cobalt Catalysis on Epoxide Ring-Opening with Sulfoxonium Ylides” M. L. Jamieson, N. Z. Brant, M. A. Brimble and D. P. Furkert, Synthesis, 2017, 49, 3952-3956. (IF = 2.7 ) : ) https://doi.org/10.1055/s-0036-1588814
• (Invited Feature Article and Special Topic “Cobalt in Organic Synthesis” Cover Page, Synthesis, 2017, 49, 3885; DOI: 10.1055/s-0036-1589510)

430. “Protecting Group Free Synthesis of Glycosyl Thiols from Reducing Sugars in Water; Application to the Production of N-glycan Glycoconjugates” S. R. Alexander, D. Lim, Z. Amso, M. A. Brimble and A. J. Fairbanks, Organic and Biomolecular Chemistry, 2017, 15, 2152-2156. (IF = 3.6) https://doi.org/10.1039/C7OB00112F

429. “MALDI-Imaging Enables Direct Observation of Kinetic and Thermodynamic Products of Mixed Peptide Fiber Assembly” K. Medini, B. West, D. E. Williams, M. A. Brimble and J. A. Gerrard, Chemical Communications, 2017, 53, 1715-1718. (IF = 6.4) https://doi.org/10.1039/C6CC10146A

428. “Cyclization of Linear Tetrapeptides Containing N-Methylated Amino Acids by Using 1-Propanephosphonic Acid Anhydride” S. Zhang, L. M. De Leon Rodriguez, E. Lacey, A. M. Piggott, I. K. H. Leung and M. A. Brimble, European Journal of Organic Chemistry, 2017, 33, 149-158. (IF = 3.1) https://doi.org/10.1002/ejoc.201601016

427. “An Efficient Chemical Synthesis of Lassomycin Enabled by an On-resin Lactamisation-Off-resin Methanolysis Strategy and Preparation of Chemical Variants” P. W. R. Harris, G. M. Cook, I. K. H. Leung and M. A. Brimble, Australian Journal of Chemistry, 2017, 70, 172-183. (IF = 1.226) http://dx.doi.org/10.1071/CH16499
• (Invited Article for Special Edition on “Peptide Chemistry” and selected for inclusion in Special Virtual Issue devoted to the best of local medicinal chemistry in the past 5 years see: https://www.publish.csiro.au/ch/virtualissue/2942)

426. “Characterizing the Mode of Action of Extracellular Connexin43 Channel Blocking Mimetic Peptides in an in vitro Ischemia Injury Model” Y. Kim, J. M. Griffin, P. W. R. Harris, S. H. C. Chan, L. F. B. Nicholson, M. A. Brimble, S. J O’Carroll and C. R. Green, Biochimica and Biophysica Acta (General), 2017, 1861, 68-78. (IF = 5.08) https://doi.org/10.1016/j.bbagen.2016.11.001

425. “Multifunctional Thermoresponsive Designer Peptide Hydrogels” L. M. De Leon Rodriguez, Y. Hemar, G. Mo, A. K. Mitra, J. Cornish and M. A. Brimble, Acta Biomaterialia, 2017, 47, 40-49. (IF = 6.1) https://doi.org/10.1016/j.actbio.2016.10.014
• (Highlighted in Gyros Protein Technologies Newsletter, https://cdn2.hubspot.net/hubfs/378579/1-PTI/emailers/Review%20Article/Multifunctional%20thermoresponsive%20peptide%20hydrogels%20designed%20to%20meet%20the%20demands%20of%20biomedical%20applications.pdf?hsCtaTracking=8e443296-781b-4086-b13f-1db4bcf1d20b%7C8653de01-2be4-4790-aa07-a17b1f3f9ba; 3000 subscribers)

424. “Solid-Phase Synthesis of the Peptaibol Alamethicin U-22324 Using a Double-Linker Strategy” A. Siow, K.-Y. Hung, P. W. R. Harris and M. A. Brimble, European Journal of Organic Chemistry, 2017, 350-354. (IF = 3.1) https://doi.org/10.1002/ejoc.201601102

423. “2-Nitropyrrole Cross-Coupling Enables a Second Generation Synthesis of the Heronapyrrole Antibiotic Natural Product Family” X. Ding, D. P. Furkert and M. A. Brimble, Chemical Communications, 2016, 52, 12638-12641. (IF = 6.4) https://doi.org/10.1039/C6CC07532K

422. “A NBD Derivative of the Selective Rat Toxicant Norbormide as a New Probe for Living Cell Imaging”
C. D’Amore, G. Orso, F. Fusi, M. A. Pagano, G. Miotto, A. Forgiarini, S. De Martin, G. Castellani, G. Ribaudo, D. Rennison, M. A. Brimble, B. Hopkins, A. Ferrarese and S. Bova, Frontiers in Pharmacology (Experimental Pharmacology and Drug Discovery), 2016, 7(315), 1-13. (IF = 4.4) Open Access Article. http://dx.doi.org/10.3389/fphar.2016.00315

421. “Cyclic Enecarbamates as Precursors of alpha,beta-Unsaturated Iminium Ions: Reactivity and Synthesis of 6,6-Spirocyclic Ring Systems” Z. Wang, N. Krogsgaard-Larsen, B. Daniels, D. P. Furkert and M. A. Brimble, Journal of Organic Chemistry, 2016, 81, 10366-10375 (IF = 4.8) https://doi.org/10.1021/acs.joc.6b01343

420. “Glycated Albumin Induces Lipid Infiltration in Mice Aorta Independently of DM and RAS Local Modulation by Inducing Lipid Peroxidation and Inflammation” D. J. Gomes, A. P. Velosa, L. S. Okuda, F. B. Fusco, K. S. da Silva, P. R. Pinto, E. R. Nakandakare, M. L. Correa-Giannella, T. Woods, M. A. Brimble, R. Pickford, K.-A. Rye, W. R. Teodoro, S. Catanozi and M. Passarelli, Journal of Diabetes and Its Complications, 2016, 30, 1614-1621. (IF = 2.0) https://doi.org/10.1016/j.jdiacomp.2016.07.001

419. “Structure Activity Relationship Study on the Peptide Hormone Preptin, a Novel Bone-anabolic Agent for the Treatment of Osteoporosis” Z. Amso, R. Kowalczyk, M. Watson, Y.-E. Park, K. E. Callon, D. S. Musson, J. Cornish and M. A. Brimble, Organic and Biomolecular Chemistry, 2016, 14, 9163-9440 (IF = 3.6) https://doi.org/10.1039/C6OB01455K
• (Selected for “Front Cover”)

418. “Total Synthesis and Stereochemical Revision of the Anti-Tuberculosis Peptaibol Trichoderin A” I. Kavianinia, L. Kunalingam, P. W. R. Harris, G. M. Cook and M. A. Brimble, Organic Letters, 2016, 18, 3878-3881. (IF = 6.6) https://doi.org/10.1021/acs.orglett.6b01886

417. “Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol” R. Quach, D. P. Furkert and M. A. Brimble, Journal of Organic Chemistry, 2016, 81, 8343-8350. (IF = 4.8) https://doi.org/10.1021/acs.joc.6b01503

416. “Synthesis of Psychrophilin E” S. T. Y. Ngen, H. Kaur, P. A. Hume, D. P. Furkert and M. A. Brimble, Journal of Organic Chemistry, 2016, 81, 7635-7643. (IF = 4.8) https://doi.org/10.1021/acs.joc.6b01369

415. “Synthesis of the 2-Formylpyrrole Spiroketal Pollenopyrroside A and Structural Elucidation of Xylapyrroside A, Shensongine A and Capparisine B” J. M. Wood, D. P. Furkert and M. A. Brimble, Organic and Biomolecular Chemistry, 2016, 14, 7569-7664. (IF = 3.6) https://doi.org/10.1039/C6OB01361A

414. “Maternally Administered Cyclic-Glycine-Proline Increases Insulin-like Growth Factor-1 Bioavailability and Novelty Recognition in Developing Offspring” G. Singh-Mallah, K. Singh, C. D. McMahon, P. Harris, M. A. Brimble, E. Thorstensen and J. Guan, Endocrinology, 2016, 157, 3130-3139. (IF = 4.4) https://doi.org/10.1210/en.2016-1189

413. “Synthesis and Biological Evaluation of Analogues of the Potent ADAM8 Inhibitor Cyclo(RLsKDK) for the Treatment of Inflammatory Diseases and Cancer Metastasis” V. Yim, A. F. M. Noisier, K.-Y. Hung, J. W. Bartsch, U. Schlomann and M. A. Brimble, Bioorganic and Medicinal Chemistry, 2016, 24, 4032-4037. (IF = 2.8) https://doi.org/10.1016/j.bmc.2016.06.042

412. “Stereoselective Synthesis of the Rat Selective Toxicant Norbormide” M. Jay-Smith, E. C. Murphy, L. Shapiro, C. T. Eason, M. A. Brimble and D. Rennison, Tetrahedron, 2016, 72, 5331-5342. (IF = 2.6) https://doi.org/10.1016/j.tet.2016.07.014

411. “Synthesis of Natural Cyclopentapeptides Isolated from Dianthus chinensis” S. Zhang, Z. Amso, L. M. De Leon Rodriguez, H. Kaur and M. A. Brimble, Journal of Natural Products, 2016, 79, 1769−1774. (IF = 3.8) https://doi.org/10.1021/acs.jnatprod.6b00152

410. “Identification of Anticancer Agents Based on the Thieno[2,3-b]pyridine and 1H-Pyrazole Molecular Scaffolds” C. Eurtivong, I. Reynisdóttir, S. Kuczma, D. P. Furkert, M. A. Brimble and J. Reynisson, Bioorganic and Medicinal Chemistry, 2016, 24, 3521-3526. (IF = 2.8) https://doi.org/10.1016/j.bmc.2016.05.061

409. “Synthesis and in vitro Bone Cell Activity of Analogues of the Cyclohexapeptide Dianthin G” Z. Amso, R. Kowalczyk, Y.-E. Park, M. Watson, J.-M. Lin, D. S. Musson, J. Cornish and M. A. Brimble, Organic and Biomolecular Chemistry, 2016, 14, 6231-6243. (IF = 3.6) https://doi.org/10.1039/c6ob00983b
• (Invited article for “Selective Chemistry with Peptides and Proteins” themed issue edited by Professor Phil Dawson)

408. “Isolation, Structural Elucidation and Synthesis of Lepteridine from Mānuka (Lepstospermum scoparium) Honey” B. J. Daniels, G. Prijic, S. Meidinger, K. M. Loomes, J. M. Stephens, R. C. Schlothauer, D. P. Furkert and M. A. Brimble, Journal of Agricultural and Food Chemistry, 2016, 64, 5079–5084. (IF = 2.9) https://doi.org/10.1021/acs.jafc.6b01596

407. “Controlling Gelation with Sequence: Towards Programmable Peptide Hydrogels” K. Medini, B. W. Mansel, M. A. K. Williams, M. A. Brimble, D. E. Williams, J. A. Gerrard, Acta Biomaterialia, 2016, 43, 30-37. (IF = 6.1) https://doi.org/10.1016/j.actbio.2016.07.021

406. “Substituted Carbazoles – A New Class of Anthelmintic Agent” D. Rennison, S. M. Gueret, O. Laita, R. J. Bland, I. A. Sutherland, I. K. Boddy and M. A. Brimble, Australian Journal of Chemistry, 2016, 69, 1268-1276. (IF = 1.6) https://doi.org/10.1071/CH16169

405. “Synthesis and Amylin Receptor Activity of Glycomimetics of Pramlintide using Click Chemistry” L. R. Yule, R. L. Bower, H. Kaur, R. Kowalczyk, D. L. Hay and M. A. Brimble, Organic and Biomolecular Chemistry, 2016, 14, 5238-5245 (IF = 3.6) https://doi.org/10.1039/C6OB00850J
• (Invited article for “Selective Chemistry with Peptides and Proteins” themed issue edited by Professor Phil Dawson; Selected for “Front Cover”)

404. “Radiation Damage and Racemic Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily” H. Yeung, C. J. Squire, Y. Yosaatmadja, S. Panjikar, G. López, A. Molina, E. N. Baker, P. W. R. Harris and M. A. Brimble, Angewandte Chemie International Edition, 2016, 55, 7930-7933. (IF = 11.3) https://doi.org/10.1002/anie.201602719
• (Selected for “Front Cover” and as “VIP paper”, < 5% of accepted papers receive this accolade; Featured in Chemistry in Australia, “Elusive Potato Protein Structure Solved,” September issue 2016, p 11)

403. “Receptor Activity-Modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties” H. A. Watkins, M. Chakravarthy, R. S. Abhayawardana, J. J. Gingell, M. Garelja, M. Pardamwar, J. M. W. R. McElhinney, A. Lathbridge, A. Constantine, P. W. R. Harris, T.-Y. Yuen, M. A. Brimble, J. Barwell, D. R. Poyner, M. J. Woolley, A. C. Conner, A. A. Pioszak, C. A. Reynolds and D. L. Hay, Journal of Biological Chemistry, 2016, 291, 11657-11675. (IF = 4.6) https://doi.org/10.1074/jbc.m115.688218

402. “Synthesis and Structural Insight into ESX-1 Substrate Protein C, an Immunodominant Mycobacterium Tuberculosis-Secreted Antigen” S. J. Son, P. W. R. Harris, C. J. Squire, E. N. Baker and M. A. Brimble, Biopolymers (Peptide Science), 2016, 106, 267-274. (IF = 2.9) https://doi.org/10.1002/bip.22838

401. “Lipidation of Cysteine or Cysteine-Containing Peptides Using the Thiol-ene Reaction (CLipPA)” S.-H. Yang, P. W. R. Harris, G. M. Williams and M. A. Brimble, European Journal of Organic Chemistry, 2016, 33, 2608-2616. (IF = 3.1) https://doi.org/10.1002/ejoc.201501375
• (Selected for “Front Cover” and as a “Hot Topics” Article for all Wiley journals: http://www.wiley-vch.de/util/hottopics/clickchem/)

400. “A New High-Capacity Metal Ion-Complexing Gel Containing Cyclen Ligands” C. Dolan, F. Douret, D. C. Ware, P. J. Brothers, J. Jin, M. A. Brimble and D. Williams, RSC Advances, 2016, 6, 23645-23652. (IF = 3.8) https://doi.org/10.1039/C6RA00604C

399. “A Peptide Hydrogel Derived from a Fragment of Human Cardiac Troponin C” L. M. De Leon-Rodriguez, M. Kamalov, Y. Hemar, A. K. Mitra, V. Castelletto, D. Hermida-Merino, I. W. Hamley and M. A. Brimble, Chemical Communications, 2016, 52, 4056-4059. (IF = 6.4) https://doi.org/10.1039/C6CC00209A

398. “Fluorescent IGF-II Analogues for FRET-based Investigations into the Binding of IGF-II to the IGF-1R” J. M. Cottam Jones, P. W. R. Harris, D. B. Scanlon, B. E. Forbes, M. A. Brimble and A. D. Abell, Organic and Biomolecular Chemistry, 2016, 14, 2698-2705. (IF = 3.6) https://doi.org/10.1039/C5OB02110C

397. “Divergent Reactivity via Cobalt Catalysis: An Epoxide Olefination” M. Jamieson, P. Hume, D. P. Furkert and M. A. Brimble, Organic Letters, 2016, 18, 468-471. (IF = 6.6) https://doi.org/10.1021/acs.orglett.5b03514

396. “A Convergent Synthesis of Gonytolide C Using an Intramolecular Oxa-Michael Addition” F. F. Li, D. J. Atkinson, D. P. Furkert and M. A. Brimble, European Journal of Organic Chemistry, 2016, 33, 1145-1155. (IF = 3.3) https://doi.org/10.1002/ejoc.201501402

395. “The Nedd4-1 WW Domain Recognizes the PY Motif Peptide through a Coupled Folding and Binding Equilibrium” V. Panwalkar, P. Neudecker, M. Schmitz, J. Lecher, M. Schulte, K. Medini, M. Stoldt, M. A. Brimble, D. Willbold and A. Dingley, Biochemistry, 2016, 55, 659-674. (IF = 3.0) https://doi.org/10.1021/acs.biochem.5b01028

394. “Enantioselective Synthesis of BE Ring Analogues of Methyllycaconitine” E. Dickson, L. I. Pilkington, M. A. Brimble and D. Barker, Tetrahedron, 2016, 72, 400-414. (IF = 2.6) https://doi.org/10.1016/j.tet.2015.11.057

393. “Synthesis and Activity of a Diselenide Bond Mimetic of the Antimicrobial Protein Caenopore-5” K. Medini, P. W. R. Harris, A. Menorca, K. Hards, G. M. Cook and M. A. Brimble, Chemical Science, 2016, 7, 2005-2010. (IF = 9.2) https://doi.org/10.1039/C5SC04187B

392. “Electrochemically-Controlled Grafting of Hydrophilic Brushes from Conducting Polymer Substrates” L. T. Strover, J. Malmström, L. Stubbing, M. A. Brimble and J. Travas-Sejdic, Electrochimica Acta, 2016, 188, 57-70. (IF = 4.5) https://doi.org/10.1016/j.electacta.2015.11.106

391. “Total Synthesis and Structural Confirmation of the Antimalarial Naphthopyrone Lasionectrin” V. L. Poral, D. P. Furkert and M. A. Brimble, Organic Letters, 2015, 17, 6214-6217. (IF = 6.7) https://doi.org/10.1021/acs.orglett.5b03202

390. “Glicentin-Related Pancreatic Polypeptide Inhibits Glucose-Stimulated Insulin Secretion from the Isolated Pancreas of Adult Male Rats” L. Whiting, K. W. Stewart, D. L. Hay, P. W. R. Harris, Y. S. Choong, A. R. J. Phillips, M. A. Brimble and G. J. S. Cooper, Physiological Reports, 2015, 3, e12638, 1-12. (IF = 2.13) https://doi.org/10.14814/phy2.12638

389. “Peptide Binding to a Bacterial Signal Peptidase Visualized by Peptide Tethering and Carrier-driven Crystallization” Y. T. Ting, P. W. R. Harris, G. Batot, M. A. Brimble, E. N. Baker and P. G. Young, International Union of Crystallography Journal (IUCrJ), 2016, 3, 10-19. (IF = 3.1) https://dx.doi.org/10.1107%2FS2052252515019971

388. “Synthesis of the Spiroketal Core of the Pinnatifinoside Family of Natural Products” D. F. Chorley, D. P. Furkert and M. A. Brimble, European Journal of Organic Chemistry, 2015, 32, 314-319. (IF = 3.3) https://doi.org/10.1002/ejoc.201501225

387. “Fatty Acid Derived Pro-toxicants of the Rat Selective Toxicant Norbormide” H. Choi, D. Conole, D. J. Atkinson, O. Laita, M. Jay-Smith, M. A. Pagano, G. Ribaudo, M. Cavalli, S. Bova, B. Hopkins, M. A. Brimble and D. Rennison, Chemistry and Biodiversity, 2016, 13, 762-775. (IF = 1.56) https://doi.org/10.1002/cbdv.201500241

