Journal Articles

Prof Margaret Brimble has published over 500 articles and 60 reviews at internationally recognised journals and she is named as inventor in over 29 patents.

Journal Articles

2018

“Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin” R. Bower, L.  Yule, T. Rees, G. Deganutti, E. Hendrikse, P. Harris, R. Kowalczyk, Z. Ridgway, A. Wong, K. Swierkula, D. Raleigh, A. Pioszak, M. A. Brimble, C. Reynolds, C. Walker, D. Hay, ACS Pharmacology and Translational Science, 2018, 1, in press.

“The Role for Cyclic Glycine-Proline, a Biological Regulator of Insulin-like Growth Factor-1 in Pregnancy-related Obesity and Weight Changes” J. Guan, G. Singh-Mallah, K. Liu, E. Thorstensen, P. Shorten, E. A. Mitchell, R. Taylor, P. Harris, M. A. Brimble, J. M. D. Thompson and R. Murphy, Journal of Biological Regulators and Homeostatic Agents, 2018, 32, 11-25.

“Desacetyl-a-melanocyte Stimulating Hormone and a-Melanocyte Stimulating Hormone are required to Regulate Energy Balance” K. G. Mountjoy, A. Caron, K. Hubbard, A. Shome, A. C. Grey, B. Sun, S. Bould, M. Middleditch, B. Pontré, A. McGregor, P. W.R. Harris, R. Kowalczyk, M. A. Brimble, R. Botha1, K. M. L. Tan, S. J. Piper, C. Buchanan, S. Lee, A. P. Coll and J. K. Elmquis, Molecular Metabolism, 2018, 9, 207-216.

“Total Synthesis of (-)-Peniphenone A” M. Pantin, M. A. Brimble and D. P. Furkert, Journal of Organic Chemistry, 2018, 83, in press

“Using Chemical Synthesis to Probe Structure-Activity Relationships of the Glycoactive Bacteriocin Glycocin F” S. Bisset, S.-H. Yang, Z. Amso, P. Harris, M. Patchett, M. A. Brimble and G. Norris, ACS Chemical Biology, 2018, 13, in press.

“A Double-click Approach to the Protecting Group Free Synthesis of Glycoconjugates” S. R. Alexander, G. M. Williams, M. A. Brimble and A. J. Fairbanks, Organic and Biomolecular Chemistry, 2018, 16, 1258-1262.

“Receptor Activity-Modifying Proteins have Limited Effects on the Class B G Protein-Coupled Receptor Calcitonin Receptor-like Receptor Stalk” M. Garelja, C. Walker, A. Siow, S. Yang, P. Harris, M. A. Brimble, H. Watkins, J. Gingell and D. Hay, Biochemistry, 2018, in press

“Total Synthesis and Conformational Study of The Anti-tubercular Cyclic Peptide Callyaerin A Bearing a Rare Rigidifying (Z)-2,3-Diaminoacrylamide Moiety” M. A. Brimble, S. Zhang, L. M. De Leon Rodriguez, I. K. H. Leung, G. M. Cook and  P. W. R. Harris Angewandte Chemie International Edition, 2018, 57, 3631-3635

Cover Article and VIP paper

“Total Synthesis of the Highly N-Methylated Acetylene-Containing Anticancer Peptide Jahanyne,” A. Siow, G. Opiyo, I. Kavianinia, F. F. Li, D. P. Furkert, P. W. R Harris and M. A. Brimble, Organic Letters, 2018, 20, 788-791

“Total Chemical Synthesis of Glycocin F and Analogues: S-Glycosylation Confers Improved Antimicrobial Activity” Z. Amso, S. W. Bisset, S.-H. Yang, P. W. R. Harris, T. H. Wright, C. D. Navo, M. L. Patchett, G. E. Norris and M. A. Brimble, Chemical Science, 2018, 9, 1686-1691.

“Anthranilate Phosphoribosyltransferase: Binding Determinants for 5′-Phospho-alpha-D-ribosyl-1′-pyrophosphate (PRPP) and the Implications for Inhibitor Design”
G. L. Evans, D. P. Furkert, N. Abermil, P. Kundu, K. M. de Lange, E. J. Parker, M. A. Brimble, E. N. Baker and J. S. Lott,
Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics, 2018, 1866, 264-274.
https://doi.org/10.1016/j.bbapap.2017.08.018

2017

“Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid-Peptide Vaccine”
R. J. Anderson, J. Li, L. Kedzierski, B. J. Compton, C. M. Hayman, T. L. Osmond, C.-W. Tang, K. J. Farrand, H.-F. Koay, C. F. Dos Santos Sa E. Almeida, L. R. Holz, G. M. Williams, M. A. Brimble, Z. Wang, M. Koutsakos, K. Kedzierska, D. I. Godfrey, I. F. Hermans, S. J. Turner and G. F. Painter,
ACS Chemical Biology, 2017, 12, 2898-2905.
http://doi.org/10.1021/acschembio.7b00845

“N-Acetylcysteine Counteracts Adipose Tissue Macrophage Infiltration and Insulin Resistance Elicited by Advanced Glycated Albumin in Healthy Rats”
K. S. Da Silva, P. R. Pinto, N. T. Fabre, D. J. Gomes, K. Thieme, L. S. Okuda, R. T. Iborra, V. G. Freitas, M. H. M. Shimizu, W. R. Teodoro, S. K. N. Marie, T. Woods, M. A Brimble, R. Pickford, K.-A. Rye, M. Okamoto, S. Catanozi, M. L. Correa-Giannela, U. F. Machado, and M. Passarelli,
Frontiers in Physiology, 2017, 8, 723.