386. “Improved Synthesis of the Unnatural Amino Acids AHMOD and AMD, Components of the Anticancer Peptaibol Culicinin D” K.-Y. Ko, S. Wagner, S.-H. Yang, D. P. Furkert and M. A. Brimble, Journal of Organic Chemistry, 2015, 80, 8631-8636. (IF = 4.6) https://doi.org/10.1021/acs.joc.5b01265

385. “Improved Strategy for the Synthesis of the Anticancer Agent Culicinin D” M. Stach, A. J. Weidkamp, S.-H. Yang, K.-Y Hung, D. P. Furkert, P. W. R. Harris, J. B. Smaill, A. V. Patterson and M. A. Brimble, European Journal of Organic Chemistry, 2015, 6341-6350. (IF = 3.3) https://doi.org/10.1002/ejoc.201500872

384. “NKT Cell-Dependent Glycolipid-Peptide Vaccines with Potent Anti-tumour Activity” R. J. Anderson, B. J. Compton, C.-W Tang, A. Authier-Hall, C. M. Hayman, G. W. Swinerd, R. Kowalczyk, P. W. R. Harris, M. A Brimble, D. S. Larsen, O. Gasser, R. Weinkove, I. F. Hermans and G. F. Painter, Chemical Science, 2015, 6, 5120-5127. (IF = 9.2) https://doi.org/10.1039/C4SC03599B
• (Selected as an Edge Article and Front Cover)

383. “Synthesis of DOHNAA, a Mycobacterium tuberculosis Cholesterol CD Ring Catabolite and FadD3 Substrate” L. A. Stubbing, J. S. Lott, S. S. Dawes, D. P. Furkert and M. A. Brimble, European Journal of Organic Chemistry, 2015, 6075-6083. (IF = 3.3) https://doi.org/10.1002/ejoc.201500698

382. “Regulation and Quality Control of Adiponectin Assembly by Endoplasmic Reticulum Chaperone ERp44” L. Hampe, M. Radjainia, C. Xu, P. W. R. Harris, G. Bashiri, D. C. Goldstone, M. A. Brimble, Y. Wang and A. K. Mitra, Journal of Biological Chemistry, 2015, 290, 18111-18123. (IF = 4.6) https://doi.org/10.1074/jbc.m115.663088

381. “Convergent Chemo-Enzymatic Synthesis of Mannosylated Glycopeptides; Targeting of Putative Vaccine Candidates to Antigen Presenting Cells” J. D. MacIntosh, M. A. Brimble, A. E. S. Brooks, P. R. Dunbar, R. Kowalczyk, Y. Tomabechi and A. J. Fairbanks, Chemical Science, 2015, 6, 4636-4642. (IF = 9.2) https://doi.org/10.1039/c5sc00952a

380. “Cell-Targeted Platinum Nanoparticles and Nanoparticle Clusters” S. Papst, M. A. Brimble, C. W. Evans, D. J. Verdon, V. Feist, P. R. Dunbar, R. D. Tilley and D. E. Williams, Organic and Biomolecular Chemistry, 2015, 13, 6567-6572. (IF = 3.6) https://doi.org/10.1039/C5OB00822K

379. “On Resin Synthesis and Cross-linking of Collagen Peptides Containing the Advanced Glycation End-product Pyrraline via Maillard Condensation” M. Kamalov, P. W. R. Harris, J. M. Wood and M. A. Brimble, Chemical Communications, 2015, 51, 9475-9478. (IF = 6.4) https://doi.org/10.1039/C5CC03052H

378. “Structural Basis for Receptor Activity-modifying Protein-Dependent Selective Peptide Recognition by a G protein-Coupled Receptor” J. M. Booe, C. S. Walker, J. Barwell, G. Kuteyi, J. Simms, M. A. Jamaluddin, M. L. Warner, R. M. Bill, P. W. R. Harris, M. A. Brimble, D. R. Poyner, D. L. Hay and A. A. Pioszak, Molecular Cell, 2015, 58, 1040-1052. (IF = 15.3) https://doi.org/10.1016/j.molcel.2015.04.018

377. “Diabetes-Induced Alterations in Tissue Collagen and Carboxymethyllysine in Rat Kidneys: Association with Increased Collagen-degrading Proteinases and Amelioration by Cu(II)-selective Chelation” S. Brings, S. Zhang, Y. S Choong, S. Hogl, M. Middleditch, M. Kamalov, M. A. Brimble, D. Gong and G. J. S. Cooper, Biochimica and Biophysica Acta (BBA) – Molecular Basis of Disease, 2015, 1852, 1610-1618. (IF = 5.1) https://doi.org/10.1016/j.bbadis.2015.04.014

376. “Replacement of the CysA7-CysB7 Disulfide Bond with a 1,2,3-Triazole Linker Causes Unfolding in Insulin Glargine” G. M. Williams, K. Lee, X. Li, G. J. S. Cooper and M. A. Brimble, Organic and Biomolecular Chemistry, 2015, 13, 4059-4063. (IF = 3.6) https://doi.org/10.1039/C5OB00160A

375. “Studies Towards Development of Asymetric Double-Mannich Reactions of Chiral 2-Oxocyclohexanecarboxylate Derivatives with Bis(aminol)ethers” K. J. Sparrow, S. Carley, T. Söhnel, D. Barker and M. A. Brimble, Tetrahedron, 2015, 71, 2210-2221. (IF = 2.8) https://doi.org/10.1016/j.tet.2015.02.083

374. “Chemical Synthesis of a Polypeptide Backbone Derived from the Primary Sequence of the Cancer Protein NY-ESO-1 Enabled by Kinetically Controlled Ligation and Pseudoprolines” P. W. R. Harris and M. A. Brimble, Biopolymers (Peptide Science), 2015, 104, 116-127. (IF = 2.9) https://doi.org/10.1002/bip.22621

373. “Synthesis of the Spirocyclic Framework of Sesterterpenoid Natural Products” J. G. Hubert, D. P. Furkert and M. A. Brimble, Journal of Organic Chemistry, 2015, 80, 2715-2723. (IF = 4.8) https://doi.org/10.1021/jo502897u
• Highlighted by Douglas Taber in Organic Chemistry Highlights “Metal-Mediated C-C Ring Construction”: www.organic-chemistry.org/Highlights/2015/14December.shtm

372. “Preparation of cis-gamma-Hydroxycarvone Derivatives for Synthesis of Sesterterpenoid Natural Products: Total Synthesis of Phorbin A” J. G. Hubert, D. P. Furkert and M. A. Brimble, Journal of Organic Chemistry, 2015, 80, 2231-2239. (IF = 4.6) https://doi.org/10.1021/jo502748s

371. “Physicochemical Studies on the Copper(II) Binding by Glycated Collagen Telopeptides” M. Kamalov, P. W. R. Harris, C. G. Hartinger, G. M. Miskelly, G. J. S. Cooper and M. A. Brimble, Organic and Biomolecular Chemistry, 2015, 13, 3058-3063. (IF = 3.6) https://doi.org/10.1039/C4OB02536A

370. “Total Synthesis of the Cyclic Depsipeptide YM-280193, a Platelet Aggregation Inhibitor” H. Kaur, P. W. R. Harris, P. J. Little and M. A. Brimble, Organic Letters, 2015, 17, 492-495. (IF = 6.3) https://doi.org/10.1021/ol503507g

369. “Synthesis of Novel Triazole-Containing Phosphonate Polymers” C. Dolan, B. Naysmith, S. F. R. Hinkley, I. M. Sims, M. A. Brimble, D. E. Williams and J. Jin, Australian Journal of Chemistry, 2015, 68, 680-686. (IF = 1.6) https://doi.org/10.1071/CH14513

368. “Using Mass Spectrometry to Detect, Differentiate and Semiquantitate Closely Related Peptide Hormones in Complex Milieu: Measurement of IGF-II and Vesiculin” K. L. Lee, M. J. Middleditch, G. M. Williams, M. A. Brimble and G. J. S. Cooper, Endocrinology, 2015, 156, 1194-1199. (IF = 4.5) https://doi.org/10.1210/en.2014-1593

367. “Synthesis of the Antimicrobial S-Linked Glycopeptide, Glycocin F” M. A. Brimble, P. J. Edwards, P. W. R. Harris, G. E. Norris, M. L. Patchett, T. H. Wright, S.-H. Yang, and S. E. Carley, Chemistry – A European Journal, 2015, 21, 3556-3561. (IF = 5.7) https://doi.org/10.1002/chem.201405692

366. “Chemical Synthesis of gamma-Secretase Activating Protein using Pseudo-glutamines as Ligation Sites” P. W. R. Harris, C. Squire, P. G. Young and M. A. Brimble, Biopolymers (Peptide Science), 2015, 104, 37-45. (IF = 2.9) https://doi.org/10.1002/bip.22600

365. “Neuroprotection with Glycine-2-Methylproline-Glutamate (G-2MePE) after Hypoxic-ischemic Brain Injury in Adult Rats,” S. Mathai, P. W. R. Harris, M. A. Brimble, A. J. Gunn and J. Guan, Journal of Experimental Stroke and Translational Medicine, 2015, 6, 1-11. An open access journal. https://www.openaccessjournals.com/articles/neuroprotection-with-glycine2methylprolineglutamate-g2mepe-after-hypoxicischemic-brain-injury-in-adult-rats-11896.html

364. “Virtual Screening for Novel Atg5-Atg16 Complex Inhibitors for Autophagy Modulation” E. Robinson, E. Leung, A. M. Matuszek, N. Krogsgaard-Larsen, D. P. Furkert, M. A. Brimble, A. Richardson and J. Reynisson, MedChemComm, 2015, 6, 239-246. (IF = 2.7) https://doi.org/10.1039/C4MD00420E

363. “Synthesis of the Carbon Skeleton of the Griseorhodins” D. J. Atkinson, D. P. Furkert and M. A. Brimble, Tetrahedron, 2015, 71, 91-101. (IF = 2.8) https://doi.org/10.1016/j.tet.2014.11.030

362. “Chemical Synthesis of a Pore-Forming Antimicrobial Protein, Caenopore-5, by Using Native Chemical Ligation at a Glu-Cys Site” K. Medini, P. W. R. Harris, K. Hards, A. J. Dingley, G. M. Cook and M. A. Brimble, ChemBioChem, 2015, 16, 328-336. (IF = 3.7) https://doi.org/10.1002/cbic.201402513

361. “Formal Synthesis of Nanaomycin D via a Hauser-Kraus Annulation Using a Chiral Enone-Lactone”
N. P. S. Hassan, B. J. Naysmith, J. Sperry and M. A. Brimble, Tetrahedron, 2015, 71, 7137-7143. (IF = 2.8) https://doi.org/10.1016/j.tet.2014.09.014
• (Invited Article for Tetrahedron Special Edition in memory of Professor Alan Katritzky)

360. “Nonsymmetrical Azocarbonamide Carboxylates as Effective Mitsunobu Reagents” D. P. Furkert, B. Breitenbach, L. Juen, I. Sroka, M. Pantin and M. A. Brimble, European Journal of Organic Chemistry, 2014, 31, 7806-7809. (IF = 3.3) https://doi.org/10.1002/ejoc.201403152

359. “Total Synthesis of the Macrocyclic N-Methyl Enamides Palmyrolide A and 2S-Sanctolide A” A. D. Wadsworth, D. P. Furkert and M. A. Brimble, Journal of Organic Chemistry, 2014, 79, 11179-11193. (IF = 4.6) https://doi.org/10.1021/jo502238r

358. “Synthesis and Evaluation of 9-Deoxy Analogues of (–)-Thysanone, an Inhibitor of HRV 3C Protease” J. Y. Jeong, J. Sperry, J. A. Taylor and M. A. Brimble, European Journal of Medicinal Chemistry, 2014, 87, 220-227. (IF = 4.1) https://doi.org/10.1016/j.ejmech.2014.09.063

357. “Protecting-Group-Free One-pot Synthesis of Glycoconjugates Directly from Reducing Sugars” D. Lim, M. A. Brimble, R. Kowalczyk, A. J. A. Watson and A. J. Fairbanks, Angewandte Chemie International Edition, 2014, 53, 11907-11911. (IF = 13.7) https://doi.org/10.1002/anie.201406694

356. “Synthesis of the Revised Structure of Acortatarin A” H. M. Geng, L. A. Stubbing, J.L.-Y. Chen, D. P. Furkert and M. A. Brimble, European Journal of Organic Chemistry, 2014, 31, 6227-6241. (IF = 3.3) https://doi.org/10.1002/ejoc.201403000

355. “Convergent Chemoenzymatic Synthesis of a Library of Glycosylated Analogues of Pramlintide: Structure-Activity Relationships of Amylin Receptor Agonism” R. Kowalczyk, M. A. Brimble, Y. Tomabechi, A. J. Fairbanks, M. Fletcher and D. L. Hay, Organic and Biomolecular Chemistry, 2014, 12, 8142-8151. (IF = 3.6) https://doi.org/10.1039/C4OB01208A
• (Selected for “Front Cover”)

354. “Toward an Asymmetric Synthesis of the Dimeric Pyranonaphthoquinone Antibiotic Crisamicin A” M. A. Brimble, N. P. S. Hassan, B. J. Naysmith and J. Sperry Journal of Organic Chemistry, 2014, 79, 7169-7178. (IF = 4.6) https://doi.org/10.1021/jo501344c

353. “An Efficient Fmoc Solid-Phase Synthesis of an Amphiphile of the Neuroprotective Agent Glycyl-prolyl-glutamic acid” P. W. R. Harris, G. T. Molenaar, Z. Amso, G. P. Savage and M. A. Brimble, Synlett, 2014, 25, 2221-2224. (IF = 2.7) https://doi.org/10.1055/s-0034-1378539

352. “Total Synthesis of Virgatolide B via Exploitation of Intramolecular Hydrogen Bonding” P. A. Hume, D. P. Furkert and M. A. Brimble, Journal of Organic Chemistry, 2014, 79, 5269-5281. (IF = 4.6) https://doi.org/10.1021/jo5008527

351. “Synthesis of Truncated Analogues of Preptin-(1-16), and Investigation of Their Ability to Stimulate Osteoblast Proliferation” R. Kowalczyk, S. H. Yang, M. A. Brimble, K. E. Callon, M. Watson, Y.-E. Park and J. Cornish, Bioorganic and Medicinal Chemistry, 2014, 22, 3565-3572. (IF = 3.2) https://doi.org/10.1016/j.bmc.2014.05.026

350. “Structure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus Polymerisation” P. G. Young, T. Proft, P. W. R. Harris, M. A. Brimble and E. N. Baker, PLOS ONE, 2014, 9, e99135/1-e99135/13, 13 pp. (IF = 3.7) https://doi.org/10.1371/journal.pone.0099135

349. “Expedient Synthesis of Peptides Containing Nε-Carboxymethyllysine” M. Kamalov, S. Yang, P. W. R. Harris, G. J. S. Cooper and M. A. Brimble, Synlett, 2014, 25, 1835-1838. (IF = 2.7) https://doi.org/10.1055/s-0033-1378305

348. “An Investigation of the Role of the Adiponectin Variable Domain on the Stability of the Collagen-like Domain” P. W. R. Harris, L. Hampe, M. Radjainia, M. A. Brimble and A. K. Mitra, Biopolymers (Peptide Science), 2014, 102, 313-321. (IF = 2.9) https://doi.org/10.1002/bip.22501

347. “Synthesis and Biological Evaluation of the Osteoblast Proliferating Cyclic Peptides Dianthins G and H” H. Kaur, A. M. Heapy, R. Kowalzcyk, Z. Amso, M. Watson, J. Cornish and M. A. Brimble, Tetrahedron, 2014, 70, 7788-7794. (IF = 2.8) https://doi.org/10.1016/j.tet.2014.04.035
• (Invited Article for Special Issue on Peptide Macrocycles)

346. “Site-Specific Cross-linking of Collagen Peptides by Lysyl Advanced Glycation Endproducts” M. Kamalov, P. W. R. Harris, G. J. S. Cooper and M. A. Brimble, Chemical Communications, 2014, 50, 4944-4946. (IF = 6.4) https://doi.org/10.1039/C4CC02003K

345. “One-Pot Synthesis of Functionalized Noble Metal Nanoparticles Using a Rationally Designed Phosphopeptide” S. Papst, M. A. Brimble, R. D. Tilley, D. E. Williams, Particle and Particle Systems Characterization, 2014, 31, 971-975. https://doi.org/10.1002/ppsc.201300381

344. “Synthesis and Methemoglobinemia-inducing Properties of Benzocaine Isosteres Designed as Humane Rodenticides” D. Conole, T. M. Beck, M. Jay-Smith, M. D. Tingle, C. T. Eason, M. A. Brimble and D. Rennison, Bioorganic and Medicinal Chemistry, 2014, 24, 2220-2235. (IF = 3.1) https://doi.org/10.1016/j.bmc.2014.02.013

343. “Plant Antimicrobial Peptides Snakin-1 and Snakin-2: Chemical Synthesis and Insights into the Disulfide Connectivity” P. W. R. Harris, S.-H Yang, A. Molina, G. López, M. Middleditch and M. A. Brimble, Chemistry – A European Journal, 2014, 20, 5102-5110. (IF = 5.8) https://doi.org/10.1002/chem.201303207

342. “Preparation of Truncated Orf Virus Entry Fusion Complex Proteins by Chemical Synthesis” H. Yeung, P. W. R. Harris, C. J. Squire, E. N. Baker and M. A. Brimble, Journal of Peptide Science, 2014, 20, 398-405. (IF = 2.1) https://doi.org/10.1002/psc.2627

341. “Synthesis of Highly Substituted Pyranonaphthalene Spiroketals Related to the Griseusins using a Hauser-Kraus Annulation Strategy” B. J. Naysmith, D. P. Furkert and M. A. Brimble, Tetrahedron, 2014, 70, 1199-1206. (IF = 2.8) https://doi.org/10.1016/j.tet.2013.12.066

340. “A Convenient Method for the Asymmetric Synthesis of Fluorinated alpha-Amino Acids from Alcohols” F. Drouet, A. F. M. Noisier, C. S. Harris, D. P. Furkert and M. A. Brimble, European Journal of Organic Chemistry, 2014, 1195-1201. (IF = 3.3) https://doi.org/10.1002/ejoc.201301718
• (Selected for “Front Cover”)

339. “Synthesis of the 2-Methylene Analogue of the HRV 3C Protease Inhibitor Thysanone (2-Carbathysanone)” K. Schünemann, D. P. Furkert, E. C. Choi, S. Connelly, J. D. Fraser, J. Sperry and M. A. Brimble, Organic and Biomolecular Chemistry, 2014, 12, 905-912. (IF = 3.6) https://doi.org/10.1039/c3ob41951g