Open access http://doi.org/10.3389/fphys.2017.00723

“Stereochemical Characterisation of Polyketide Stereotriads Synthesized via Hydrogen Mediated Asymmetric syn-Crotylation”
M. Pantin, J. G. Hubert, T. Söhnel, M. A. Brimble and D. P. Furkert,
Journal of Organic Chemistry, 2017, 82, 11225-11229.
http://doi.org/10.1021/acs.joc.7b01820

“Synthesis and Biological Evaluation of Novel Teixobactin Analogues”
C. E. Schumacher, P. W. R. Harris, X.-B. Ding, B. Krause, T. H. Wright, G. M. Cook, D. P. Furkert and M. A. Brimble,
Organic and Biomolecular Chemistry, 2017, 15, 8755-8760.
http://doi.org/10.1039/c7ob02169k

“General Synthesis of the Nitropyrrolin Family of Natural Products via Regioselective CO₂-Mediated Alkyne Hydration”
X.-B. Ding, D. P. Furkert and M. A. Brimble,
Organic Letters, 2017, 19, 5418-5421.
http://doi.org/10.1021/acs.orglett.7b02687

“Understanding the Metal Mediated Assembly and Hydrogel Formation of a beta-Hairpin Peptide”
L. M. De Leon Rodriguez, Y. Hemar, A. K. Mitra and M. A. Brimble,
Biomaterials Science, 2017, 5, 1993-1997.
http://doi.org/10.1039/c7bm00512a

“Synthesis and Incorporation of an Advanced Lipid Peroxidation End-Product Building Block into Collagen Mimetic Peptides”
I. Kavianinia, S.‐H. Yang, H. Kaur, P. W. R. Harris, R. C. J. Dobson, A. J. Fairbanks and M. A. Brimble,
Chemical Communications, 2017, 53, 8459-8462.
http://doi.org/10.1039/c7cc05025a

“Incorporation of ‘Click’ Chemistry Glycomimetics Dramatically Alters Triple-Helix Stability in an Adiponectin Model Peptide”
K. R. Lutteroth, P. W. R. Harris, T. H. Wright, H. Kaur, K. Sparrow, S.-H. Yang, G. J. S. Cooper and M. A. Brimble,
Organic and Biomolecular Chemistry, 2017, 15, 5602-5608.
http://doi.org/10.1039/c7ob01388d

“Bioinspired Total Synthesis and Stereochemical Revision of the Fungal Metabolite Pestalospirane B”
S. Badrinarayanan, C. J. Squire, J. Sperry and M. A. Brimble,
Organic Letters, 2017, 19, 3414-3417.
http://doi.org/10.1021/acs.orglett.7b01371

“Total Synthesis and Stereochemical Revision of the 2-Formylpyrrole Alkaloid Hemerocallisamine I”
J. M. Wood, D. P. Furkert and M. A. Brimble,
Journal of Natural Products, 2017, 80, 1926-1929.
http://doi.org/10.1021/acs.jnatprod.7b00314

“Norborn-2-en-7-ones as Physiologically-Triggered Carbon Monoxide-Releasing Prodrugs”
J. T. B. Kueh, N. J. Stanley, R. J. Hewitt, L. M. Woods, L. Larsen, J. C. Harrison, D. Rennison, M. A. Brimble, I. A. Sammut, and D. S. Larsen,
Chemical Science, 2017, 8, 5454-5459.

Open access http://doi.org/10.1039/c7sc01647f

“Remarkable Influence of Cobalt Catalysis on Epoxide Ring-Opening with Sulfoxonium Ylides”
M. L. Jamieson, N. Z. Brant, M. A. Brimble and D. P. Furkert,
Synthesis, 2017, 49, 3952-3956.
http://doi.org/10.1055/s-0036-1588814

Invited Feature Article and Special Topic “Cobalt in Organic Synthesis” Cover Page, Synthesis, 2017, 49, 3885; http://doi.org/10.1055/s-0036-1589510

“Stability of Polyelectrolyte-Coated Iron Nanoparticles for T₂-Weighted Magnetic Resonance Imaging”
A. J. McGrath, C. Dolan, S. Cheong, D. A. J. Herman, B. Naysmith, F. Zong, P. Galvosas, K. J. Farrand, I. F. Hermans, M. A. Brimble, D. E. Williams, J. Jin, R. Tilley and R. D. Herman,
Journal of Magnetism and Magnetic Materials, 2017, 439, 251-258.
https://doi.org/10.1016/j.jmmm.2017.04.026

“Structure-Activity Relationship Study of the Tumour-Targeting Peptide A20FMDV2 via Modification of Lys16, Leu13, and N– and/or C-Terminal Functionality”
K.-Y. Hung, P. W. R. Harris, A. Desai, J. F. Marshall and M. A. Brimble,
European Journal of Medicinal Chemistry, 2017, 136, 154-164.
https://doi.org/10.1016/j.ejmech.2017.05.008

“Unexpected Direct Synthesis of N-Vinyl Amides Through Vinyl Azide-Enolate [3+2] Cycloaddition”
H. Choi, H. J. Shirley, P. A. Hume, D. P. Furkert and M. A. Brimble,
Angewandte Chemie International Edition, 2017, 56, 7420-7424.
http://doi.org/10.1002/anie.201702727

“Protecting Group Free Synthesis of Glycosyl Thiols from Reducing Sugars in Water; Application to the Production of N-Glycan Glycoconjugates”
S. R. Alexander, D. Lim, Z. Amso, M. A. Brimble and A. J. Fairbanks,
Organic and Biomolecular Chemistry, 2017, 15, 2152-2156.

Open access http://doi.org/10.1039/c7ob00112f

“MALDI-Imaging Enables Direct Observation of Kinetic and Thermodynamic Products of Mixed Peptide Fiber Assembly”
K. Medini, B. West, D. E. Williams, M. A. Brimble and J. A. Gerrard,
Chemical Communications, 2017, 53, 1715-1718.
http://doi.org/10.1039/c6cc10146a

“Cyclization of Linear Tetrapeptides Containing N-Methylated Amino Acids by Using 1-Propanephosphonic Acid Anhydride”
S. Zhang, L. M. De Leon Rodriguez, E. Lacey, A. M. Piggott, I. K. H. Leung and M. A. Brimble,
European Journal of Organic Chemistry, 2017, 149-158.
http://doi.org/10.1002/ejoc.201601016

“An Efficient Chemical Synthesis of Lassomycin Enabled by an On-resin Lactamisation–Off-resin Methanolysis Strategy and Preparation of Chemical Variants”
P. W. R. Harris, G. M. Cook, I. K. H. Leung and M. A. Brimble,
Australian Journal of Chemistry, 2017, 70, 172-183.
https://doi.org/10.1071/CH16499

Invited Article for Special Edition on “Peptide Chemistry”

“Solid-Phase Synthesis of the Peptaibol Alamethicin U-22324 Using a Double-Linker Strategy”
A. Siow, K.-Y. Hung, P. W. R. Harris and M. A. Brimble,
European Journal of Organic Chemistry, 2017, 350-354.
http://doi.org/10.1002/ejoc.201601102

“Characterizing the Mode of Action of Extracellular Connexin43 Channel Blocking Mimetic Peptides in an in vitro Ischemia Injury Model”
Y. Kim, J. M. Griffin, P. W. R. Harris, S. H. C. Chan, L. F. B. Nicholson, M. A. Brimble, S. J O’Carroll and C. R. Green,
Biochimica and Biophyscia Acta (General), 2017, 1861, 68-78.
http://doi.org/10.1016/j.bbagen.2016.11.001

“Multifunctional Thermoresponsive Designer Peptide Hydrogels”
L. M. De Leon Rodriguez, Y. Hemar, G. Mo, A. K. Mitra, J. Cornish and M. A. Brimble,
Acta Biomaterialia, 2017, 47, 40-49.
http://doi.org/10.1016/j.actbio.2016.10.014

2016

“2-Nitropyrrole Cross-Coupling Enables a Second Generation Synthesis of the Heronapyrrole Antibiotic Natural Product Family”
X. Ding, D. P. Furkert and M. A. Brimble,
Chemical Communications, 2016, 52, 12638-12641.
http://doi.org/10.1039/c6cc07532k

“A NBD Derivative of the Selective Rat Toxicant Norbormide as a New Probe for Living Cell Imaging”
C. D’Amore, G. Orso, F. Fusi, M. A. Pagano, G. Miotto, A. Forgiarini, S. De Martin, G. Castellani, G. Ribaudo, D. Rennison, M. A. Brimble, B. Hopkins, A. Ferrarese and S. Bova,
Frontiers in Pharmacology (Experimental Pharmacology and Drug Discovery), 2016, 7(315), 1-13.

Open Access: http://dx.doi.org/10.3389/fphar.2016.00315

“Cyclic Enecarbamates as Precursors of alpha,beta-Unsaturated Iminium Ions: Reactivity and Synthesis of 6,6-Spirocyclic Ring Systems”
Z. Wang, N. Krogsgaard-Larsen, B. Daniels, D. P. Furkert and M. A. Brimble,
Journal of Organic Chemistry, 2016, 81, 10366-10375.
http://doi.org/10.1021/acs.joc.6b01343

“Glycated Albumin Induces Lipid Infiltration in Mice Aorta Independently of DM and RAS Local Modulation by Inducing Lipid Peroxidation and Inflammation”
D. J. Gomes, A. P. Velosa, L. S. Okuda, F. B. Fusco, K. S. da Silva, P. R. Pinto, E. R. Nakandakare, M. L. Correa-Giannella, T. Woods, M. A. Brimble, R. Pickford, K.-A. Rye, W. R. Teodoro, S. Catanozi and M. Passarelli,
Journal of Diabetes and Its Complications, 2016, 30, 1614-1621.
http://dx.doi.org/10.1016/j.jdiacomp.2016.07.001

“Structure Activity Relationship Study on the Peptide Hormone Preptin, a Novel Bone-anabolic Agent for the Treatment of Osteoporosis”
Z. Amso, R. Kowalczyk, M. Watson, Y.-E. Park, K. E. Callon, D. S. Musson, J. Cornish and M. A. Brimble,
Organic and Biomolecular Chemistry, 2016, 14, 9163-9440.
http://doi.org/10.1039/c6ob01455k

Selected for “Front Cover”

“Total Synthesis and Stereochemical Revision of the Anti-Tuberculosis Peptaibol Trichoderin A”
I. Kavianinia, L. Kunalingam, P. W. R. Harris, G. M. Cook and M. A. Brimble,
Organic Letters, 2016, 18, 3878-3881.