338. “Total Synthesis of Heronapyrrole C” X.-B. Ding, D. P. Furkert, R. J. Capon and M. A. Brimble, Organic Letters, 2014, 16, 378-381. (IF = 6.4) https://doi.org/10.1021/ol403246j

337. “Synthesis of the Spiroacetal Core of the Cephalosporolide Family of Natural Products, O. C. Finch, D. P. Furkert and M. A. Brimble, Tetrahedron, 2014, 70, 590-596. (IF = 2.8) https://doi.org/10.1016/j.tet.2013.12.012

336. “A Maillard Approach to 2-Formylpyrroles: Synthesis of Magnolamide, Lobechine and Funebral”
T.-Z. Yuen, S. E. Eaton, T. M. Woods, D. P. Furkert, K. W. Choi and M. A. Brimble, European Journal of Organic Chemistry, 2014, 1431-1437. (IF = 3.3) https://doi.org/10.1002/ejoc.201301639

335. “Iridium-Catalysed C-H Borylation Facilitates a Total Synthesis of the HRV 3C Protease Inhibitor (±)-Thysanone” K. Schünemann, D. P. Furkert, S. Connelly, J. D. Fraser, J. Sperry and M. A. Brimble, Synlett, 2014, 25, 556-558. (IF = 2.7) https://doi.org/10.1055/s-0033-1340495

334. “An Important Side Reaction Using the Thiol, 3,6-Dioxa-1,8-octanedithiol (DODT), in 9-Fluorenylmethoxycarbonyl Based Solid Phase Peptide Synthesis” P. W. R. Harris, R. Kowalczyk, S.-H. Yang, G. M. Williams and M. A. Brimble, Journal of Peptide Science, 2014, 20, 186-190. (IF = 2.1) https://doi.org/10.1002/psc.2595

333. “Total Chemical Synthesis of an Orf Virus Protein, ORFV002, an Inhibitor of the Master Gene Regulator NF-B” S. J. Son, P. W. R. Harris, C. J. Squire, E. N. Baker and M. A. Brimble, Biopolymers (Peptide Science), 2014, 102, 137-144. (IF = 2.9) https://doi.org/10.1002/bip.22445

332. “Synthesis and Biological Evaluation of 7-Deoxy Analogues of the Human Rhinovirus 3C Protease Inhibitor Thysanone” K. Schünemann, D. P. Furkert, S. Connelly, J. D. Fraser, J. Sperry and M. A. Brimble, European Journal of Organic Chemistry, 2014, 122-128. (IF = 3.3) https://doi.org/10.1002/ejoc.201301515

331. “Synthesis of a Novel Polyaniline Glycopolymer and its Lectin Binding Studies” C. Wilcox, J. Jin, H. Charville, S. Swift, T. To, P. A. Kilmartin, C. W. Evans, R. Cooney and M. A. Brimble, Australian Journal of Chemistry, 2014, 67, 562-569. (IF = 1.9) https://doi.org/10.1071/CH13452

330. “Structure-Activity Relationships of the N-Terminus of Calcitonin Gene-related Peptide: Key Roles of Alanine-5 and Threonine-6 in Receptor Activation” D. L. Hay, P. W. R. Harris, R. Kowalczyk, M. A. Brimble, D. L. Rathbone, J. Barwell, A. C. Conner and D. R. Poyner, British Journal of Pharmacology, 2014, 171, 415-426. (IF = 5.1) https://dx.doi.org/10.1111%2Fbph.12464

329. “Synthesis of an Azido Precursor (2S,5R)-5-Hydroxylysine Using an Asymmetric Organocatalytic Chlorination/Reduction Sequence” M. Johannes and M. A. Brimble, Journal of Organic Chemistry, 2013, 79, 12809-12813. (IF = 4.6) https://doi.org/10.1021/jo402220s

328. “Synthesis of Leptosin, A Glycoside Isolated from Manuka Honey” H. R. M. Aitken, M. Johannes, K. M. Loomes and M. A. Brimble, Tetrahedron Letters, 2013, 54, 6916-6919. (IF = 2.7) https://doi.org/10.1016/j.tetlet.2013.10.042
• (Selected for “Front Cover”)

327. “Synthesis and Methemoglobinemia-inducing Properties of Analogues of para-aminopropiophenone Designed as Humane Rodenticides” D. Rennison, D. Conole, M. D. Tingle, J. Yang , C. T. Eason and M. A. Brimble, Bioorganic and Medicinal Chemistry Letters, 2013, 23, 6629-6635. (IF = 2.5) https://doi.org/10.1016/j.bmcl.2013.10.046

326. “Synthesis and Cytotoxicity of Pyranonaphthoquinone Natural Product Analogues Under Bioreductive Conditions” A. M. Heapy, A. V. Patterson, J. B. Smaill, S. M. F. Jamieson, C. P. Guise, J. Sperry, P. A. Hume, K. Rathwell and M. A. Brimble, Bioorganic and Medicinal Chemistry, 2013, 21, 7971-7980. (IF = 2.9) https://doi.org/10.1016/j.bmc.2013.09.052

325. “Total Synthesis of Virgatolide B” P. A. Hume, D. P. Furkert and M. A. Brimble, Organic Letters, 2013, 15, 4588-4591. (IF = 6.3) https://doi.org/10.1021/ol402191t

324. “Synthesis of Benzannulated Spiroacetals using Chiral Gold-Phosphine Complexes and Chiral Anions” R. Quach, D. P. Furkert and M. A. Brimble, Tetrahedron Letters, 2013, 54, 5865-5868. (IF = 2.7) https://doi.org/10.1016/j.tetlet.2013.08.077

323. “Direct Peptide Lipidation through Thiol-ene Coupling Enables Rapid Synthesis and Evaluation of Self-adjuvanting Vaccine Candidates” T. H. Wright, A. E. S. Brooks, A. J. Didsbury, G. M. Williams, P. W. R. Harris, R. P. Dunbar and M. A. Brimble, Angewandte Chemie International Edition, 2013, 52, 10616-10619. (IF = 13.7) https://doi.org/10.1002/anie.201305620

322. “Novel Preparation of Chiral alpha-Amino Acids using the Mitsunobu–Tsunoda Reaction” A. F. M. Noisier, C. S. Harris and M. A. Brimble, Chemical Communications, 2013, 49, 7744-7746. (IF = 6.4) https://doi.org/10.1039/C3CC44717K

321. “The Synthesis and Lectin-Binding Properties of Novel Mannose-Functionalised Polymers” H. Charville, J. Jin, C. W. Evans, M. A. Brimble and D. E. Williams, Royal Society of Chemistry Advances, 2013, 3, 15435-15441. (IF = 2.6) https://doi.org/10.1039/C3RA42781A

320. “Enantioselective Access to Benzannulated Spiroketals using a Chiral Sulfoxide Auxiliary” H. R. M. Aitken, D. P. Furkert, J. G. Hubert, J. M. Wood and M. A. Brimble, Organic and Biomolecular Chemistry, 2013, 11, 5147-5155. (IF = 3.6) https://doi.org/10.1039/C3OB41065J

319. “An Improved Method for the Synthesis of Lipopeptide TLR2-Agonists Using Click Chemistry” T. H. Wright, A. E. S. Brooks, A. J. Didsbury, J. D. McIntosh, K. Burkert, H. Yeung, G. M. Williams, P. R. Dunbar and M. A. Brimble, Synlett, 2013, 24, 1835-1841. (IF = 2.7) https://doi.org/10.1055/s-0033-1339349

318. “Prodrugs of N-Dicarboximide Derivatives of the Rat Selective Toxicant Norbormide” D. Rennison, O. Laita D. Conole, M. Jay-Smith, J. Knauf, S. Bova, M. Cavalli, B. Hopkins, D. S. Linthicum and M. A. Brimble, Bioorganic and Medicinal Chemistry, 2013, 21, 5886-5899. (IF = 2.9) https://doi.org/10.1016/j.bmc.2013.06.071

317. “Chemical Synthesis of a Masked Analogue of the Fish Antifreeze Potentiating Protein (AFPP)” S.-H. Yang, J. M. Wojnar, P. W. R. Harris, A. L. DeVries, C. W. Evans and M. A. Brimble, Organic and Biomolecular Chemistry, 2013, 11, 4935-4942. (IF = 3.6) https://doi.org/10.1039/C3OB41066H
• (Featured in Chemeurope and Bionity: http://www.chemeurope.com/en/news/144123/; www.bionity.com/en/news/144123/ and in “Chemistry World” Sept. 2013, p.29, http://www.rsc.org/chemistryworld/2013/07/antifreeze-fish-protein-synthesis)

316. “Synthesis of the Cysteine Protease Inhibitors CPI-2081a and CPI-2081b Using a Controlled SPPS Byproduct Forming Reaction” A. M. Heapy, M. Dragunow and M. A. Brimble, Synlett, 2013, 24, 1818-1824. (IF = 2.7) https://doi.org/10.1055/s-0033-1339347

315. “Grafting from Poly(3,4-ethylenedioxythiophene): A Simple Route to Versatile Electrically Addressable Surfaces” J. Malmström, M. K. Nieuwoudt, L. T. Strover, A. Hackett, O. Laita, M. A. Brimble, D. E. Williams and J. Travas-Sejdic, Macromolecules, 2013, 46, 4955-4965. (IF = 5.5) https://doi.org/10.1021/ma400803j

314. “Structure and Dynamics of Human Nedd4-1 WW3 in Complex with the alphaENaC PY Motif” R. Bobby, K. Medini, P. Neudecker, T. V. Lee, M. A. Brimble, F. J. McDonald, J. S. Lott and A. J. Dingley, Biochimica et Biophysica Acta – Proteins and Proteomics, 2013, 1834, 1632-1641. (IF = 3.6) https://doi.org/10.1016/j.bbapap.2013.04.031

313. “Synthesis of Stable Isotope Labelled Monolysyl Advanced Glycation Endproducts” T. M. Woods, G. S. Cooper and M. A. Brimble, Amino Acids, 2013, 45, 319-325. (IF = 3.9) https://doi.org/10.1007/s00726-013-1498-9

312. “One-Pot Synthesis of Water Soluble Iron Nanoparticles Using Rationally Designed Peptides and Ligand Release” S. Papst, S. Cheong, M. J. Banholzer, M. A. Brimble, D. E. Williams and R. D. Tilley, Chemical Communications, 2013, 49, 4540-4542. (IF = 6.4) https://doi.org/10.1039/C3CC41751D

311. “Synthesis of the Griseusin B Framework via a one-pot Annulation-Methylation-Double Deprotection-Spirocyclisation Sequence” B. J. Naysmith and M. A. Brimble, Organic Letters, 2013, 15, 2006-2009. (IF = 6.3) https://doi.org/10.1021/ol400686f

310. “Synthesis of the IGF-II-like Hormone Vesiculin using Regioselective Formation of Disulfide Bonds” G. M. Williams, G. J. S. Cooper, K. Lee, L. Whiting, and M. A. Brimble, Organic and Biomolecular Chemistry, 2013, 11, 3145-3150. (IF = 3.6) https://doi.org/10.1039/C3OB40322J

309. “Telomerase Inhibition Studies of Novel Spiroketal-Containing Rubromycin Derivatives” T.-Y. Yuen, Y.-P. Ng, F. C. F. Ip, J. L.-Y. Chen, D. J. Atkinson, J. Sperry, N. Y. Ip and M. A. Brimble, Australian Journal of Chemistry, 2013, 66, 530-533. (IF = 2.1) https://doi.org/10.1071/CH13035

308. “Total Synthesis of Chaetoquadrins H and I” U. B. Kim, A. F. Dalebrook, D. P. Furkert and M. A. Brimble, Synlett, 2013, 723-726. (IF = 2.7) https://doi.org/10.1055/s-0032-1318333

307. “A Comparison of Boc and Fmoc SPPS Strategies for the Preparation of C-Terminal Peptide alpha-Thioesters: NY-ESO-1 39Cys-68Ala-COSR” P. W. R. Harris and M. A. Brimble, Biopolymers (Peptide Science), 2013, 100, 356-365. (IF = 2.9) https://doi.org/10.1002/bip.22223

306. “Synthesis of a 6,6-Spiroketal Amino Acid and its Incorporation into a Peptide Turn Sequence using Solid Phase Peptide Synthesis” J. T. B. Kueh, K. W. Choi, G. M. Williams, K. Moehle, B. Bacsa, J. A. Robinson and M. A. Brimble, Chemistry – A European Journal, 2013, 19, 3807-3811. (IF = 5.8) https://doi.org/10.1002/chem.201204546

305. “Identification of Key Residues Involved in Adrenomedullin Binding to the AM1 Receptor” H. A. Watkins, M. Au, R. Bobby, J. K. Archibold, N. Abdul-Manan, J. M. Moore, M. J. Middleditch, G. M. Williams, M. A. Brimble, A. J. Dingley and D. L. Hay, British Journal of Pharmacology, 2013, 169, 143-155. (IF = 5.1) https://doi.org/10.1111/bph.12118

304. “Total Synthesis of Chaetoquadrins A-C” U. B. Kim, D. P. Furkert and M. A. Brimble, Organic Letters, 2013, 15, 658-661. (IF = 6.3) https://doi.org/10.1021/ol303482k

303. “A New Precursor for Conducting Polymer-based Brush Interfaces with Electroactivity in Aqueous Solution”
L. T. Strover, J. Malmström, O. Laita, J. Reynisson, N. Aydemir, M. K. Nieuwoudt, D. E. Williams, P. R. Dunbar, M. A. Brimble and J. Travas-Sejdic, Polymer, 2013, 54, 1305-1317. (IF = 3.4) https://doi.org/10.1016/j.polymer.2012.11.083

302. “DNA Adduct Formation of Mitomycin C. A Test Case for DFT Calculations on Model Systems” P. Hume, M. A. Brimble and J. Reynisson, Computational and Theoretical Chemistry, 2013, 1005, 9-15. (IF = 1.4) http://dx.doi.org/10.1016/j.comptc.2012.10.022

301. “Natural Product-inspired Pyranonaphthoquinone Inhibitors of Indoleamine 2,3-Dioxygenase (IDO-1)” D. J. A. Bridewell, J. Sperry, J. R. Smith, P. Kosim-Satyaputra, L.-M. Ching, J. F. Jamie and M. A. Brimble, Australian Journal of Chemistry, 2013, 66, 40-49. https://doi.org/10.1071/CH12393

300. “Synthesis and Self-Assembly of a Peptide-Amphiphile as a Drug Delivery Vehicle” S. J. Son, M. A. Brimble, S. Yang, P. W. R. Harris, T. Reddingius, B. W. Muir, O. E. Hutt, L. Waddington, J. Guan, and G. P. Savage, Australian Journal of Chemistry, 2013, 66, 23-29. (IF = 1.9) https://doi.org/10.1071/CH12347
• (Selected for “front cover”)

299. “Synthesis of the Tetracyclic Core of Berkelic Acid using Gold(I)-Catalyzed Hydroarylation and Oxidative Radical Cyclizations” M. A. Brimble, I. Haym, J. Sperry and D. P. Furkert, Organic Letters, 2012, 14, 5820-5823. (IF = 6.1) https://doi.org/10.1021/ol302536j

298. “Synthesis of the Peptaibol Framework of the Anticancer Agent Culicinin D: Stereochemical Assignment of the AHMOD Moiety” K.-Y. Hung, P. W. R. Harris and M. A. Brimble, Organic Letters, 2012, 14, 5784-5787. (IF = 6.1) https://doi.org/10.1021/ol302852q

297. “Synthesis of Monolysyl Advanced Glycation Endproducts and Their Incorporation into Collagen Model Peptides” T. Woods, M. Kamalov, P.W. R. Harris, G. J. S. Cooper and M. A. Brimble, Organic Letters, 2012, 14, 5740-5743. (IF = 6.1) https://doi.org/10.1021/ol302745f

296. “Total Synthesis of the Initially Reported and Revised Structures of the Neuroprotective Agent Palmyrolide A” A. D. Wadsworth, D. P. Furkert, J. Sperry and M. A. Brimble, Organic Letters, 2012, 14, 5374-5377. (IF = 6.1) https://doi.org/10.1021/ol3025956

295. “Total Synthesis of 7′,8′-Dihydroaigialospirol” T. Y. Yuen and M. A. Brimble, Organic Letters, 2012, 14, 5154-5157. (IF = 6.1) https://doi.org/10.1021/ol302498v

294. “How to Blast Osteoblasts? Novel Dicarba Analogues of Amylin-(1-8) to Treat Osteoporosis” R. Kowalczyk, M. A. Brimble, K. E. Callon, M.Watson and J. Cornish, Bioorganic and Medicinal Chemistry, 2012, 20, 6011-6018. (IF = 2.9) https://doi.org/10.1016/j.bmc.2012.08.053
• (highlighted in World Biomedical Frontiers<http://biomedfrontiers.org/ [ISSN: 2328-0166])

293. “A Single Pseudoproline and Microwave Solid Phase Peptide Synthesis Facilitates an Efficient Synthesis of Human Amylin 1-37″ P. W. R. Harris, R. Kowalczyk, D. Hay and M. A. Brimble, International Journal of Peptide Research and Therapeutics, 2013, 19, 147-155. (IF = 1.3) https://doi.org/10.1007/s10989-012-9325-9

292. “Synthesis of Multivalent Neoglycoconjugates of MUC1 by the Conjugation of Carbohydrate-centred, Triazole-linked Glycoclusters to MUC1 peptides using Click Chemistry” D. J. Lee, S.-H. Yang, G. M. Williams and M. A. Brimble, Journal of Organic Chemistry, 2012, 77, 7564-7571. (IF = 4.6) https://doi.org/10.1021/jo3013435

291. “A Slow Gradient Approach for the Purification of Synthetic Polypeptides by Reversed Phase High Performance Liquid Chromatography” P. W. R. Harris, D. J. Lee and M. A. Brimble, Journal of Peptide Science, 2012, 18, 549-555. (IF = 2.1) https://doi.org/10.1002/psc.2432

290. “Synthesis and SAR of a Library of Cell-Permeable Biotin-R8ERY* Peptidomimetics Inhibiting alpha4 beta7 Integrin Mediated Adhesion of TK-1 Cells to MAdCAM-1-Fc” S. Papst, A. F. M. Noisier, M. A. Brimble, Y. Yang, Y.-C. Chan and G. W. Krissansen, Australian Journal of Chemistry, 2012, 65, 1349-1358. (IF = 1.9) http://dx.doi.org/10.1071/CH12227

289. “Synthesis and Biological Evaluation of Tyrosine Modified Analogues of the alpha4 beta7 Integrin Inhibitor Biotin-R8ERY” S. Papst, A. F. M. Noisier, M. A. Brimble, Y. Yang and G. W. Krissansen, Bioorganic and Medicinal Chemistry, 2012, 20, 5139-5149. (IF = 2.9) https://doi.org/10.1016/j.bmc.2012.07.010

288. “Synthesis of the All-L Cyclopeptides Versicoloritides A, B and C” H. Kaur, A. M. Heapy and M. A. Brimble, Synlett, 2012, 23, 2284-2288. (IF = 2.7) https://doi.org/10.1055/s-0032-1316994