Open access http://doi.org/10.1021/acs.orglett.6b01886

“Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol”
R. Quach, D. P. Furkert and M. A. Brimble,
Journal of Organic Chemistry, 2016, 81, 8343-8350.
http://doi.org/10.1021/acs.joc.6b01503

“Synthesis of Psychrophilin E”
S. T. Y. Ngen, H. Kaur, P. A. Hume, D. P. Furkert and M. A. Brimble,
Journal of Organic Chemistry, 2016, 81, 7635-7643.
http://doi.org/10.1021/acs.joc.6b01369

“Synthesis of the 2-Formylpyrrole Spiroketal Pollenopyrroside A and Structural Elucidation of Xylapyrroside A, Shensongine A and Capparisine B”
J. M. Wood, D. P. Furkert and M. A. Brimble,
Organic and Biomolecular Chemistry, 2016, 14, 7569-7664.
http://doi.org/10.1039/c6ob01361a

“Maternally Administered Cyclic Glycine-Proline Increases Insulin-like Growth Factor-1 Bioavailability and Novelty Recognition in Developing Offspring”
G. Singh-Mallah, K. Singh, C. D. McMahon, P. W. R. Harris, M. A. Brimble, E. Thorstensen and J. Guan,
Endocrinology, 2016, 157, 3130-3139.
http://doi.org/10.1210/en.2016-1189

“Synthesis and Biological Evaluation of Analogues of the Potent ADAM8 Inhibitor Cyclo(RLsKDK) for the Treatment of Inflammatory Diseases and Cancer Metastasis”
V. Yim, A. F. M. Noisier, K.-Y. Hung, J. W. Bartsch, U. Schlomann and M. A. Brimble,
Bioorganic and Medicinal Chemistry, 2016, 24, 4032-4037.
http://dx.doi.org/10.1016/j.bmc.2016.06.042

“Stereoselective Synthesis of the Rat Selective Toxicant Norbormide”
M. Jay-Smith, E. C. Murphy, L. Shapiro, C. T. Eason, M. A. Brimble and D. Rennison,
Tetrahedron, 2016, 72, 5331-5342.
http://dx.doi.org/10.1016/j.tet.2016.07.014

“Synthesis of Natural Cyclopentapeptides Isolated from Dianthus chinensis”
S. Zhang, Z. Amso, L. M. De Leon Rodriguez, H. Kaur and M. A. Brimble,
Journal of Natural Products, 2016, 79, 1769−1774.
http://doi.org/10.1021/acs.jnatprod.6b00152

“Identification of Anticancer Agents Based on the Thieno[2,3-b]pyridine and 1H-Pyrazole Molecular Scaffolds”
C. Eurtivong, I. Reynisdóttir, S. Kuczma, D. P. Furkert, M. A. Brimble and J. Reynisson,
Bioorganic and Medicinal Chemistry, 2016, 24, 3521-3526.
http://dx.doi.org/10.1016/j.bmc.2016.05.061

“Synthesis and in vitro Bone Cell Activity of Analogues of the Cyclohexapeptide Dianthin G”
Z. Amso, R. Kowalczyk, Y.-E. Park, M. Watson, J.-M. Lin, D. S. Musson, J. Cornish and M. A. Brimble,
Organic and Biomolecular Chemistry, 2016, 14, 6231-6243.
http://doi.org/10.1039/c6ob00983b

Invited article for “Selective Chemistry with Peptides and Proteins” themed issue edited by Professor Phil Dawson

“Isolation, Structural Elucidation and Synthesis of Lepteridine from Mānuka (Lepstospermum scoparium) Honey”
B. J. Daniels, G. Prijic, S. Meidinger,  K. M. Loomes, J. M. Stephens, R. C. Schlothauer, D. P. Furkert and M. A. Brimble,
Journal of Agricultural and Food Chemistry, 2016, 64, 5079–5084.
http://doi.org/10.1021/acs.jafc.6b01596

“Controlling Gelation with Sequence: Towards Programmable Peptide Hydrogels”
K. Medini, B. W. Mansel, M. A. K. Williams, M. A. Brimble, D. E. Williams, J. A. Gerrard,
Acta Biomaterialia, 2016, 43, 30-37.
http://dx.doi.org/10.1016/j.actbio.2016.07.021

“Substituted Carbazoles – A New Class of Anthelmintic Agent”
D. Rennison, S. M. Gueret, O. Laita, R. J. Bland, I. A. Sutherland, I. K. Boddy and M. A. Brimble,
Australian Journal of Chemistry, 2016, 69, 1268-1276.
http://dx.doi.org/10.1071/CH16169

“Synthesis and Amylin Receptor Activity of Glycomimetics of Pramlintide using Click Chemistry”
L. R. Yule, R. L. Bower, H. Kaur, R. Kowalczyk, D. L. Hay and M. A. Brimble,
Organic and Biomolecular Chemistry, 2016, 14, 5238-5245.
http://doi.org/10.1039/c6ob00850j

Invited article for “Selective Chemistry with Peptides and Proteins” themed issue edited by Professor Phil Dawson; Selected for “Front Cover”.

“Radiation Damage and Racemic Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily”
H. Yeung, C. J. Squire, Y. Yosaatmadja, S. Panjikar, G. López, A. Molina, E. N. Baker, P. W. R. Harris and M. A. Brimble,
Angewandte Chemie International Edition, 2016, 55, 7930-7933.
http://doi.org/10.1002/anie.201602719

Selected for “Front Cover” and as “VIP paper” <5% of accepted papers receive this accolade

“Receptor Activity-Modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties”
H. A. Watkins, M. Chakravarthy, R. S. Abhayawardana, J. J. Gingell, M. Garelja, M. Pardamwar, J. M. W. R. McElhinney, A. Lathbridge, A. Constantine, P. W. R.  Harris, T.-Y. Yuen, M. A. Brimble, J. Barwell, D. R. Poyner, M. J. Woolley, A. C. Conner, A. A. Pioszak, C. A. Reynolds and D. L. Hay,
Journal of Biological Chemistry, 2016, 291, 11657-11675.

Open Access: http://www.jbc.org/content/291/22/11657

“Fatty Acid Derived Pro-toxicants of the Rat Selective Toxicant Norbormide”
H. Choi, D. Conole, D. J. Atkinson, O. Laita, M. Jay-Smith, M. A. Pagano, G. Ribaudo, M. Cavalli, S. Bova, B. Hopkins, M. A. Brimble and D. Rennison,
Chemistry and Biodiversity, 2016, 13, 762-775.
http://doi.org/10.1002/cbdv.201500241

“Synthesis and Structural Insight into ESX-1 Substrate Protein C, an Immunodominant Mycobacterium Tuberculosis-Secreted Antigen”
S. J. Son, P. W. R. Harris, C. J. Squire, E. N. Baker and M. A. Brimble,
Biopolymers (Peptide Science), 2016, 106, 267-274.
http://doi.org/10.1002/bip.22838

Lipidation of Cysteine or Cysteine-Containing Peptides Using the Thiol-ene Reaction (CLipPA)”
S.-H. Yang, P. W. R. Harris, G. M. Williams and M. A. Brimble,
European Journal of Organic Chemistry, 2016, 2608-2616.
http://doi.org/10.1002/ejoc.201501375

Selected for “Front Cover”

“A New High-Capacity Metal Ion-Complexing Gel Containing Cyclen Ligands”
C. Dolan, F. Douret, D. C. Ware, P. J. Brothers, J. Jin, M. A. Brimble and D. Williams,
RSC Advances, 2016, 6, 23645-23652.
http://doi.org/10.1039/c6ra00604c

“A Peptide Hydrogel Derived from a Fragment of Human Cardiac Troponin C”
L. M. De Leon-Rodriguez, M. Kamalov, Y. Hemar, A. K. Mitra, V. Castelletto, D. Hermida-Merino, I. W. Hamley and M. A. Brimble,
Chemical Communications, 2016, 52, 4056-4059.
http://doi.org/10.1039/c6cc00209a

“Fluorescent IGF-II Analogues for FRET-Based Investigations into the Binding of IGF-II to the IGF-1R”
J. M. Cottam Jones, P. W. R. Harris, D. B. Scanlon, B. E. Forbes, M. A. Brimble and A. D. Abell,
Organic and Biomolecular Chemistry, 2016, 14, 2698-2705.
http://doi.org/10.1039/c5ob02110c

“Divergent Reactivity via Cobalt Catalysis: An Epoxide Olefination”
M. L. Jamieson, P. A. Hume, D. P. Furkert and M. A. Brimble,
Organic Letters, 2016, 18, 468-471.

Open access http://doi.org/10.1021/acs.orglett.5b03514

“The Nedd4-1 WW Domain Recognizes the PY Motif Peptide through a Coupled Folding and Binding Equilibrium”
V. Panwalkar, P. Neudecker, M. Schmitz, J. Lecher, M. Schulte, K. Medini, M. Stoldt, M. A.  Brimble, D. Willbold and A. Dingley,
Biochemistry, 2016, 55, 659-674.
http://doi.org/10.1021/acs.biochem.5b01028

“Enantioselective Synthesis of BE Ring Analogues of Methyllycaconitine”
E. Dickson, L. I. Pilkington, M. A. Brimble and D. Barker,
Tetrahedron, 2016, 72, 400-414.
http://dx.doi.org/10.1016/j.tet.2015.11.057

“Synthesis and Activity of a Diselenide Bond Mimetic of the Antimicrobial Protein Caenopore-5”
K. Medini, P. W. R. Harris, A. Menorca, K. Hards, G. M. Cook and M. A. Brimble,
Chemical Science, 2016, 7, 2005-2010.