287. “A Simple Solid Phase, Peptide-based Fluorescent Assay for the Efficient and Universal Screening of HRV 3C Protease Inhibitors” K. Schünemann, S. Connelly, R. Kowalczyk, J. Sperry, I. A. Wilson, J. D. Fraser and M. A. Brimble, Bioorganic and Medicinal Chemistry Letters, 2012, 22, 5018-5024. (IF = 2.5) https://doi.org/10.1016/j.bmcl.2012.06.015

286. “A Tandem Diels-Alder/Mannich Approach to the Synthesis of AE and ABE Ring Analogues of Delphinium Alkaloids” K. J. Goodall, M. A. Brimble and D. Barker, Tetrahedron, 2012, 68, 5759-5778. (IF = 2.8) https://doi.org/10.1016/j.tet.2012.05.037

285. “Design and Synthesis of Prodrugs of the Rat Selective Toxicant Norbormide” D. Rennison, O. Laita, S. Bova, M. Cavalli, B. Hopkins, D. S. Linthicum and M. A. Brimble, Bioorganic and Medicinal Chemistry, 2012, 20, 3997-4011. (IF = 2.9) https://doi.org/10.1016/j.bmc.2012.05.014

284. “Access to 2-Alkyl Chromanones via a Conjugate Addition Approach” L. A. Stubbing, F. F. Li, D.P. Furkert, V. E. Caprio and M. A. Brimble, Tetrahedron, 2012, 68, 6948-6956. (IF = 2.8) https://doi.org/10.1016/j.tet.2012.05.115

283. “Determination of pKa and Forced Degradation of the Indoloquinoline Antimalarial Compound Cryptolepine
Hydrochloride” N. Kuntworbe, M. A. Brimble, R. G. Alany and R. Al-Kassas, Pharmaceutical Development and Technology, 2013, 18, 866-876. (IF = 1.3) https://doi.org/10.3109/10837450.2012.668554

281. “Regioselective Iridium(I)-Catalysed Remote Borylation of Oxygenated Naphthalenes” P. Hume, D. P. Furkert and M.A. Brimble, Tetrahedron Letters, 2012, 53, 3771-3773. (IF = 2.7) https://doi.org/10.1016/j.tetlet.2012.05.040

280. “Novel Phosphopeptides as Surface-Active Agents in Iron Nanoparticle Synthesis” R. Peltier, W. R. Siah, G. V. M. Williams, M. A. Brimble, R. D. Tilley and D. E. Williams, Australian Journal of Chemistry, 2012, 65, 680-685. (IF = 1.9) https://doi.org/10.1071/CH12168

279. “A Highly Conserved Tryptophan in the N-Terminal Variable Domain Regulates Rate of Disulfide Bond Formation and Oligomeric Assembly of Adiponectin” M. Radjainia, B. Huang, B. Bai, M. Schmitz, S. H. Yang, P. W. R. Harris, M. D. W. Griffin, M. A. Brimble, Y. Wang, and A. M. Mitra, FEBS Journal, 2012, 279, 2495-2507. (IF = 4.3) https://doi.org/10.1111/j.1742-4658.2012.08630.x

278. “A Method for the Generation of Pam2Cys-Based Lipopeptide Mimics via CuAAC Click Chemistry” H. Yeung, D. J. Lee, G. M. Williams, P. W. R. Harris and M. A. Brimble, Synlett, 2012, 23, 1617-1620. (IF = 2.7) https://doi.org/10.1055/s-0031-1291148

277. “Tyrosine Modified Analogues of the alpha4 beta7 Integrin Inhibitor Biotin-R8ERY Prepared via Click Chemistry: Synthesis and Biological Evaluation” S. Papst, A. Noisier, M. A. Brimble, Y. Yang and G. W. Krissansen, Bioorganic and Medicinal Chemistry, 2012, 20, 2638-2644. (IF = 2.9) https://doi.org/10.1016/j.bmc.2012.02.035
• (Selected for inclusion on Global Medical Discovery Website; http://globalmedicaldiscovery.com)

276. “Synthesis and Evaluation of Disulfide Bond Mimetics of Amylin-(1-8) as Agents to Treat Osteoporosis” R. Kowalczyk, P. W. R. Harris, M. A. Brimble, K. E. Callon, M. Watson and J. Cornish, Bioorganic and Medicinal Chemistry, 2012, 20, 2661-2668. (IF = 2.9) https://doi.org/10.1016/j.bmc.2012.02.030

275. “The Bioreductive Alkylation of DNA by Kalafungin. A Theoretical Investigation” P. Hume, J. Reynisson and M. A. Brimble, Australian Journal of Chemistry, 2012, 65, 402-408. (IF = 1.9) https://doi.org/10.1071/CH12018

274. “A Convergent Synthesis of the 2-Formylpyrrole Spiroketal Natural Product Acortatarin A” H. M. Geng, J. L.-Y. Chen, D. P. Furkert, S. Jiang and M. A. Brimble, Synlett, 2012, 23, 855-858. (IF = 2.7) https://doi.org/10.1055/s-0031-1290508

273. “Synthesis and anti-Helicobacter pylori Activity of Analogues of Spirolaxine Methyl Ether” I. Dimitrov, D. P. Furkert, J. D. Fraser, F. J. Radcliff, O. Finch and M. A. Brimble, MedChemComm, 2012, 3, 944-949. (IF = 2.7) https://doi.org/10.1039/C2MD00314G
• (Invited paper for Special Issue on Natural Products and selected for Front Cover)

272. “Synthesis of a Dicarba Analogue of Human beta-Defensin-1 using a Combined Ring Closing Metathesis-Native Chemical Ligation Strategy” A. M. Heapy, G. M. Williams, J. D. Fraser and M. A. Brimble, Organic Letters, 2012, 14, 878-881. (IF = 6.1) https://doi.org/10.1021/ol203407z

271. “Metabolic and Behavioural Adaptations During Early Development of the Antarctic Silverfish, Pleuragramma Antarcticum” C. Evans, D. E. Williams, M. Vacchi, M. A. Brimble and A. L. DeVries, Polar Biology, 2012, 35, 891-898. (IF = 1.7) http://dx.doi.org/10.1007/s00300-011-1134-7

270. “An Efficient Synthesis of 3-Alkyl-1,5,3-dioxazepanes and Their Use as Electrophiles in Double Mannich Reactions” K. Sparrow, D. Barker and M.A. Brimble, Tetrahedron, 2012, 68, 1017-1028. (IF = 2.8) https://doi.org/10.1016/j.tet.2011.11.090

269. “Enantioselective Synthesis of C-Linked Spiroacetal-Triazoles as Privileged Natural Product-like Scaffolds” J. T. B. Kueh, K. W. Choi and M. A. Brimble, Organic and Biomolecular Chemistry, 2012, 10, 5993-6002. (IF = 3.6) https://doi.org/10.1039/C2OB06802H
• (Invited paper for Special Issue to celebrate 10th Anniversary of OBC)

268. “Synthesis of the Antifungal Cyclic Peptides Tunicyclins C and D” H. Kaur, A. M. Heapy and M. A. Brimble, Synlett, 2012, 23, 275-277. (IF = 2.7) https://doi.org/10.1055/s-0031-1290071

267. “Formal Synthesis of Berkelic Acid: A Lesson in alpha-Alkylation Chemistry” M. McLeod, Z. Wilson and M. A. Brimble, Journal of Organic Chemistry, 2012, 77, 400-406. (IF = 4.6) https://doi.org/10.1021/jo201988m

266. “Total Synthesis of Danshenspiroketallactone” D. F. Chorley, J. L.-Y. Chen, D. P. Furkert, J. Sperry and M. A. Brimble, Synlett, 2012, 23, 128-130. (IF = 2.7) https://doi.org/10.1055/s-0031-1290082

265. “The Chemical Synthesis of the Collagenous Domain of the Hormone Adiponectin” P. W. H. Harris and M. A. Brimble, International Journal of Peptide Research and Therapeutics, 2012, 18, 63-70. (IF = 1.3) https://doi.org/10.1007/s10989-011-9279-3

264. “Synthesis and Recycling of Antifreeze Glycoproteins in Polar Fishes” C. W. Evans, L. Hellman, M. Middleditch, J. M. Wojnar, M. A. Brimble and A. L. DeVries, Antarctic Science, 2012, 24, 259-268. (IF = 1.6) https://doi.org/10.1017/S0954102012000119

263. “Synthesis of the Bis-Spiroacetal Core of the Antimitotic Agent Spirastrellolide” J. L.-Y. Chen and M. A. Brimble, Journal of Organic Chemistry, 2011, 76, 9417-9428. (IF = 4.6) https://doi.org/10.1021/jo201729t

262. “Synthesis of a NDPK Phosphocarrier Domain Peptide Containing a Triazolylalanine Analogue of Phosphohistidine Using Click Chemistry” S.-H. Yang, D.-J. Lee and M. A. Brimble, Organic Letters, 2011, 13, 5604-5607. (IF = 5.9) https://doi.org/10.1021/ol202333u

261. “An Enantioselective Formal Synthesis of Berkelic Acid” M. C. McLeod, Z. E. Wilson and M. A. Brimble, Organic Letters, 2011, 13, 5382-5385. (IF = 5.9) https://doi.org/10.1021/ol202265g

260. “An Improved Procedure for the Preparation of Aminomethyl Polystyrene Resin and its use in Solid Phase (Peptide) Synthesis” P. W. R. Harris, S.-H. Yang and M. A. Brimble, Tetrahedron Letters, 2011, 52, 6024-6026. (IF = 2.7) https://doi.org/10.1016/j.tetlet.2011.09.010

259. “The Translocator Protein (Peripheral Benzodiazepine Receptor) Mediates Rat-selective Activation of the Mitochondrial Permeability Transition by Norbormide” A. Zulian, J. Šileikytė, V. Petronilli, S. Bova, F. Dabbeni-Sala, G. Cargnelli, D. Rennison, M. A. Brimble, B. Hopkins, P. Bernardi and F. Ricchelli, Biochimica et Biophysica Acta – Bioenergetics, 2011, 1807, 1600-1605. (IF = 4.8) https://doi.org/10.1016/j.bbabio.2011.08.007

258. “The Enantioselective Synthesis of Tetracyclic Methyllycaconitine Analogues” K. Sparrow, D. Barker and M. A. Brimble, Tetrahedron, 2011, 67, 7989-7999. (IF = 2.8) https://doi.org/10.1016/j.tet.2011.08.026

257. “Gold(I)-Catalysed Intramolecular Hydroamination of alpha-Quaternary Alkynes: Synthetic Studies Towards Spiroimine Marine Toxins” Y. C. Zhang, D. P. Furkert, S. Gueret, F. Lombard and M. A. Brimble, Tetrahedron Letters, 2011, 4896-4898. (IF = 2.7) https://doi.org/10.1016/j.tetlet.2011.07.048

256. “Total Synthesis of Paecilospirone” T.-Y. Yuen, S.-H. Yang and M. A. Brimble, Angewandte Chemie International Edition, 2011, 50, 8350-8353. (IF = 13.5) http://dx.doi.org/10.1002/anie.201103117

255. “Enantioselective Synthesis of Pyranonaphthoquinone Antibiotics using a CBS Reduction/Cross-Metathesis/oxa-Michael Strategy” P. A. Hume, J. Sperry and M. A. Brimble, Organic and Biomolecular Chemistry, 2011, 9, 5423-5430. (IF = 3.7) http://dx.doi.org/10.1039/c1ob05595j

254. “A Flexible Approach to 6,5-Benzannulated Spiroketals” Z. E. Wilson, J. G. Hubert and M. A. Brimble, European Journal of Organic Chemistry, 2011, 28, 3938-3945. (IF = 3.3) http://dx.doi.org/10.1002/ejoc.201100345
• (Invited Paper for Special Issue to Celebrate International Year of Chemistry”)

253. “Efficient Synthesis of the Spiroacetal Core of Paecilospirone via Oxidative Radical Cyclisation” M. Jay-Smith, D. P. Furkert, J. Sperry and M. A. Brimble, Synlett, 2011, 1395-1398. (IF = 2.7) http://dx.doi.org/10.1055/s-0030-1260564

252. “Synthesis of Benzannulated Spiroketals using an Oxidative Radical Cyclization” J. Sperry, Y.-C. Liu, Z. E. Wilson, J. G. Hubert and M. A. Brimble, Synthesis, 2011, 1383-1398. (IF = 2.5) http://dx.doi.org/10.1055/s-0030-1259981

251. “Synthesis of an Isotopically-Labelled Antarctic Fish Antifreeze Glycoprotein Probe” J. M. Wojnar, C. W. Evans, A. L. DeVries and M. A. Brimble, Australian Journal of Chemistry, 2011, 64, 723-731.(IF = 1.9) https://doi.org/10.1071/CH10464
• (Invited paper for Special Issue on Women in Science to celebrate International Year of Chemistry and 100th Anniversary of Nobel Prize being awarded to Marie Curie)

250. “Synthesis of MUC1 Neoglycopeptides using Efficient Microwave-Enhanced Chaotrope-Assisted Click Chemistry” D. J. Lee, P. W. R. Harris and M. A. Brimble, Organic and Biomolecular Chemistry, 2011, 9, 1621-1626. (IF = 3.6) https://doi.org/10.1039/C0OB01043J

249. “Synthesis and Assignment of Stereochemistry of the Antibacterial Cyclic Peptide Xenamatide” K.-Y. Hung, P. W. R. Harris, A. M. Heapy and M. A. Brimble, Organic and Biomolecular Chemistry, 2011, 9, 236-242. (IF = 3.6) https://doi.org/10.1039/C0OB00315H

248. “A Convergent Synthesis of the [4.4]-Spiroacetal-γ-lactones Cephalosporolides E and F” M. A. Brimble, O. C. Finch, A. M. Heapy, J. D. Fraser, D. P. Furkert and P. D. O’Connor, Tetrahedron, 2011, 67, 995-1001. (IF = 2.8) https://doi.org/10.1016/j.tet.2010.11.107

247. “Synthesis of Benzotriazole Analogues of the Helicobactericidal Agents CJ-13,015, CJ-13,102, CJ-13,108 and CJ-13,104 using a Regioselective 1,3-Dipolar Cycloaddition” D. J. Atkinson, J. Sperry and M. A. Brimble, Synlett, 2011, 99-103. (IF = 2.7) http://dx.doi.org/10.1055/s-0030-1259081

246. “How do Antarctic Notothenioid Fishes Cope with Internal Ice? A Novel Function for Antifreeze Glycoproteins” C. W. Evans, V. Gubala, R. Nooney, D. E. Williams, M. A. Brimble and A. L. De Vries, Antarctic Science, 2011, 23, 57-64. http://dx.doi.org/10.1017/S0954102010000635
• (Selected to the Faculty of 1000 http://f1000.com/9089956) (IF = 1.6)

245. “Synthesis of Methyl N-Boc-(2S, 4R)-4-Methylpipecolate” K. Y. Hung, P. W. R. Harris and M. A. Brimble,
Journal of Organic Chemistry, 2010, 75, 8728-8731. (IF = 4.6) https://doi.org/10.1021/jo102038q

244. “Synthesis of a Functionalised 7,6-Bicyclic Spiroimine Ring Fragment of the Spirolides” S. M. Gueret, D. P. Furkert and M. A. Brimble, Organic Letters, 2010, 12, 5226-5229. (IF = 5.9) https://doi.org/10.1021/ol102525w

243. “Stereoselective Synthesis of 4-Substituted 4-Hydroxypiperidines via Epoxidation-Ring Opening of 4-Methylenepiperidines” V. A. McKay, S. J. Thompson, P. M. Tran, K. J. Goodall, M. A. Brimble and D. Barker, Synlett, 2010, 17, 2631-2635. (IF = 2.7) http://dx.doi.org/10.1055/s-0030-1258778

242. “Hetero-Directed Reverse Wacker Oxidations. Synthesis of the Reported Structure of (–)-Herbaric Acid” P. J. Choi, J. Sperry and M. A. Brimble, Journal of Organic Chemistry, 2010, 75, 7388-7392. (IF = 4.6) https://doi.org/10.1021/jo1016585

241. “A Double Mannich Approach to the Synthesis of Substituted Piperidones – Application to the Synthesis of Substituted E-ring Analogues of Methyllycaconitine” Y. Chan, J. Balle, J. K. Sparrow, P. D. W. Boyd, M. A. Brimble, D. Barker, Tetrahedron, 2010, 66, 7179-7191. (IF = 2.8) https://doi.org/10.1016/j.tet.2010.06.084

240. “Growth Habit Modification of Ice Crystals using Antifreeze Glycoprotein (AFGP) Analogues” R. Peltier, C. W. Evans, A. L. DeVries, M. A. Brimble, A. J. Dingley and D. E. Williams, Crystal Growth and Design, 2010, 10, 5066-5077. (IF = 4.72) https://doi.org/10.1021/cg1005083

239. “Synthesis of the Pyranonaphthoquinones Dehydroherbarin, (+)-Astropaquinone B and (+)-Astropaquinone C en route to Ascomycones A and B” A. Wadsworth, J. Sperry and M. A. Brimble, Synthesis, 2010, 2604-2608. (IF = 2.5) http://dx.doi.org/10.1055/s-0029-1218832

238. “Synthesis of the FG Ring Fragment of Pectenotoxins 1-9” A. Heapy and M. A. Brimble, Tetrahedron, 2010, 66, 5424-5431. (IF = 2.8) https://doi.org/10.1016/j.tet.2010.05.027

237. “Synthesis of the Bis-Spiroacetal C25–C40 Moiety of the Antimitotic Agent Spirastrellolide B using a Bis-Dithiane Deprotection/Spiroacetalisation Sequence” J. L.-Y. Chen and M. A. Brimble, Chemical Communications, 2010, 46, 3967-3969. (IF = 5.8) https://doi.org/10.1039/C0CC00056F

236. “Synthesis of Triazole Analogues of the Nanaomycin Antibiotics using ‘Click Chemistry’ ” K. Rathwell, J. Sperry and M. A. Brimble, Tetrahedron, 2010, 66, 4002-4009. (IF = 2.8) https://doi.org/10.1016/j.tet.2010.04.048

235. “A Flexible Asymmetric Synthesis of the Tetracyclic Core of Berkelic Acid using a Horner-Wadsworth-Emmons/oxa-Michael Cascade” Z. E. Wilson and M. A. Brimble, Organic and Biomolecular Chemistry, 2010, 8, 1284-1286. (IF = 3.7) https://doi.org/10.1039/B927219B

234. “Total Synthesis and Absolute Configuration of (-)-Berkeleyamide A” J. Sperry, E. B. J. Harris and M. A. Brimble, Organic Letters, 2010, 12, 420-423. (IF = 5.3) https://doi.org/10.1021/ol902525k

233. “Metal Binding Studies Using Spiroacetal Crown Ethers” M. Nikac, M. A. Brimble, R. L. Crumbie and T. D. Bailey, Tetrahedron Letters, 2010, 51, 1072-1074. (IF = 2.7) https://doi.org/10.1016/j.tetlet.2009.12.110

232. “Improved Synthesis of the Benzyne Precursor 2-(Trimethylsilyl)phenyl Trifluoromethanesulfonate” D. J. Atkinson, J. Sperry and M. A. Brimble, Synthesis, 2010, 911-913. (IF = 2.5) https://doi.org/10.1016/10.1055/s-0029-1218631

231. “Microwave Assisted Synthesis of Fluorescein-Labelled GalNAc1-O-Ser/Thr (Tn) Glycopeptides as Immunological Probes” D. J. Lee, P. W. R. Harris, R. Kowalczyk, P. R. Dunbar and M. A. Brimble, Synthesis, 2010, 763-769. (IF = 2.5) http://dx.doi.org/10.1055/s-0029-1218635

230. “Towards the Total Chemical Synthesis of the Cancer Protein NY-ESO-1” P. W. R. Harris and M. A. Brimble, Biopolymers (Peptide Science), 2010, 94, 542-550. (IF = 2.9) https://doi.org/10.1002/bip.21351
• (Invited paper for Special Issue of Peptide Science dedicated to Professor Steve Kent)

229. “A One-pot Approach to Neoglycopeptides using Orthogonal Native Chemical Ligation and Click Chemistry” D. J. Lee, K. Mandal, P. W. R. Harris, M. A. Brimble and S. B. H. Kent, Organic Letters, 2009, 11, 5270-5273. (IF = 5.4) https://doi.org/10.1021/ol902131n

228. “Synthesis and Reactivity of beta-Methoxymethyl Enecarbamates” P. D. O’Connor, M. G. Marino, S. M. Gueret and M. A. Brimble, Journal of Organic Chemistry, 2009, 74, 8893-8896. (IF = 4.805) https://doi.org/10.1021/jo901992z

227. “Pyranonaphthoquinone Derivatives of Eleutherin, Ventiloquinone L, Thysanone and Nanaomycin A Possessing a Diverse Topoisomerase II Inhibition and Cytotoxicity Spectrum” J. Sperry, I. Loreno-Castrillejo, M. A. Brimble and F. Machin, Bioorganic and Medicinal Chemistry, 2009, 17, 7131-7137. https://doi.org/10.1016/j.bmc.2009.08.064

226. “An Efficient Formal Synthesis of the Human Telomerase Inhibitor (±)-γ-Rubromycin” D. C. K. Rathwell, S.-H. Yang, K.Y. Tsang and M.A. Brimble, Angewandte Chemie International Edition, 2009, 48, 7996-8000. https://doi.org/10.1002/anie.200903316
• (Selected for “frontispiece” and as a very important paper (VIP) -only 5% of papers selected as VIP papers)

225. “Synthesis of an Arginine Tagged [Cys155-Arg180] Fragment of NY-ESO-1: Elimination of an Undesired By-product using “In House” Resins” P. W. R. Harris and M. A. Brimble, Synthesis, 2009, 3460-3466. https://doi.org/10.1055/s-0029-1216952

224. “A Novel Approach to Monobenzannulated Spiroketals Using Styrene in the Kulinkovich Reaction” I. Haym and M. A. Brimble, Synlett, 2009, 2315-2319. https://doi.org/10.1055/s-0029-1217708

223. “Synthesis of (+)-Wine Lactone and its Analogues by a Diels-Alder Approach” P. D. O’Connor, U. B. Kim and M. A. Brimble, European Journal of Organic Chemistry, 2009, 26, 4405-4411. https://doi.org/10.1002/ejoc.200900486
• (Selected for “front cover”)

222. “Synthesis of Fish Antifreeze Neoglycopeptides Using Microwave-Assisted “Click Chemistry” N. Miller, G. M. Williams and M. A. Brimble, Organic Letters, 2009, 11, 2409-2412. https://doi.org/10.1021/ol9005536

221. “Biomimetic Studies Towards the Cardinalins: Synthesis of (+)-Ventiloquinone L and an Unusual Dimerisation” J. Sperry, J. J. P. Sejberg, F. M. Stiemke and M. A. Brimble, Organic and Biomolecular Chemistry, 2009, 7, 2599-2603. https://doi.org/10.1039/B905077A

220. “Enantioselective Synthesis of the 3C-Protease Inhibitor (–)-Thysanone using a Staunton-Weinreb Annulation Strategy” J. Sperry, T. Y. Yuen and M. A. Brimble, Synthesis, 2009, 2561-2569. https://doi.org/10.1055/s-0029-1217390

219. “Influence of alpha-Methyl Substitution of Proline-based Organocatalysts on the Asymmetric alpha-Oxidation of Aldehydes” S. -T. Tong, M. A. Brimble and D. Barker, Tetrahedron, 2009, 65, 4801-4807. https://doi.org/10.1016/j.tet.2009.04.060

218. “Stability of 5(6)-Carboxyfluorescein in Microwave Assisted Synthesis of Fluorescein-Labelled O-Dimannosylated Peptides” R. Kowalczyk, P. W. R. Harris, R. P. Dunbar and M. A. Brimble, Synthesis, 2009, 2210-2222. http://dx.doi.org/10.1055/s-0029-1216820

217. “Synthetic Studies Towards the Anti-inflammatory Agent, Oleocanthal using a Johnson–Claisen (orthoester) Rearrangement Strategy,” J. -T. B. Kueh, P. D. O’Connor, H. Hügel and M. A. Brimble, Archive for Organic Chemistry (ARKIVOC), 2009, (vii), 58-71. http://dx.doi.org/10.3998/ark.5550190.0010.706

216. “Use of Click Chemistry for the Synthesis of Tetrazole-Containing Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)” K.-Y. Hung, P. W. R. Harris and M. A. Brimble, Synlett, 2009, 1233-1236. http://dx.doi.org/10.1055/s-0028-1088128

215. “Synthesis of AE and BE Ring Analogues of the Alkaloid Methyllycaconitine” H. Guthmann, D. Conole, E. Wright, K. Koerber, D. Barker and M. A. Brimble, European Journal of Organic Chemistry, 2009, 1944-1960. https://doi.org/10.1002/ejoc.200900030

214. “Synthesis of 6,6-Bisbenzannulated Spiroketals Related to the Rubromycins Using a Double Intramolecular Hetero-Michael Addition (DIHMA)” P. Choi, D. C. K. Rathwell and M. A. Brimble, Tetrahedron Letters, 2009, 50, 3245-3248. https://doi.org/10.1016/j.tetlet.2009.02.030
• (Invited Article for the special edition to mark the 50th Golden Anniversary of Tetrahedron Letters).

213. “A Facile Cross Metathesis-Radical Cyclisation Approach to Monobenzannulated Spiroketals” Y.-C. Liu, J. Sperry, D. C. K. Rathwell and M. A. Brimble, Synlett, 2009, 793-797. https://doi.org/10.1055/s-0028-1087942

212. “Synthesis of Enantiopure Bicyclic alpha,alpha-Disubstituted Spirolactams via Asymmetric Birch Reductive Alkylation” S. M. Guéret, P. D. O’Connor and M. A. Brimble, Organic Letters, 2009, 11, 963-966. https://doi.org/10.1021/ol8029017

211. “Synthesis of Spiroacetal-Nucleosides as Privileged Natural Product-like Scaffolds” K. W. Choi and M. A. Brimble, Organic and Biomolecular Chemistry, 2009, 7, 1424-1436. https://doi.org/10.1039/B818314G

210. “A Novel Approach to the CDE Ring System of Pectenotoxin-4 Triggered by VO(acac)2 Induced Epoxy-Acetalization” S. Carley and M. A. Brimble, Organic Letters, 2009, 11, 563-566. https://doi.org/10.1021/ol8025457

209. “In vitro Metabolism of Norbormide in Rat, Mouse and Guinea Pig Liver Preparations” S. Ravindran, B. Hopkins, S. Bova, D. Rennison, M. A. Brimble and M. Tingle, Environmental Toxicology and Pharmacology, 2009, 27, 144-148. https://doi.org/10.1016/j.etap.2008.09.007

208. “NNZ-2566: A Gly–Pro–Glu Analogue With Neuroprotective Efficacy in a Rat Model of Acute Focal Stroke” M. J. Bickerdike, G. B. Thomas, D. C. Batchelor, E. S. Sirmianne, W. Leong, H. Lai, F. Sieg, J. Wen, M. A. Brimble, P. W. R. Harris and P. D. Gluckman, Journal of the Neurological Sciences, 2009, 278, 85-90. https://doi.org/10.1016/j.jns.2008.12.003

207. “3-Allyl-2-hydroxy-5,6,8-trimethoxynaphthalene-1,4-dione” D. C. Rathwell, K. Y. Tsang, K. W. Choi, P. D. W. Boyd, and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O1929. https://dx.doi.org/10.1107%2FS1600536808028432

206. “Enantioselective Synthesis of the Dimeric Pyranonaphthoquinone Core of the Cardinalins Using a Late-Stage Homocoupling Strategy” J. Sperry, J. S. Gibson, J. J. P. Sejberg and M. A. Brimble, Organic and Biomolecular Chemistry, 2008, 6, 4261-4270. https://doi.org/10.1039/B813605J

205. “Diastereoselective Synthesis of Substituted 4-Piperidones and 4-Piperidols Using a Double Mannich Reaction” Y. Chan, H. Guthmann, M. A. Brimble and D. Barker, Synlett, 2008, 2601-2604. https://doi.org/10.1055/s-0028-1083522

204. “The Synthesis of Phosphopeptides Using Microwave-assisted Solid Phase Peptide Synthesis” P. W. R. Harris, G. M. Williams, P. Shepherd and M. A. Brimble, International Journal of Peptide Research and Therapeutics, 2008, 14, 387-392. https://doi.org/10.1007/s10989-008-9149-9

203. “racemic-N-(3-hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide” S. T. Tong, D. Barker, K. W. Choi, P. D. W. Boyd and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O1990. https://dx.doi.org/10.1107%2FS1600536808028948

202. “racemic-2′-Phenylcyclohexanespiro-4′-(azepano[1,2-b]isoxazolidine)” D. Crimmins, K. W. Choi, P. D. W. Boyd, and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O1535. http://dx.doi.org/10.1107/S1600536808021867

201. “A Facile Synthesis of a Spironitrone and a Study of its Cycloaddition and Nucleophilic Addition Reactions” D. Crimmins, I. Dimitrov, P. D. O’Connor, V. Caprio and M. A. Brimble, Synthesis, 2008, 3319-3325. http://dx.doi.org/10.1055/s-0028-1083151

200. “Synthesis of Spiroacetal-Triazoles as Privileged Natural Product-Like Scaffolds Using ‘Click Chemistry’” K. W. Choi and M. A. Brimble, Organic and Biomolecular Chemistry, 2008, 6, 3518-3526. https://doi.org/10.1039/B808454H
• (Invited paper for special issue to honour Professor Andrew Holmes’s 65th birthday, selected for “front cover”)

199. “An Efficient Enantioselective Synthesis of the 3C Protease Inhibitor (–)-Thysanone” J. Sperry and M. A. Brimble, Synlett, 2008, 1910-1912. http://dx.doi.org/10.1055/s-2008-1078590

198. “(1R,6R)-1-Methyl-8-azaspiro[5.6]dodecan-7-one” S. M. Guéret, K. W. Choi, P. D. O’Connor, P. D. W. Boyd and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O1151. http://dx.doi.org/10.1107/S1600536808015158

197. “Buchwald-Hartwig Mono-N-arylation of 2,6-Dihaloisonicotinic Acid Derivatives: A Convenient Desymmetrization Method” A. V. Lorimer, P. D. O’Connor and M. A. Brimble, Synthesis, 2008, 2764-2770. http://dx.doi.org/10.1055/s-2008-1067208

196. “anti-Helicobacter pylori Activity of Derivatives of the Phthalide-Containing Antibacterial Agents Spirolaxane Methyl Ether, CJ-12,954, CJ-13,013, CJ-13,102, CJ-13,104, CJ-13,108 and CJ-13,015” F. J. Radcliff, J. D. Fraser, Z. E. Wilson, A. M. Heapy, J. E. Robinson, C. J. Bryant, C. L. Flowers and M. A. Brimble, Bioorganic and Medicinal Chemistry, 2008, 16, 6179-6185. https://doi.org/10.1016/j.bmc.2008.04.037

195. “(1R,1´R,3S,3´S)-5,5´,10,10´-Tetramethoxy-1,1´,3,3´-tetramethyl-3,3´,4,4´-terahydro-1H,1´H-8,8´-bibenzo[g]isochromene” J. J. P. Sejberg, J., Sperry, K. W. Choi, P. D. W. Boyd and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O758. https://doi.org/10.1107/s1600536808007599

194. “racemic-1-{8´-(tert-Butyldiphenylsilyloxymethyl)-1´,7´-dioxaspiro[5.5]undecan-2´-yl}uridine” K. W. Choi, M. A. Brimble and T. Groutso, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O715. https://dx.doi.org/10.1107%2FS1600536808006727

193. “Novel Use of N-Carboalkoxy alpha,beta-Unsaturated Iminium Ions as Dienophiles in Diels-Alder Reactions” P. D. O’Connor, K. Koerber and M. A. Brimble, Synlett, 2008, 1036-1038. http://dx.doi.org/10.1055/s-2008-1072658

192. “A Facile Enantioselective Synthesis of the Dimeric Pyranonaphthoquinone Core of the Cardinalins” M. A. Brimble, J. S. Gibson, J. J. P. Sejberg and J. Sperry, Synlett, 2008, 867-870. http://dx.doi.org/10.1055/s-2008-1042896

191. “1H and 13C NMR Spectra for C-6 and C-9 Substituted 3-Azabicyclo[3.3.1]nonanes” K. J. Goodall, M. A. Brimble and D. Barker, Magnetic Resonance in Chemistry, 2008, 46, 75-79. http://dx.doi.org/10.1002/mrc.2100

190. “An Approach to an Enantioselective Synthesis of Crisamicin A via a Novel Double Hauser-Kraus Annulation Strategy” O. Andrey, J. Sperry, U. S. Larsen and M. A. Brimble, Tetrahedron, 2008, 64, 3912-3927. https://doi.org/10.1016/j.tet.2008.02.065

189. “Synthesis of a C8 Oxygenated Pyranonaphthoquinone: A Useful Precursor to Dimeric Pyranonaphthoquinones” P. Bachu, M. A. Brimble and J. Sperry, Tetrahedron, 2008, 64, 3343-3350. https://doi.org/10.1016/j.tet.2008.01.135

188. “Chemoenzymatic Synthesis of Deoxy Analogues of the DNA Topoisomerase II Inhibitor Eleutherin and the 3C-Protease Inhibitor Thysanone” P. Bachu, J. Sperry and M. A. Brimble, Tetrahedron, 2008, 64, 4827-4834. https://doi.org/10.1016/j.tet.2008.01.112
• (Invited Article for Tetrahedron Symposia-in-Print – “Natural Products Synthesis”)

187. “Synthesis of Fluorescein-Labelled O-Mannosylated Peptides as Components for Synthetic Vaccines: Comparison of Two Synthetic Strategies” M. A. Brimble, R. Kowalczyk, P. W. R. Harris, P. R. Dunbar and V. J. Muir, Organic and Biomolecular Chemistry, 2008 6, 112-121. https://doi.org/10.1039/b712926b

186. “Use of (S)-5-(2-Methylpyrrolidin-2-yl)-1H-tetrazole as a Novel and Enantioselective Organocatalyst for the Aldol Reaction” S.-T. Tong, P. W. R. Harris, D. Barker and M. A. Brimble, European Journal of Organic Chemistry, 2008, 164-170. https://doi.org/10.1002/ejoc.200700834
• (One of the most often downloaded articles in Wiley InterScience).

185. “racemic-Cyclohexane-1,2-diyl Bis(4-nitrobenzoate)” S. T. Tong, D. Barker, K. W. Choi, P. D. W. Boyd and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O2174. https://dx.doi.org/10.1107%2FS1600536808033874

184. “A Comparative Study of the Different Glycosylation Methods for the Synthesis of D-Mannopyranosides of N-alpha-fluorenylmethoxycarbonyl-trans-4-hydroxy-L-proline Allyl Ester” D. J. Lee, R. Kowalczyk, V. J. Muir, P. M. Rendle and M. A. Brimble, Carbohydrate Research, 2007, 342, 2628-2634. https://doi.org/10.1016/j.carres.2007.08.015

183. “Peripheral Administration of a Novel Diketopiperazine, NNZ 2591, Prevents Brain Injury and Improves Somatosensory-Motor Function Following Hypoxia-ischemia in Adult Rats” J. Guan, S. Matai, P. W .R. Harris, M. A. Brimble, J.-Y. Wen, R. Zhang and P. D. Gluckman, Neuropharmacology, 2007, 53, 749-762. https://doi.org/10.1016/j.neuropharm.2007.08.010

182. “Synthesis of Mannosylated Glycopeptides as Components for Synthetic Vaccines” R. Kowalczyk, M. A. Brimble and R. Dunbar, Peptide Science 2007, 88, 539 and in “Advances in Experimental Medicine and Biology,” 2009, 611, 351-352. https://doi.org/10.1007/978-0-387-73657-0_155

181. “Synthesis and Assignment of the Absolute Configuration of the anti-Helicobacter pylori Agents CJ-12,954 and CJ-13,014” M. A. Brimble and C. J. Bryant, Organic and Biomolecular Chemistry, 2007, 5, 2858-2866. https://doi.org/10.1039/b709932k

180. “Synthesis of the FG Fragment of the Pectenotoxins” A. M. Heapy, T. W. Wagner and M. A. Brimble, Synlett, 2007, 2359-2362. http://dx.doi.org/10.1055/s-2007-985600

179. “The Influence of Microwave Irradiation on Lipase-Catalyzed Kinetic Resolution of Racemic Secondary Alcohols” P. Bachu, J. S. Gibson, J. Sperry and M. A. Brimble, Tetrahedron Asymmetry, 2007, 18, 1618-1624. https://doi.org/10.1016/j.tetasy.2007.06.035

178. “Synthesis of the anti-Helicobacter pylori Agent (+)-Spirolaxine Methyl Ether and the Unnatural (2”S)-Diastereomer” J. Robinson and M. A. Brimble, Organic and Biomolecular Chemistry, 2007, 5, 2572-2582. https://doi.org/10.1039/B708265G

177. “Enantioselective Synthesis of an Analogue of Nanaomycin A” M. A. Brimble, P. Bachu and J. Sperry, Synthesis, 2007, 2887-2893. http://dx.doi.org/10.1055/s-2007-983848

176. “A Short Enantioselective Synthesis of the Topoisomerase II Inhibitor (+)-Eleutherin” J. S. Gibson, O. Andrey and M. A. Brimble, Synthesis, 2007, 2611-2613. http://dx.doi.org/10.1055/s-2007-983841