Open Access: http://pubs.rsc.org/en/Content/ArticleLanding/2016/SC/C5SC04187B

“Electrochemically-controlled Grafting of Hydrophilic Brushes from Conducting Polymer Substrates”
L. T. Strover, J. Malmström, L. Stubbing, M. A. Brimble and J. Travas-Sejdic,
Electrochimica Acta, 2016, 188, 57-70.
http://dx.doi.org/10.1016/j.electacta.2015.11.106

“A Convergent Synthesis of Gonytolide C Using an Intramolecular Oxa-Michael Addition”
F. F. Li, D. J. Atkinson, D. P. Furkert and M. A. Brimble,
European Journal of Organic Chemistry, 2016, 33, 1145-1155.
http://doi.org/10.1002/ejoc.201501402

“Peptide Binding to a Bacterial Signal Peptidase Visualized by Peptide Tethering and Carrier-driven Crystallization”
Y. T. Ting, P. W. R. Harris, G. Batot, M. A. Brimble, E. N. Baker and P. G. Young,
International Union of Crystallography Journal, 2016, 3, 10-19.

Open Access: http://dx.doi.org/10.1107/S2052252515019971

“Synthesis of the Spiroketal Core of the Pinnatifinoside Family of Natural Products”
D. F. Chorley, D. P. Furkert and M. A. Brimble,
European Journal of Organic Chemistry, 2016, 314-319.
http://doi.org/10.1002/ejoc.201501225

2015

“Total Synthesis and Structural Confirmation of the Antimalarial Naphthopyrone Lasionectrin”
V. L. Poral, D. P. Furkert and M. A. Brimble,
Organic Letters, 2015, 17, 6214-6217.

“Glicentin-Related Pancreatic Polypeptide Inhibits Glucose-Stimulated Insulin Secretion from the Isolated Pancreas of Adult Male Rats”
L. Whiting, K. W. Stewart, D. L. Hay, P. W. R. Harris, Y. S. Choong, A. R. J. Phillips, M. A. Brimble and G. J. S. Cooper,
Physiological Reports, 2015, 3, e12638. 1-12.

Open Access: http://physreports.physiology.org/content/3/12/e12638

“NKT Cell-Dependent Glycolipid-Peptide Vaccines with Potent Anti-Tumour Activity”
R. J. Anderson, B. J. Compton, C.-W. Tang, A. Authier-Hall, C. M. Hayman, G. W. Swinerd, R. Kowalczyk, P. W. R. Harris, M. A Brimble, D. S. Larsen, O. Gasser, R. Weinkove, I. F. Hermans and G. F. Painter,
Chemical Science, 2015, 6, 5120-5127.

Open Access: http://pubs.rsc.org/en/Content/ArticleLanding/2015/SC/c4sc03599b#!divAbs…

Selected as an Edge Article and Front Cover

“Convergent Chemo-Enzymatic Synthesis of Mannosylated Glycopeptides; Targeting of Putative Vaccine Candidates to Antigen Presenting Cells”
J. D. MacIntosh, M. A. Brimble, A. E. S. Brooks, P. R. Dunbar, R. Kowalczyk, Y. Tomabechi and A. J. Fairbanks,
Chemical Science, 2015, 6, 4636-4642.

Open Access: http://pubs.rsc.org/en/Content/ArticleLanding/2015/SC/C5SC00952A

“Improved Synthesis of the Unnatural Amino Acids AHMOD and AMD, Components of the Anticancer Peptaibol Culicinin D”
K.-Y. Ko, S. Wagner, S.-H. Yang, D. P. Furkert and M. A. Brimble,
Journal of Organic Chemistry, 2015, 80, 8631-8636.

“Improved Strategy for the Synthesis of the Anticancer Agent Culicinin D”
M. Stach, A. J. Weidkamp, S.-H. Yang, K.-Y. Hung, D. P. Furkert, P. W. R. Harris, J. B. Smaill, A. V. Patterson and M. A. Brimble,
European Journal of Organic Chemistry, 2015, 6341-6350.

“Synthesis of DOHNAA, a Mycobacterium tuberculosis Cholesterol CD Ring Catabolite and FadD3 Substrate”
L. A. Stubbing, J. S. Lott, S. S. Dawes, D. P. Furkert and M. A. Brimble,
European Journal of Organic Chemistry, 2015, 32, 6075-6083.

“Regulation and Quality Control of Adiponectin Assembly by Endoplasmic Reticulum Chaperone ERp44”
L. Hampe, M. Radjainia, C. Xu, P. W. R. Harris, G. Bashiri, D. C. Goldstone, M. A. Brimble, Y. Wang and A. K. Mitra,
Journal of Biological Chemistry, 2015, 290, 18111-18123.

“Cell-Targeted Platinum Nanoparticles and Nanoparticle Clusters”
S. Papst, M. A. Brimble, C. W. Evans, D. J. Verdon, V. Feist, P. R. Dunbar, R. D. Tilley and D. E. Williams,
Organic and Biomolecular Chemistry, 2015, 13, 6567-6572.

“On Resin Synthesis and Cross-linking of Collagen Peptides Containing the Advanced Glycation End-product Pyrraline via Maillard Condensation”
M. Kamalov, P. W. R. Harris, J. M. Wood and M. A. Brimble,
Chemical Communications, 2015, 51, 9475-9478.

“Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G protein-Coupled Receptor”
J. M. Booe, C. S. Walker, J. Barwell, G. Kuteyi, J. Simms, M. A. Jamaluddin, M. L. Warner, R. M. Bill, P. W. R. Harris, M. A. Brimble, D. R. Poyner, D. L. Hay and A. A. Pioszak,
Molecular Cell, 2015, 58, 1040-1052.

“Diabetes-Induced Alterations in Tissue Collagen and Carboxymethyllysine in Rat Kidneys: Association with Increased Collagen-Degrading Proteinases and Amelioration by Cu(II)-Selective Chelation”
S. Brings, S. Zhang, Y. S Choong, S. Hogl, M. Middleditch, M. Kamalov, M. A Brimble, D. Gong and G. J. S. Cooper,
Biochimica and Biophysica Acta (BBA) – Molecular Basis of Disease, 2015, 1852, 1610-1618.

“Replacement of the CysA7-CysB7 Disulfide Bond with a 1,2,3-Triazole Linker Causes Unfolding in Insulin Glargine”
G. M. Williams, K. Lee, X. Li, G. J. S. Cooper and M. A. Brimble,
Organic and Biomolecular Chemistry, 2015, 13, 4059-4063.

“Studies Towards Development of Asymmetric Double-Mannich Reactions of Chiral 2-Oxocyclohexanecarboxylate Derivatives with Bis(aminol)ethers”
K. J. Sparrow, S. Carley, T. Söhnel, D. Barker and M. A. Brimble,
Tetrahedron, 2015, 71, 2210-2221.

“Chemical Synthesis of a Polypeptide Backbone Derived from the Primary Sequence of the Cancer Protein NY-ESO-1 Enabled by Kinetically Controlled Ligation and Pseudoprolines”
P. W. R. Harris and M. A. Brimble,
Biopolymers (Peptide Science), 2015, 104, 116-127.

“Preparation of cis-gamma-Hydroxycarvone Derivatives for Synthesis of Sesterterpenoid Natural Products: Total Synthesis of Phorbin A”
J. G. Hubert, D. P. Furkert and M. A. Brimble,
Journal of Organic Chemistry, 2015, 80, 2231-2239.

Open access http://doi.org/10.1021/jo502897u

“Synthesis of the Spirocyclic Framework of Sesterterpenoid Natural Products”
J. G. Hubert, D. P. Furkert and M. A. Brimble,
Journal of Organic Chemistry, 2015, 80, 2715-2723.

“Physicochemical Studies on the Copper(II) Binding by Glycated Collagen Telopeptides”
M. Kamalov, P. W. R. Harris, C. G. Hartinger, G. M. Miskelly, G. J. S. Cooper and M. A. Brimble,
Organic and Biomolecular Chemistry, 2015, 13, 3058-3063.

“Total Synthesis of the Cyclic Depsipeptide YM-280193, a Platelet Aggregation Inhibitor”
H. Kaur, P. W. R. Harris, P. J. Little and M. A. Brimble,
Organic Letters, 2015, 17, 492-495.

Open access: http://pubs.acs.org/doi/abs/10.1021/ol503507g

“Synthesis of Novel Triazole-Containing Phosphonate Polymers”
C. Dolan, B. Naysmith, S. F. R. Hinkley, I. M. Sims, M. A. Brimble, D. E. Williams and J. Jin,
Australian Journal of Chemistry, 2015, 68, 680-686.

“Using Mass Spectrometry to Detect, Differentiate and Semiquantitate Closely Related Peptide Hormones in Complex Milieu: Measurement of IGF-II and Vesiculin”
K. L. Lee, M. J. Middleditch, G. M. Williams, M. A. Brimble and G. J. S. Cooper,
Endocrinology, 2015, 156, 1194-1199.

“Synthesis of the Antimicrobial S-Linked Glycopeptide, Glycocin F”
M. A. Brimble, P. J. Edwards, P. W. R. Harris, G. E. Norris, M. L. Patchett, T. H. Wright, S.-H. Yang, and S. E. Carley,
Chemistry – A European Journal, 2015, 21, 3556-3561.

“Chemical Synthesis of gamma-Secretase Activating Protein Using Pseudo-Glutamines as Ligation Sites”
P. W. R. Harris, C. Squire, P. G. Young and M. A. Brimble,
Biopolymers (Peptide Science), 2015, 104, 37-45.

“Neuroprotection with Glycine-2-Methylproline-Glutamate (G-2MePE) after Hypoxic-Ischemic Brain Injury in Adult Rats,”
S. Mathai, P. W. R. Harris, M. A. Brimble, A. J. Gunn and J. Guan,
Journal of Experimental Stroke and Translational Medicine, 2015, 6, 1-11.

“Virtual Screening for Novel Atg5-Atg16 Complex Inhibitors for Autophagy Modulation”
E. Robinson, E. Leung, A. M. Matuszek, N. Krogsgaard-Larsen, D. P. Furkert, M. A. Brimble, A. Richardson and J. Reynisson,
MedChemComm, 2015, 6, 239-246.