175. “1H and 13C NMR Spectra of Methylmaleimido- and Methylsuccinimidoanthranilate Esters of 1-Hydroxymethyl-6-methoxy-3-azabicyclo[3.3.1]nonanes” K. J. Goodall, M. A. Brimble and D. Barker, Magnetic Resonance in Chemistry, 2007, 45, 695-699. https://doi.org/10.1002/mrc.2027

174. “Assessing the Molecular Basis for Rat-Selective Induction of the Mitochondrial Permeability Transition by Norbormide” A. Zulian, V. Petronilli, S. Bova, F. Dabbeni-Sala, G. Cargnelli, M. Cavalli, D. Rennison, J. Stäb, O. Laita, D. J. Lee, M. A. Brimble, B. Hopkins, P. Bernardi and F. Ricchelli, Biochimica et Biophysica Acta, Bioenergetics, 2007, 1767, 980-988. https://doi.org/10.1016/j.bbabio.2007.04.002

173. “Synthesis of Aromatic Spiroacetals Related to gamma-Rubromycin Based on a 3H-Spiro[1-benzofuran-2,2’-chromane] Skeleton” K. Y. Tsang and M. A. Brimble, Tetrahedron, 2007, 63, 6015-6034. http://dx.doi.org/10.1016/j.tet.2007.02.033
• (Invited Paper for Special 50th Anniversary Issue of Tetrahedron)

172. “Synthesis of Indole Analogues of the anti-Helicobacter pylori Compounds CJ-13,015, CJ-13,102, CJ-13,104 and CJ-13,108” Z. E. Wilson, A. M. Heapy and M. A. Brimble, Tetrahedron, 2007, 63, 5379-5385. https://doi.org/10.1016/j.tet.2007.04.067

171. “A Facile Synthesis of Aryl Spirodioxines Based on a 3H,3’H-2,2’-Spirobi(benzo[b][1,4]dioxane) Skeleton” M. A. Brimble, Y.-C. Liu and M. Trzoss, Synthesis, 2007, 1392-1402. http://dx.doi.org/10.1055/s-2007-966016

170. “Synthesis and Activity Studies of Analogues of the Rat Selective Toxicant Norbormide” D. Rennison, S. Bova, M. Cavalli, F. Ricchelli, A. Zulian, B. Hopkins and M. A. Brimble, Bioorganic and Medicinal Chemistry, 2007, 15, 2963-2974. https://doi.org/10.1016/j.bmc.2007.02.012

169. “Synthesis of Thiacrown and Azacrown Ethers Based on a Spiroacetal Framework” M. A. Brimble, M. Nikac and R. Crumbie, Tetrahedron, 2007, 63, 5220-5226. https://doi.org/10.1016/j.tet.2007.03.174

168. “Synthesis of Isotopically Labelled Thiol Volatiles and Cysteine Conjugates for Quantification of Sauvignon Blanc Wine” K. R. Hebditch, L. Nicolau and M. A. Brimble, Journal of Labelled Compounds and Radiopharmaceuticals, 2007, 50, 237-243. https://doi.org/10.1002/jlcr.1262

167. “Synthesis of a C-Terminal Thioester Derivative of the Lipopeptide Pam2CSKKKKG Using Fmoc SPPS” P. W. R. Harris, M. A. Brimble, R. Dunbar and S. B. H. Kent, Synlett, 2007, 713-716. http://dx.doi.org/10.1055/s-2007-970759

166. “A Facile Synthesis of 1,1’-Spirobi(3H,3’H)isobenzofurans” M. A. Brimble and C. V. Burgess, Synthesis, 2007, 754-760. http://dx.doi.org/10.1055/s-2007-965911

165. “Synthesis of a Regioisomeric Analogue of the 3C-Protease Inhibitor Thysanone via a Hauser Annulation Strategy” M. A. Brimble, S. I. Houghton and P. D. Woodgate, Tetrahedron, 2007, 63, 880-887. https://doi.org/10.1016/j.tet.2006.11.046

164. “Synthesis of the Spiroacetal-Containing anti-Helicobacter pylori Agents CJ-12,954 and CJ-13,014”
M. A. Brimble and C. J. Bryant, Chemical Communications, 2006, 4506-4508. https://doi.org/10.1039/b612757f

163. “Synthesis of New Aza-C-disaccharides Linking 4-Deoxy-4-amino-beta-L-erythro-furanose to C-2 of D-Glucose and D-Allose” E. Rodríguez Garcia, M. A. Brimble and P. Vogel, European Journal of Organic Chemistry, 2006, 3845-3855. https://doi.org/10.1002/ejoc.200600199

162. “1H and 13C NMR Data for C-6 Substituted 3-Azabicyclo[3.3.1]nonane-1-carboxylates” K. Goodall, M. A. Brimble and D. Barker, Magnetic Resonance in Chemistry, 2006, 44, 980-983. https://doi.org/10.1002/mrc.1878

161. “Synthesis of Macrocyclic Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)”
P. W. R. Harris and M. A. Brimble, Organic and Biomolecular Chemistry, 2006, 4, 2696-2709. https://doi.org/10.1039/b605293b

160. “Synthesis of N-(3-Phenylpropyl)-substituted Tricyclic ABE Ring Analogues of the Alkaloid Methyllycaconitine” A. Lehmann, C. Brocke, D. Barker and M. A. Brimble, European Journal of Organic Chemistry, 2006, 3205-3215. http://dx.doi.org/10.1002/ejoc.200600326

159. “Synthesis of the Bis-Spiroacetal Moiety of the Shellfish Toxins Spirolides B and D Using an Iterative Oxidative Radical Cyclization Strategy” K. Meilert and M. A. Brimble, Organic and Biomolecular Chemistry, 2006, 4, 2184-2192. https://doi.org/10.1039/b604334h
• (Hot article and selected for “front cover”).

158. “A Novel Bromine-Induced Ring Expansion of the Spiroimine Moiety of the Shellfish Toxin Gymnodimine” M. A. Brimble, J. E. Robinson, J. Merten, V. Beuzenberg, M. Dragunow, P. Holland and D. Mountfort, Synlett, 2006, 1610-1612. http://dx.doi.org/10.1055/s-2006-941605

157. “Synthesis of Isotopically Labelled Glycyl-L-prolyl-L-glutamic Acid (Glypromate®) and Derivatives” P. W. R. Harris and M. A. Brimble, Journal of Labelled Compounds and Radiopharmaceuticals, 2006, 49, 571-581. https://doi.org/10.1002/jlcr.1075

156. “A Facile Synthesis of Fused Aromatic Spiroacetals Based on the 3,4,3’,4’-Tetrahydro-2,2’-spirobis(2H-1-benzopyran) Skeleton” M. A. Brimble, C. Flowers, M. Trzoss and K. Y. Tsang, Tetrahedron, 2006, 62, 5883-5896. http://dx.doi.org/10.1016/j.tet.2006.04.026

155. “(2”S,5”R,7”S)-2-[2′-(2”-Methyl-1”,6”-dioxaspiro-[4.5]dec-7”-yl)ethylsulfonyl]-1,3-benzothiazole” G. R. Clark, J. E. Robinson and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2006, E62, O1187-O1188. http://dx.doi.org/10.1107/S1600536806006544

154. ”Synthesis of the ABC Tricyclic Fragment of the Pectenotoxins via Stereocontrolled Cyclization of a gamma-Hydroxyepoxide Appended to the AB Spiroacetal Unit” R. Halim, M. A. Brimble and J. Merten, Organic and Biomolecular Chemistry, 2006, 4, 1387-1399. https://doi.org/10.1039/B600951D

153. “8′-Methoxy-3H-spiro[1-naphthofuran-2,2′-chromane]” G. R. Clark, K. Y. Tsang and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2006, E62, O1075-O1076. http://dx.doi.org/10.1107/S1600536806005125

152. “Addition of 2-tert-Butyldimethylsilyloxythiophene to Activated Quinones: An Approach to Thia Analogues of Kalafungin” M. A. Brimble, O. S. Laita and J. E. Robinson, Tetrahedron, 2006, 62, 3021-3027. https://doi.org/10.1016/j.tet.2006.01.040

151. “Synthesis of the Phthalide-Containing anti-Helicobacter pylori agents CJ-13,015, CJ-13,102, CJ-13,103, CJ-13,104 and CJ-13,108” M. A. Brimble, C. L. Flowers, J. K. Hutchinson, J. E. Robinson and M. Sidford, Tetrahedron, 2005, 61, 10036-10047. https://doi.org/10.1016/j.tet.2005.08.027

150. “Synthesis of Proline-Modified Analogues of the Neuroprotective Agent Glycyl-L-prolyl-glutamic Acid (GPE)” P. W. R. Harris, M. A. Brimble, V. J. Muir, M. Y. H. Lai, N. S. Trotter and D. J. Callis, Tetrahedron, 2005, 61, 10018-10035. https://doi.org/10.1016/j.tet.2005.08.026

149. “Synthesis of the Bis-Spiroacetal Moiety of Spirolides B and D” K. Meilert and M. A. Brimble, Organic Letters, 2005, 7, 3497-3500. https://doi.org/10.1021/ol051260u

148. “5,8′-Dimethoxy-3H-1-benzofuran-2-spiro-2′-chroman” G. R. Clark, K. Y. Tsang and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2005, E61, O2748-O2749. https://doi.org/10.1107/S1600536805023731

147. “5-Methoxyspiro[1-benzofuran-2(3H),2′-chroman]” G. R. Clark, K. Y. Tsang and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2005, E61, O1123-O1124. https://doi.org/10.1107/S1600536805008743

146. “6,8′-Dimethoxy-2,2′-spirobichroman” G. R. Clark, C. L. Flowers and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2005, E61, O910-O911. https://doi.org/10.1107/S1600536805006938

145. “Synthesis of the ABC Fragment of the Pectenotoxins” R. Halim, M. A. Brimble and J. Merten, Organic Letters, 2005, 7, 2659-2662. https://doi.org/10.1021/ol0507975

144. “Methyllycaconitine Analogues have Mixed Antagonist Effects at Nicotinic Acetylcholine Receptors”
D. Barker, D. H.-S. Lin, J. E. Carland, C. P.-Y Chu, M. Chebib, M. A. Brimble, G. P. Savage and M. D. McLeod, Bioorganic and Medicinal Chemistry, 2005, 13, 4565-4575. https://doi.org/10.1016/j.bmc.2005.04.054

143. “Use of Bis(aminol) Ethers derived from N-(S)-(–)-alpha-Methylbenzylamine in Reactions With Resorcinarenes and Double Mannich Reactions” B. R. Buckley, P. C. Bulman-Page, H. Heaney, E. P Sampler, S. Carley, C. Brocke and M. A. Brimble, Tetrahedron, 2005, 61, 5876-5888. https://doi.org/10.1016/j.tet.2005.03.130

142. “Investigations into the Cellular Actions of the Shellfish Toxin Gymnodimine and Analogues” M. Dragunow, M. Trzoss, M. A. Brimble, R. Cameron, V. Beuzenberg, P. Holland and D. Mountfort, Environmental Toxicology and Pharmacology, 2005, 20, 305-312. https://doi.org/10.1016/j.etap.2005.02.008

141. “Efficient Synthesis of the Azabicyclo[3.3.1]nonane Ring System in the Alkaloid Methyllycaconitine Using Bis(alkoxymethyl)alkylamines as Aminoalkylating Agents in a Double Mannich Reaction” M. A. Brimble and C. Brocke, European Journal of Organic Chemistry, 2005, 2385-2396. https://doi.org/10.1002/ejoc.200500003

140. “The First Enantioselective Total Synthesis of the anti-Helicobacter pylori Agent (+)-Spirolaxine Methyl Ether” J. Robinson and M. A. Brimble, Chemical Communications, 2005, 1560-1562. https://doi.org/10.1039/B418106A

139. “(1S,2S)-1-{2-[(4-Methoxybenzyl)oxy]ethyl}-2-methyl-3-butenyl (1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylate” K. T. Meilert, G. R. Clark, T. Groutso and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2005, E61, O6-O7. http://dx.doi.org/10.1107/S1600536804030946

138. “Synthesis of Spirolactams via Diels-Alder Addition of 1,3-Butadienes to alpha-Methylenelactams” D. Crimmins, M. Trzoss and M. A. Brimble, Archive for Organic Chemistry (ARKIVOC), 2005, (i), 39-52. http://dx.doi.org/10.3998/ark.5550190.0006.105

137. “Synthesis and Pharmacological Evaluation of Side Chain Modified Glutamic Acid Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)” M. A. Brimble, N. S., Trotter, P. W. R. Harris, M. S. Levi and F. Sieg, Bioorganic and Medicinal Chemistry, 2005, 13, 519-532. https://doi.org/10.1016/j.bmc.2004.10.006

136. “Synthesis and Neuroprotective Activity of Analogues of Glycyl-L-prolyl-L-glutamic Acid (GPE) Modified at the alpha-Carboxylic Acid” N. S. Trotter, M. A. Brimble, P. W. R. Harris, D. J. Callis and F. Sieg, Bioorganic and Medicinal Chemistry, 2005, 13, 501-517. https://doi.org/10.1016/j.bmc.2004.10.005

135. “Synthesis and Pharmacological Evaluation of Glycine-Modified Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)” M. Y. H. Lai, M. A. Brimble, D. J. Callis, P. W. R. Harris, M. S. Levi and F. Sieg, Bioorganic and Medicinal Chemistry, 2005, 13, 533-548. https://doi.org/10.1016/j.bmc.2004.10.004

134. “Synthesis of the 1,6,8-Trioxadispiro[4.1.5.2]tetradec-11-ene Ring System Present in the Spirolide Family of Shellfish Toxins and its Conversion into a 1,6,8-Trioxadispiro[4.1.5.2]-tetradec-9-en-12-ol via Base-Induced Rearrangement of an Epoxide” M. A. Brimble and D. Furkert, Organic and Biomolecular Chemistry, 2004, 2, 3573-3583. https://doi.org/10.1039/b412883d

133. “Application of a Double Mannich Reaction Using Bis(aminol) Ethers in the Synthesis of AE Ring Analogues of Methyllycaconitine” C. Brocke, M. A. Brimble, D. S. H. Lin and M. D. McLeod, Synlett, 2004, 2359-2363. http://dx.doi.org/10.1055/s-2004-831340

132. “Synthesis of Simple Analogues of Methyllycaconitine – An Efficient Method for the Preparation of the N-Substituted Anthranilate Pharmacophore” D. Barker, M. A. Brimble and M. D. McLeod, Tetrahedron, 2004, 60, 5953-5963. https://doi.org/10.1016/j.tet.2004.05.024

131. “Synthesis of Pyrrolo[3,2-b]benzofurans and Pyrrolo[3,2-b]naphthofurans via Addition of a Silyloxypyrrole to Activated Quinones” M. A. Brimble, C. Burgess, R. Halim, M. Petersson and J. Ray, Tetrahedron, 2004, 60, 5751-5758. https://doi.org/10.1016/j.tet.2004.05.008

130. “Synthesis of a Novel Nucleoside Based on a Spiroacetal Framework” M. A. Brimble, J. E. Robinson, K. W. Choi and P. D. Woodgate, Australian Journal of Chemistry, 2004, 57, 665-668. http://dx.doi.org/10.1071/CH04021

129. “Synthesis of Tricyclic Analogues of Methyllycaconitine Using Ring Closing Metathesis to Append a B Ring to an AE Azabicyclic Fragment” D. Barker, M. A. Brimble, M. D. McLeod and G. P. Savage, Organic and Biomolecular Chemistry, 2004, 2, 1659-1669. http://dx.doi.org/10.1039/b401119h

128. “A Double Alkylation – Ring Closing Metathesis Approach to Spiroimines” M. A. Brimble and M. Trzoss, Tetrahedron, 2004, 60, 5613-5622. https://doi.org/10.1016/j.tet.2004.04.059

127. “Two Stereoisomers of the Rat Toxicant Norbormide” P. J. Steel, M. A. Brimble, B. Hopkins and D. Rennison, Acta Crystallographica, Section C: Crystal Structure Communications, 2004, 60, O374-O376. https://doi.org/10.1107/s0108270104006845

126. “Synthesis and Evaluation of Vasoconstrictor and Vasorelaxant Activity of Norbormide Isomers” M. A. Brimble, V. J. Muir, B. Hopkins and S. Bova, Archive for Organic Chemistry (ARKIVOC), 2004, (i), 1-11.

125. “Radical Oxidative Cyclization of Spiroacetals to Bis-Spiroacetals: An Overview” M. A. Brimble, Molecules, 2004, 9, 394-404. http://dx.doi.org/10.3998/ark.5550190.0005.101

124. “Use of a Sonogashira-Acetylide Coupling Strategy for the Synthesis of the Aromatic Spiroketal Skeleton of gamma-Rubromycin” M. A. Brimble, K. Y. Tsang and J. B. Bremner, Organic Letters, 2003, 5, 4425-4427. https://doi.org/10.1021/ol035723c

123. “Synthesis of Regioisomeric Analogues of Crisamicin A” M. A. Brimble and M. Y. H. Lai, Organic and Biomolecular Chemistry, 2003, 1, 4227-4234. https://doi.org/10.1039/B309722F

122. “Synthesis of Spirocyclic Imines: Key Pharmacophores in the Shellfish Toxins Spirolides and Gymnodimine” M. A. Brimble and M. Trzoss, Synlett, 2003, 2042-2046. http://dx.doi.org/10.1055/s-2003-41481

121. “Synthesis of the Spiroacetal Fragment of Broussonetine H” M. A. Brimble, J. H. Park and C. M. Taylor,
Tetrahedron, 2003, 59, 5861-5868. https://doi.org/10.1016/S0040-4020(03)00949-9

120. “Synthesis of Cyclic Proline-Containing Peptides via Ring–Closing Metathesis” M. A. Brimble, P. W. R. Harris and P. D. Gluckman, Organic Letters, 2003, 5, 1847-1850. https://doi.org/10.1021/ol034370e

119. “Suzuki-Miyaura Homocoupling of Naphthyl Triflates Using Bis(pinacolato)diboron: Approaches to the Biaryl Skeleton of Crisamicin A” M. A. Brimble and M. Y. H. Lai, Organic and Biomolecular Chemistry, 2003, 1, 2084-2095. https://doi.org/10.1039/B303070A

118. “Synthesis of 3-Azido-2,3,6-trideoxy-beta-D-arabino-hexopyranosyl Pyranonaphthoquinone Analogues of Medermycin” M. A. Brimble, R. M. Davey, M. D. McLeod and M. Murphy, Organic and Biomolecular Chemistry, 2003, 1, 1690-1700. https://doi.org/10.1039/B301449P

117. “C-Glycosylation of Oxygenated Naphthols with 3-Dimethylamino-2,3,6-trideoxy-L-arabino-hexopyranose and 3-Azido-2,3,6-trideoxy-D-arabino-hexopyranose” M. A. Brimble, R. M. Davey, M. D. McLeod and M. Murphy, Australian Journal of Chemistry, 2003, 56, 787-794. http://dx.doi.org/10.1071/CH02236

116. “Addition of 2-[(Trimethylsilyloxy)]furan to 2-Acetyl-1,4-benzoquinone Using Chiral Non-Racemic Copper(II)-pybox Catalysts” M. A. Brimble, M. D. K. N. Towers and P. D. Woodgate, Archive for Organic Chemistry (ARKIVOC), 2003, (i), 43-55. http://dx.doi.org/10.3998/ark.5550190.0004.106

115. “Addition of Silyloxydienes to 2,6-Dibromo-1,4-benzoquinone: an Approach to Highly Oxygenated Bromonaphthoquinones for the Synthesis of Thysanone” D. Barker, M. A. Brimble, P. Do and P. Turner, Tetrahedron, 2003, 59, 2441-2449. https://doi.org/10.1016/S0040-4020(03)00291-6

114. “A Convenient Synthesis of 2-(3-Methyl-2,5-dioxopyrrolidin-1-yl)benzoic Acid” D. Barker, M. A. Brimble and M. D. McLeod, Synthesis, 2003, 656-658. https://doi.org/10.1055/s-2003-38065

113. “Synthesis of the C10-C22 Bis-Spiroacetal Domain of Spirolides B and D via Iterative Radical Cyclisation” M. A. Brimble and D. P. Furkert, Organic Letters, 2002, 4, 3655-3658. https://doi.org/10.1021/ol026605c

112. “cis-2-(2-Methoxyphenyl)-3-(phenylselenyl)tetrahydropyran” C. E. F. Rickard, M. A. Brimble, G. S. Pavia and R. J. Stevenson, Acta Crystallographica, Section E: Structure Reports Online, 2002, E58, O933-O934. https://doi.org/10.1107/S1600536802013272

111. “trans-2-(2-Naphthyl)-3-(phenylselenyl)tetrahydropyran” C. Rickard, M. A. Brimble, G. S. Pavia and R. J. Stevenson, Acta Crystallographica, Section E: Structure Reports Online, 2002, E58, O931-O932. http://dx.doi.org/10.1107/S1600536802013260

110. “Application of Olefin Metathesis to the Synthesis of ABE Ring Analogues of Methyllycaconitine” D. Barker, M. D. McLeod, M. A. Brimble and G. P. Savage, Tetrahedron Letters, 2002, 43, 6019-6022. https://doi.org/10.1016/S0040-4039(02)01214-5

109. “Addition of a Chiral Non-racemic Silyloxypyrrole to an Activated 1,4-Benzoquinone” R. Halim, M. A. Brimble and P. D. Woodgate, Archive for Organic Chemistry (ARKIVOC), 2002, (i), 61-70. http://dx.doi.org/10.3998/ark.5550190.0003.110

108. “Synthesis of Azido Analogue of Medermycin” M. A. Brimble, R. M. Davey and M. D. McLeod, Synlett, 2002, 1318-1322. http://dx.doi.org/10.1055/s-2002-32955

107. “Uncatalyzed Addition of N-(tert-Butoxycarbonyl)-2-tert-butyldimethylsilyloxypyrrole to Activated Quinones” M. A. Brimble, R. Halim and M. Petersson, Tetrahedron Letters, 2002, 43, 4777-4780. https://doi.org/10.1016/S0040-4039(02)00932-2

106. “Synthesis of ABE Tricyclic Analogues of Methyllycaconitine Using a Wacker Oxidation – Aldol Strategy to append the B Ring to the AE Fragment“ D. Barker, M. A. Brimble, M. McLeod, G. P. Savage and D. Wong, Journal of the Chemical Society, Perkin Transactions 1, 2002, 924-931. https://doi.org/10.1039/B200073N

105. “A Facile Synthesis of Aryldihydropyrans Using a Sonogashira-Selenoetherification Strategy” M. A. Brimble, G. S. Pavia and R. J. Stevenson, Tetrahedron Letters, 2002, 43, 1735-1738. http://dx.doi.org/10.1016/S0040-4039(02)00065-5

104. “Stereoselective Synthesis of Deoxy Analogues of the 3C Protease Inhibitor Thysanone” M. A. Brimble and R. J. R. Elliott, Tetrahedron, 2002, 58, 183-189. https://doi.org/10.1016/S0040-4020(01)01120-6

103. “Synthesis of a Spiroacetal Intermediate for the Synthesis of the anti-Helicobacter pylori agent CJ-12,954” M. A. Brimble, C. J. Funnell, S. Gorsuch and M. D. Sidford, Archive for Organic Chemistry (ARKIVOC), 2001, (i), 74-87. https://doi.org/10.3998/ark.5550190.0002.106

102. “Determining the Regio- and Typo-Selectivity of Calf Pregastric Lipase” C. J. O’Connor, K. Bang, C. M. Taylor and M. A. Brimble, Journal of Molecular Catalysis B: Enzymatic, 2001, 147-157. https://doi.org/10.1016/S1381-1177(01)00052-2

101. “C-Glycosylation of Naphthols Using Glucosyl Donors” M. A. Brimble and T. J. Brenstrum, Archive for Organic Chemistry (ARKIVOC), 2001, (vii), 37-48. http://dx.doi.org/10.3998/ark.5550190.0002.704

100. “Synthesis of a 2-Deoxyglucosyl Analogue of Medermycin” M. A. Brimble and T. J. Brenstrum, Journal of the Chemical Society, Perkin Transactions 1, 2001, 1624-1634.

99. “C-Glycosylation of Tri-O-benzyl-2-deoxy-D-glucose: Synthesis of Naphthyl Substituted 3,6-Dioxabicyclo[3.2.2]nonanes” M. A. Brimble and T. J. Brenstrum, Journal of the Chemical Society, Perkin Transactions 1, 2001, 1612-1623.

98. “Synthesis of the Novel 1,7,9-Trioxa[4.1.5.2]-tetradecane Ring System Present in the Spirolides” M. A. Brimble, V. Caprio and D. P. Furkert, Tetrahedron, 2001, 57, 4023-4034.

97. “Synthesis of Arylspiroketals Related to the Papulacandins via Generation of Phthalide Oxycarbenium Ions” M. A. Brimble, V. Caprio, A. D. Johnston and M. D. Sidford, Synthesis, 2001, 855-862.

96. “A High Yielding Synthesis of Anthranilate Esters from Sterically Hindered Alcohols” D. Barker, M. A. Brimble, M. D. McLeod and G. P. Savage, Tetrahedron Letters, 2001, 42, 1785-1788.

95. “Synthesis of the Bis-Spiroacetal Moiety of the Polyether Antibiotic CP44,161” M. A. Brimble, P. R. Allen and H. Prabaharan, Journal of the Chemical Society, Perkin Transactions 1, 2001, 379-389.

94. “endo-(1’R,2’R,5’S,7’S,9’S)-2-(9’-Benzyloxy-2’-phenyl-3’,6’-dioxabicyclo[3.3.2]nonan-7’-yl)-7-bromo-5,8-dimethoxynaphthalen-1-yl acetate” T. J. Brenstrum, M. A. Brimble and P. Turner, Acta Crystallographica, Section E: Structure Reports Online, 2001, E57, O28-O29.

93. “Polyether Antibiotic CP44,161” P. Allen, M. A. Brimble and P. Turner, Acta Crystallographica, Section C: Crystal Structure Communications, 2001, 57, 95-96.

92. “Synthesis of an Oxaspirolactone Intermediate for the Synthesis of Spirolides” M. A. Brimble, F. A. Fares and P. Turner, Australian Journal of Chemistry, 2000, 53, 845-851.

91. “Enantioselective Synthesis of a Cyclopentannulated Kalafungin Analogue” M. A. Brimble and J. F. McEwan, Archive for Organic Chemistry (ARKIVOC), 2000, (i), 909-916.

90. “Diels-Alder Addition of Acyclic Dienes to Chiral Naphthoquinones” M. A. Brimble, R. J. Elliott and J. F. McEwan, Australian Journal of Chemistry, 2000, 53, 571-576.

89. “Regioselective Asymmetric Aminohydroxylation of Precursors to 2,3,6-Trideoxy-3-aminohexoses” M. A. Brimble, R. M. Davey and M. D. McLeod, Tetrahedron Letters, 2000, 41, 5141-5146.

88. “Synthesis of Aryl Spiroketals Related to the Papulacandins via Allylation of Phthalides” M. A. Brimble, V. E. Caprio, A. D. Johnston and M. H. Sidford, Tetrahedron Letters, 2000, 41, 3955-3958.

87. “Diels-Alder Cycloaddition of Cyclopentadiene to a Bis-Naphthoquinone” M. A. Brimble and L. J. Duncalf, Molecules, 2000, 5, 162-166.

86. “Synthesis of a C-Glycosylpyranonaphthoquinone Related to Medermycin” M. A. Brimble and T. J. Brenstrum, Tetrahedron Letters, 2000, 41, 2991-2994.

85. “A Titanium Naphtholate Approach for the Synthesis of Analogues of Griseusin A” M. A. Brimble, M. R. Nairn and J. S. O. Park, Journal of the Chemical Society, Perkin Transactions 1, 2000, 697-709.

84. “Synthesis of Naphthyl C-Glycosides of Rearranged Tri-O-benzyl-2-deoxy-D-glucose” M. A. Brimble and T. J. Brenstrum, Tetrahedron Letters, 2000, 41, 1107-1110.

83. “Reductive Thioalkylation of a Pyranonaphthoquinone” M. A. Brimble and M. R. Nairn, Journal of the Chemical Society, Perkin Transactions 1, 2000, 317-322.

82. “Reaction of Bromonaphthofurans with Bis(pinacolato)diboron” M. A. Brimble and F. Issa, Australian Journal of Chemistry, 1999, 52, 1021-1028.

81. “Deprotonation and Alkylation of 2-Methyl-4,5,6,7-tetrahydrofuro-3H-azepine” M. A. Brimble and S. Gorsuch, Australian Journal of Chemistry, 1999, 52, 965-969.

80. “Synthesis of Analogues of Griseusin A” M. A. Brimble, M. R. Nairn and J. Park, Organic Letters, 1999, 1, 1459-1462.

79. “Addition of a Grignard Reagent to Bis-Spiroacetal Aldehydes: Appendage of a Tetrahydrofuran Ring” M. A. Brimble and H. Prabaharan, Journal of the Chemical Society, Perkin Transactions 1, 1999, 2795-2802.

78. “Reactions of Semiquinones in Aqueous Solution. A Comparison of One Electron Reduction of Kalafungin and Analogues With Other Semiquinones Using Pulse Radiolysis” R. F. Anderson, M. A. Brimble, M. R. Nairn and J. E. Packer, Journal of the Chemical Society, Perkin Transactions 2, 1999, 475-479.

77. “Synthetic Studies towards the B,C,D,E Fragment of Antibiotic CP44,161” P. A. Allen, M. A. Brimble, and H. Prabaharan, Synlett, 1999, 295-298.

76. “The Synthesis of Oxygenated Naphthyl Stannanes Possessing ortho-Methoxy Substituents for use in Stille Coupling Reactions” M. A. Brimble and L. J. Duncalf, Australian Journal of Chemistry, 1999, 52, 19-29.

75. “Double Furofuran Annulation to a Bis-Naphthoquinone: An Approach to Dimeric Pyranonaphthoquinones” M. A. Brimble, L. J. Duncalf and D. Neville, Journal of the Chemical Society, Perkin Transactions 1, 1998, 4165-4173.

74. “Synthesis of a Novel Cage Compound via Oxidative Rearrangement of a Dihydronaphthofuran” M. A. Brimble, R. J. R. Elliott and P. Turner, Tetrahedron, 1998, 54, 14053-14058.

73. “Synthesis of Chiral Diazanedicarboxylates” M. A. Brimble, M. J. Duckworth and C. Y. K. Lee, Australian Journal of Chemistry, 1998, 51, 907-913.

72. “Synthesis of a Dimeric Pyranonaphthoquinone via a Novel Double Furofuran Annulation Strategy” M. A. Brimble, D. Neville and L. J. Duncalf, Tetrahedron Letters, 1998, 39, 5647-5650.

71. “Reductive Thioalkylation of a Kalafungin Analogue” M. A. Brimble and M. R. Nairn, Tetrahedron Letters, 1998, 39, 4879-4882.

70. “Synthesis of C-2 Functionalised 1,6,8-Trioxadispiro[4.1.5.3]pentadec-13-enes” M. A. Brimble, P. R. Allen and F. Fares, Journal of the Chemical Society, Perkin Transactions 1, 1998, 2403-2411.

69. “Addition of Cyclopentadiene and 2-Trimethylsilyloxyfuran to Quinones Bearing a Menthyl Ester Chiral Auxiliary” M. A. Brimble, L. J. Duncalf, D. C. W. Reid and T. R. Roberts, Tetrahedron, 1998, 54, 5363-5374.

68. “Asymmetric Michael Addition of 2-Trimethylsilyloxyfuran to Chiral Naphthoquinones” M. A. Brimble, J. F. McEwan and P. Turner, Tetrahedron Asymmetry, 1998, 9, 1257-1267.

67. “Asymmetric Diels-Alder Addition of Cyclopentadiene to Chiral Naphthoquinones” M. A . Brimble, J. F. McEwan and P. Turner, Tetrahedron Asymmetry, 1998, 9, 1239-1255.

66. “Synthesis of 7-Methoxy-3’,4’,5’,6’-tetrahydrospiro[isobenzofuran-1(3H),2’-pyran]-3-one and 5,7-Dimethoxy-3’,4’,5’,6’-tetrahydrospiro[isobenzofuran-1(3H),2’-pyran]-3-one” M. A. Brimble and S. Chan, Australian Journal of Chemistry, 1998, 51, 235-242.

65. “Asymmetric Azo-ene Reactions Using the Chiral Azo-Enophile Di-(–)-(1R,2S)-2-phenyl-1-cyclohexyl Diazenedicarboxylate” M. A. Brimble and C. Y .K. Lee, Tetrahedron Asymmetry, 1998, 9, 873-884.

64. “Approaches to the D-E Ring of the Polyether Antibiotic Salinomycin Using Sharpless Asymmetric Dihydroxylation” M. A. Brimble and H. Prabaharan, Tetrahedron, 1998, 54, 2113-2128.

63. “Addition of Allylsilanes to an Oxy-Stabilized Carbenium Ion on a 1,7-Dioxaspiro [5.5]-undecane Ring System” M. A. Brimble, F. Fares and P. Turner, Journal of the Chemical Society, Perkin Transactions 1, 1998, 677-684.

62. “Synthesis of Crown Ethers Based on a Spiroacetal Framework” M. A. Brimble and A. D. Johnston, Journal of the Chemical Society, Perkin Transactions 1, 1998, 265-270.

61. “Synthesis and Herbicidal Activity of [3R*,5S*,6S*]-3-Benzyloxy-5-methoxy-1,7-dioxaspiro[5.5]undecane and [3R*,5S*,6S*]-3-Methoxy-5-benzyloxy-1,7-dioxaspiro-[5.5]undecane” M. A. Brimble, R. J. Furneaux and A. D. Johnston, Journal of Organic Chemistry, 1998, 63, 471-479.

60. “Use of Bis(oxazoline)-Metal Complexes as Chiral Catalysts for Asymmetric Diels-Alder Reactions Using 2-Acetyl-1,4-naphthoquinone as Dienophile” M. A. Brimble and J. F. McEwan, Tetrahedron Asymmetry, 1997, 8, 4069-4078.

59. “Synthesis of 8-Bromokalafungin as an Intermediate for the Preparation of C-Glycoside Derivatives”
M. A. Brimble, M. R. Nairn, H. Prabaharan and N. B. Walters, Australian Journal of Chemistry, 1997, 50, 711-718.

58. “Addition of Silyloxydienes to 2-Substituted 1,4-Benzoquinones and 1,4-Naphthoquinones” M. A. Brimble and R. J. Elliott, Tetrahedron, 1997, 53, 7715-7730.

57. “Kinetic Resolution in the Asymmetric Dihydroxylation of 1,7-Dioxaspiro[5.5]-undec-4-enes” M. A. Brimble and A. D. Johnston, Tetrahedron Asymmetry, 1997, 8, 1661-1676.

56. “Synthesis of a New Spiroacetal Based Herbicide” M. A. Brimble, R. J. Furneaux and A. D. Johnston, Tetrahedron Letters, 1997, 38, 3591-3594.

55. “Synthesis of the Monomeric Unit of gamma-Actinorhodin” M. A. Brimble, L. J. Duncalf and S. J. Phythian, Journal of the Chemical Society, Perkin Transactions 1, 1997, 1399-1403.

54. “Facile Bisarylation of Aldehydes using Titanium Naphtholates” M. A. Brimble and E. Oppen, Synthetic Communications, 1997, 27, 989-1007.

53. “Crystal Structures of (3S*,4S*,5S*,6S*)-3,4-Epoxy-1,7-dioxaspiro[5.5]undecan-5-ol, (3R*,5S*,6S*)-1,7-Dioxaspiro[5.5]undec-3,5-diyl Diacetate and (4S*,5S*,6S*)-1,7-Dioxaspiro[5.5]undecan-4,5-diol” M. A. Brimble, A. D. Johnston, T. W. Hambley and P. Turner, Australian Journal of Chemistry, 1997, 50, 123-127.

52. “Synthesis and Ene Reactions of Di-(–)-menthyl Diazenedicarboxylate” M. A. Brimble, C. H. Heathcock and G. N. Nobin, Tetrahedron Asymmetry, 1996, 7, 2007-2016.

51. “Synthesis of Tricyclic Aryl Spiroacetals Related to the Papulacandins” M. A. Brimble and S. G. Robinson,
Tetrahedron, 1996, 52, 9553-9565.

50. “Synthesis of Spiroketals Related to Griseusin A” M. A. Brimble and M. R. Nairn, Molecules, 1996, 1, 3-14.

49. “Woodward-Prevost Reactions of 1,7-Dioxaspiro[5.5]undec-4-enes” M. A. Brimble and M. R. Nairn, Journal of Organic Chemistry, 1996, 61, 4801-4805.

48. “Synthesis of Aromatic Spiroacetals” M. A. Brimble, G. M. Horner and R. J. Stevenson, Australian Journal of Chemistry, 1996, 49, 189-196.

47. “Synthesis of Chiral Hydroxylated Farnesene Derivatives” M. A. Brimble, J. A. Spicer and D. D. Rowan, Synthesis, 1996, 116-122.

46. “Synthesis of (E)-1-Bromo-3-ethyl-3-pentene” M. A. Brimble and M. K. Edmonds, Synthetic Communications, 1996, 26, 243-251.

45. “Synthesis of an Actinorhodin Monomer” M. A. Brimble, L. J. Duncalf and S. J. Phythian, Tetrahedron Letters, 1995, 36, 9202-9210.

44. “Synthesis of Arizonin C1” M. A. Brimble, S. J. Phythian and H. Prabaharan, Journal of the Chemical Society, Perkin Transactions 1, 1995, 2855-2860.

43. “Enantioselective Synthesis of the Apple Aroma Constituent 1,3,3-Trimethyl-2,7-dioxabicyclo[2.2.1]heptane via Asymmetric Dihydroxylation” M. A. Brimble, D. D. Rowan and J. A. Spicer, Synthesis, 1995, 1263-1266.

42. “Synthesis of Bis-2,5-linked Tetrahydrofurans via Iodoetherification” M. A. Brimble and M. K. Edmonds,
Tetrahedron, 1995, 51, 9995-10012.

41. “Identification of Conjugated Triene Oxidation Products of alpha-Farnesene in Appleskin” J. M. Allen, M. A. Brimble, S. Fielder, D. D. Rowan, and J. A. Spicer, Journal of Agriculture and Food Chemistry, 1995, 43, 2040-2045.

40. “Diastereoselective Addition of 2-Trimethylsilyloxyfuran to (S)-(+)-2-(p-Tolylsulfinyl)-1,4-benzoquinone” M. A. Brimble, L. J. Duncalf and D. C. W. Reid, Tetrahedron Asymmetry, 1995, 6, 263-269.

39. “Asymmetric Dihydroxylation of alpha- and beta-Farnesene” M. A. Brimble, D. D. Rowan and J. A. Spicer, Tetrahedron Letters, 1994, 35, 9445-9446.

38. “Formal Synthesis of the Juglomycins” M. A. Brimble and E. Ireland, Journal of the Chemical Society, Perkin Transactions 1, 1994, 3109-3104.

37. “Synthesis of Conjugated Trienes and Related Oxidation Products of alpha-Farnesene” M. A. Brimble, D. D. Rowan and J. A. Spicer, Australian Journal of Chemistry, 1994, 47, 1979-1988.

36. “Directed ortho Metallations of Tertiary Benzamides using Lactones as Electrophiles” T. J. Brenstrum, M. A. Brimble and R. J. Stevenson, Tetrahedron, 1994, 50, 4897-4904.

35. “Synthesis of Bicyclic Pyrazinones via Addition of Heterocyclic Amines to a Nitro-alkene” M. A. Brimble and A. D. Johnston, Tetrahedron, 1994, 50, 4887-4896.

34. “Synthesis of trans- and cis-14-Phenylsulfonyl-1,7,9-trioxadispiro[5.1.5.3]hexadecane” M. A. Brimble and C. J. Rush, Journal of the Chemical Society, Perkin Transactions 1, 1994, 497-500.

33. “A Short Synthesis of Deoxyfrenolicin” M. A. Brimble and S. M. Lynds, Journal of the Chemical Society, Perkin Transactions 1, 1994, 493-496.

32. “Oxidation of alpha-Farnesene” M. A. Brimble, D. D. Rowan and J. A. Spicer, Australian Journal of Chemistry, 1993, 46, 1929-1939.

31. “Synthesis of 5-epi-Arizonin B1 and 5-epi-Arizonin C1” M. A. Brimble and S. J. Phythian, Tetrahedron Letters, 1993, 34, 5813-5814.

30. “Allylic Amination by the Lewis-Acid-Mediated Ene Reaction of Diethyl Azodicarboxylate with Alkenes” M. A. Brimble and C. H. Heathcock, Journal of Organic Chemistry, 1993, 58, 5261-5263.

29. “Structure of a Bis-Spiroacetal, cis-14-Phenylsulphonyl-1,7,9-trioxadispiro[5.1.5.3]hexadecane” E. N. Baker, M. A. Brimble, G. E. Norris, and C. J. Rush, Crystallographica, Section C: Crystal Structure Communications, 1993, 49, 1857-1859.

28. “Dihydroxylation of 1,7-Dioxaspiro[5.5]undec-4-enes” M. A. Brimble and M. R. Nairn, Australian Journal of Chemistry, 1993, 46, 195-201.

27. “Synthesis of the Bis-Spiroacetal Moiety of 17-epi-20-Deoxysalinomycin” M. A. Brimble and G. M. Williams, Journal of Organic Chemistry, 1992, 57, 5818-5822.

26. “Allylic Functionalization of the 1,7-Dioxaspiro[5.5]undec-4-ene and 1,6,8-Trioxadispiro[4.1.5.3]pentadec-13-ene Ring Systems” M. A. Brimble, M. K. Edmonds, and G. M. Williams, Tetrahedron, 1992, 48, 6455-6466.

25. “Synthesis of Deuterated Hexenols” T. J. Brenstrum, M. A. Brimble, C. J. Rush, J. G. Shaw and D. C. W. Reid, Journal of Labelled Compounds and Radiopharmaceuticals, 1992, 8, 629-635.

24. “Synthesis of a Pyranonaphthoquinone-Spiroacetal” M. A. Brimble and M. R. Nairn, Journal of the Chemical Society, Perkin Transactions 1, 1992, 579-583.

23. “Synthesis of 5′-Deoxyjuglomycin A and 5′-Methoxyjuglomycin A” M. A. Brimble, E. Ireland and S. J. Phythian, Tetrahedron Letters, 1991, 32, 6417-6420.

22. “Chemistry of Bis-Spiroacetals: Synthesis of cis- and trans-1-(2-Methyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-2-yl)methanol” M. A. Brimble, G. M. Williams and R. Baker, Journal of the Chemical Society, Perkin Transactions 1, 1991, 2221-2227.

21. “Highly Stereoselective syn-Hydroxylation of Spiroketals” M. A. Brimble, M. R. Nairn and Y. Wu, Tetrahedron Letter, 1991, 32, 4049-4050.

20. “Approaches to a Key Lactone Intermediate Required for the Synthesis of Pyranonaphthoquinone Antibiotics” M. A. Brimble and J. A. Spicer, Australian Journal of Chemistry, 1991, 44, 197-205.

19. “Allylic Oxidation of Unsaturated Spiroketals” M. A. Brimble, M. K. Edmonds and G. M. Williams, Tetrahedron Letters, 1990, 31, 7509-7512.

18. “Synthesis of a Functionalised Bis-Spiroacetal” M. A. Brimble, G. M. Williams, R. Baker and M. James, Tetrahedron Letters, 1990, 31, 3043-3046.

17. “Stereocontrolled Synthesis of a Key Lactone Intermediate Required for the Synthesis of Salinomycin” M. A. Brimble, Australian Journal of Chemistry, 1990, 43, 1035-1046.

16. “The Chemistry of Bis-Spiroacetals. Synthesis of the Novel 1,7,9-Trioxadispiro-[5.1.5.3]hexadecane Ring System” M. A. Brimble, C. J. Rush, G. M. Williams and E. N. Baker, Journal of the Chemical Society, Perkin Transactions 1, 1990, 414-416.

15. “Effect of the Fungal Metabolite Peramine and Analogues on Feeding and Development of the Argentine Stem Weevil (Listronotus bonariensis)” M. A. Brimble, D. D. Rowan and J. J. Dymock, Journal of Chemical Ecology, 1990, 16, 1683-1695.

14. “Synthesis of 5-epi-7-Deoxykalafungin and 5-epi-7-O-Methylkalafungin” M. A Brimble and S. J. Stuart, Journal of the Chemical Society, Perkin Transactions 1, 1990, 881-885.

13. “Synthesis of the Griseusin A Ring System” M. A. Brimble and M. R. Nairn, Journal of the Chemical Society, Perkin Transactions 1, 1990, 169-171.

12. “Synthesis of the Insect Feeding Deterrent Peramine via Michael Addition of a Pyrrole Anion to a Nitroalkene” M. A. Brimble and D. D. Rowan, Journal of the Chemical Society, Perkin Transactions 1, 1990, 311-314.

11. “Synthesis of the cis-3a,8b-Dihydrofuro[3,2-b]benzofuran-2(3H)-one Ring System via a Furofuran Annulation to Activated Benzoquinones” M. A. Brimble, M. T. Brimble and J. J. Gibson, Journal of the Chemical Society, Perkin Transactions 1, 1989, 179-184.

10. “Rearrangement of a Furo[3,2-b]naphtho[2,1-d]furan to a Pyranonaphthoquinone” M. A. Brimble, R. Hodges and S. J. Stuart, Tetrahedron Letters, 1988, 29, 5987-5990.

9. “Synthesis of Peramine: An Insect Feeding Deterrent Mycotoxin from Acremonium Lolii” M. A. Brimble and D. D. Rowan, Journal of the Chemical Society, Chemical Communications, 1988, 978-979.

8. “Synthesis of 2-Methylpyrrolo[1,2-a]pyrazin-1(2H)-one” M. A. Brimble, M. T. Brimble, R. Hodges and G. A. Lane, Australian Journal of Chemistry, 1988, 41, 1583-1590.

7. “A Facile Synthesis of Spiroketals” M. A. Brimble, D. L. Officer and G. M. Williams, Tetrahedron Letters, 1988, 29, 3609-3612.

6. “The Chemistry of Bis-Spiroacetals. Synthesis of the 1,6,8-Trioxadispiro[4.1.5.3]pentadecane Ring System” R. Baker and M. A. Brimble, Journal of the Chemical Society, Perkin Transactions 1, 1988, 125-131.

5. “1,4-Addition of 2-Trimethylsilyloxyfuran to Quinones: A Facile Route to the Furo[3,2-b]benzofuran Nucleus” M. A. Brimble, M. T. Brimble, J. J. Gibson, R. Baker, A. A. Kee and M. J. O’Mahony, Tetrahedron Letters, 1987, 28, 4891-4892.

4. “Synthesis of Two Key Intermediates Required for the Construction of the Bis-Spiroacetal Moiety of epi-17-Deoxy-(O-8)-salinomycin” R. Baker and M. A. Brimble, Tetrahedron Letters, 1986, 27, 3311-3314.

3. “Determination of the Stereochemistry of 2,2-Dimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-ene Formed by Two Sequential Cyclization Reactions Using High Field 1H NMR Spectroscopy” R. Baker, M. A. Brimble, and J. A. Robinson, Tetrahedron Letters, 1985, 26, 2115-2118.

2. “The Chemistry of Spiroacetals. Approaches to the Novel 1,6,8-trioxadispiro[4.1.5.3]pentadecane Ring System” R. Baker and M. A. Brimble, Journal of the Chemical Society, Chemical Communications, 1985, 78-80.

1. “Diastereoselective Diels-Alder Reactions of Optically-Active Vinyl Sulphoxides” M. A. Brimble and B. R. Davis, Tetrahedron, 1985, 41, 4965-4971.

Non-Refereed Journals

30. “Preliminary Field Trials with a Palatable Form of Norbormide” L. Shapiro, C. Eason, D. MacMorran, D. Rennison, M. A. Brimble and M. Jackson, Proceedings of the 29th Vertebrate Pest Conference, D. M. Woods Ed., 2020, paper 55, 1-3.

29. “The Post-lockdown Period Should be Used to Acquire Effective Therapies for Future Resurgence in SARS-Cov-2 Infections,” K. L. Krause, R. Furneaux, P.Benjes, M. A. Brimble, T. Davidson, B. Denny, L. Harris, S. Hinkley, P. Tyler, J. Ussher and Vernon Ward, New Zealand Medical Journal, 24 April 2020, vol. 133, No. 1513, p107-111.

28. “Redevelopment of a Rat Specific Rodenticide Norbormide” L. Shapiro, D. Rennison, M. A. Brimble, D. MacMorran and C. Eason, Proceedings of the 28th Vertebrate Pest Conference, D. M. Woods Ed., 2018, 47-50.

27. “Global Trends in the Development of Rodenticides and Mammalian Pest Control Technologies” C. Eason, W. Linklater, M. Jackson, L. Shapiro, H. Blackie, C.Morley, S. Olgivie, D. Rennison and M. A. Brimble, Proceedings of the 28th Vertebrate Pest Conference, D. M. Woods Ed., 2018, 3-10.

26. “Organic Synthesis: Where to From Now? A Personal Perspective From Down Under,” M. A. Brimble, Organic Letters, 2019, 21, 5773-5774.

25. “Characterising the Mode of Action of Connexin43 Mimetic Peptide5 to Target Retinal Ischemia-Reperfusion Injury,” Y. Kim, J. M. Griffin, P. W. R. Harris, S. H. C. Chan, L.F. B. Nicholson, S. J. O’Carroll, M. A. Brimble and C. Green, Investigative Ophthalmology & Visual Science, 2016, 57, 4592-4592.

24. “Weight Loss After Pregnancy is Associated with Reduced IGFBP-3 and Increased cGP/IGF-1 Ratio” J. Guan, K. Liu, G. S. Mallah, L. McGowan, P. Shorten, J. Thompson, E. Mitchell, R. Taylor, P. Harris, M. A. Brimble and R. Murphy, Endocrine Abstracts, 2016, 41 EP709B | DOI:10.1530/endoabs.41.EP709B

23. “Strategies for Inhibiting Advanced Glycation Endproduct (Age) Induced Vascular Calcification in a Smooth Muscle Cell Culture Mode” G. P. Sidgwick, P. Walling, A. Shabbir, R. Weston, A. Schiro, F. Serracino-Inglott, A. M. Jones, M. Kamalov, M. A. Brimble, F. L. Wilkinson and Y. Alexander, Heart, 2016, 102, Suppl 6, A132-A132. (IF = 6.0) DOI: 10.1136/heartjnl-2016-309890.196.

22. “Technology Advances for Pest Eradication” C. Eason, L. Shapiro, J. Ross, E. Murphy, S. Olgivie, D. MacMorran, M. Jackson, K. Irie, S. M. Clout, D. Rennison and M. A. Brimble, Proceedings of the 27th Vertebrate Pest Conference, R. M. Timm and R. A. Baldwin, Eds., 2016, 390-395.

21. “Development of New Chemical Probes for Investigation of the CB1-D2 Receptor Complex” N. Kahlcke, D. Furkert, M. Glass and M. A. Brimble, FEBS Journal, 2015, 282(supplement), 403-403.

20. “A Novel IGF-II-like Synthetic Peptide for Improving Tendon Healing” D. S. Musson, M. L. Tay, G. W. Williams, K. E. Callon, B. Coleman, M. A. Brimble, J. Cornish, Tissue Engineering Part A, 2015, 21(supplement), S355-S356.

19. “Retaining or Retrieving Older and Trying to Identify Novel Rodenticides” C. Eason, E. Murphy, S. Sam, J. Ross, H. Blackie, R. Henderson, L. Shapiro, D. MacMorran, T. Gibson, N. Gregory, D. Conole, D. Rennison, and M. A. Brimble, Proceedings of the 25th Vertebrate Pest Conference, R. M. Timm Ed., 2012, 149-150.

18. “A Slow-gradient, Sample-displacement Chromatography Approach for the Purification of Synthetic Peptides” J. M. Wojnar, P. W. R. Harris and M. A Brimble, Biotech International, 2012, 24, 22-25.

17. “Retrieving and Retaining Older and Advancing Novel Rodenticides as Alternatives to Anticoagulants” C. T. Eason, R. Henderson, E. Murphy, L. Shapiro, D. MacMorran, H. Blackie, M. Brimble, D. Conole, D. Rennison, T. J. Gibson and N. G. Gregory, Proceedings of the 8th European Vertebrate Pest Management Conference, 2011, 19-20.

16. “Development of NNZ-2566 as a Drug Candidate for Traumatic Brain Injury: The Neuren Story” M. A. Brimble and P. W. R. Harris, Chemistry in New Zealand, 2011, 75, 133-136. (Invited Paper from a Distinguished NZ scientist for Special Issue to Celebrate International Year of Chemistry”)

15. “Trends in Vertebrate Pesticide Use and New Developments: New Zealand Initiatives and International Implications” C. Eason, E. Murphy, S. Ogilivie, H. Blackie, J. Ross, M. Kaveramann, S. Sam, M. Statham, H. Statham, S. Lapidge, S. Humphrys, R. Henderson, D. MacMorran, T. Gibson, N. Gregory, J. Harrison, G. Giles, I. Summut, P. Jansen, D. Conole, D. Rennison, M. A. Brimble, Proceedings of 24th Vertebrate Pest Conference, 2010, 91-96.

14. “Toxicodynamics of Methemoglobin (MetHb) Inducers” C. Eason, M. A. Brimble, D. Rennison, M. D. Tingle, D. Conole, Proceedings of 24th Vertebrate Pest Conference, 2010, 108-114.

13. “Chemistry Research: Making Molecules for Medicines” M. A. Brimble, p864-865 in Chemistry, J. W. Wiley and Sons Australia, Ltd., eds. A. Blackman, S. E. Bottle, S. Schmid, M. Mocerino and U. Wille, 2008, ISBN 9 78047081 0866 (pbk).

12. “Science of Synthesis, Volume 28: Compounds with Two Carbon–Heteroatom Bonds: Quinones and Heteroatom Analogues” Volume editor A. G. Griesbeck. Georg Thieme Verlag: Stuttgart, 2006, 1006 pp, hardback. ISBN 3-13-118791-3 (RoW); ISBN 1-58890-460-1 (US). Book review by M. A. Brimble, Synthesis, 2007, 18, 2924.

11. “Equipment Access for Graduate Students – The First Hurdle” M. A. Brimble, Royal Society of New Zealand Alert Editorial, Issue 479, 5th July, 2007.

10. “Professor Jim Coxon. A Tribute” M. A. Brimble and P. Steel, Archive for Organic Chemistry (ARKIVOC), 2006, (iii), 1-5.

9. “Synthesis of Pharmaceuticals Using Molecular Chess and Automated Synthesis” M. A. Brimble, Chemistry in New Zealand, 2004, 68, 5-9.

8. “Turning Toxins into Medicines” M.A. Brimble and M. S. Levi, Chemistry in New Zealand, 2003, 66, No. 93, 18-24.

7. “Pushing Out Research Boundaries in Medicinal Chemistry” M. A. Brimble, New Zealand Pharmacy, 2002, 3, 15.

6. “Synthetic Studies Towards Natural Products Containing Bis-Spiroacetals” M. A. Brimble, Federation of Asian Chemical Societies Journal, 2002, 12-15.

5. “The Synthesis of Potential Chemotherapeutic Agents based on Leads from Nature” M. A. Brimble, Federation of Asian Chemical Societies Journal, 2001, 24-28.

4. “The Synthesis of Potential Chemotherapeutic Agents based on Leads from Nature” M. A. Brimble, Chemistry in Australia, 2001, 68, 15-17.

3. “Synthesis of Biologically Active Natural Products” M.A. Brimble, Chemistry in New Zealand, 1995, 58, 15-18.

2. “Apple Scald: Unravelling the Chemistry” M.A. Brimble, P. F. Reay, D. D. Rowan and J. A. Spicer, Chemistry in New Zealand, 1994, 58, 29-30.

1. “Strategic Synthesis : Science or Service” M.A. Brimble and D. D. Rowan, Chemistry in New Zealand, 1993, 57, 6-8.