“Chemical Synthesis of a Pore-Forming Antimicrobial Protein, Caenopore-5, by Using Native Chemical Ligation at a Glu-Cys Site”
K. Medini, P. W. R. Harris, K. Hards, A. J. Dingley, G. M. Cook and M. A. Brimble,
ChemBioChem, 2015, 16, 328-336.

“Chemical Synthesis of a Pore-Forming Antimicrobial Protein, Caenopore-5, by Using Native Chemical Ligation at a Glu-Cys Site”
K. Medini, P. W. R. Harris, K. Hards, A. J. Dingley, G. M. Cook and M. A. Brimble,
ChemBioChem, 2015, 16, 328-336.

“Formal Synthesis of Nanaomycin D via a Hauser-Kraus Annulation Using a Chiral Enone-Lactone”
N. P. S. Hassan, B. J. Naysmith, J. Sperry and M. A. Brimble,
Tetrahedron, 2015, 71, 7137-7143.

Invited Article for Tetrahedron Special Edition in memory of Professor Alan Katritzky

2014

“Synthesis of the Carbon Skeleton of the Griseorhodins”
D. J. Atkinson, D. P. Furkert and M. A. Brimble,
Tetrahedron, 2015, 71, 91-101.

“Nonsymmetrical Azocarbonamide Carboxylates as Effective Mitsunobu Reagents”
D. P. Furkert, B. Breitenbach, L. Juen, I. Sroka, M. Pantin and M. A. Brimble,
European Journal of Organic Chemistry, 2014, 7806-7809.

“Total Synthesis of the Macrocyclic N-Methyl Enamides Palmyrolide A and 2S-Sanctolide A”
A. D. Wadsworth, D. P. Furkert and M. A. Brimble,
Journal of Organic Chemistry, 2014, 79, 11179-11193.

“Synthesis and Evaluation of 9-Deoxy Analogues of (–)-Thysanone, an Inhibitor of HRV 3C Protease”
J. Y. Jeong, J. Sperry, J. A. Taylor and M. A. Brimble,
European Journal of Medicinal Chemistry, 2014, 87, 220-227.

“Protecting-Group-Free One-pot Synthesis of Glycoconjugates Directly from Reducing Sugars”
D. Lim, M. A. Brimble, R. Kowalczyk, A. J. A. Watson and A. J. Fairbanks,
Angewandte Chemie International Edition, 2014, 53, 11907-11911.

“Synthesis of the Revised Structure of Acortatarin A”
H. M. Geng, L. A. Stubbing, J. L.-Y. Chen, D. P. Furkert and M. A. Brimble,
European Journal of Organic Chemistry, 2014, 31, 6227-6241.

“Convergent Chemoenzymatic Synthesis of a Library of Glycosylated Analogues of Pramlintide: Structure-Activity Relationships of Amylin Receptor Agonism”
R. Kowalczyk, M. A. Brimble, Y. Tomabechi, A. J.  Fairbanks, M. Fletcher and D. L. Hay,
Organic and Biomolecular Chemistry, 2014, 12, 8142-8151.

Selected for front cover

“Toward an Asymmetric Synthesis of the Dimeric Pyranonaphthoquinone Antibiotic Crisamicin A”
M. A. Brimble, N. P. S. Hassan, B. J. Naysmith and J. Sperry,
Journal of Organic Chemistry, 2014, 79, 7169-7178.

“An Efficient Fmoc Solid-Phase Synthesis of an Amphiphile of the Neuroprotecive Agent Glycyl-prolyl-glutamic acid”
P. W. R. Harris, G. T. Molenaar, Z. Amso, G. P. Savage and M. A. Brimble,
Synlett, 2014, 25, 2221-2224.

“Total Synthesis of Virgatolide B via Exploitation of Intramolecular Hydrogen Bonding”
P. A. Hume, D. P. Furkert and M. A. Brimble,
Journal of Organic Chemistry, 2014, 79, 5269-5281.

“Synthesis of Truncated Analogues of Preptin-(1-16), and Investigation of Their Ability to Stimulate Osteoblast Proliferation”
R. Kowalczyk, S. H. Yang, M. A. Brimble, K. E. Callon, M. Watson, Y.-E. Park and J. Cornish,
Bioorganic and Medicinal Chemistry, 2014, 22, 3565-3572.

“Structure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus Polymerisation”
P. G. Young, T. Proft, P. W. R. Harris, M. A. Brimble and E. N. Baker,
PLOS ONE, 2014, 9, e99135.

“Expedient Synthesis of Peptides Containing N^ε-Carboxymethyllysine”
M. Kamalov, S. Yang, P. W. R. Harris, G. J. S. Cooper and M. A. Brimble,
Synlett, 2014, 25, 1835-1838.

“An Investigation of the Role of the Adiponectin Variable Domain on the Stability of the Collagen-like Domain”
P. W. R. Harris, L. Hampe, M. Radjainia, M. A. Brimble and A. Mitra,
Biopolymers (Peptide Science), 2014, 101, 313-321.

“Synthesis and Biological Evaluation of the Osteoblast Proliferating Cyclic Peptides Dianthins G and H”
H. Kaur, A. M. Heapy, R. Kowalzcyk, Z. Amso, M. Watson, J. Cornish and M. A. Brimble,
Tetrahedron, 2014, 70, 7788-7794.

Invited article for special issue on peptide macrocycles

“Site-Specific Cross-linking of Collagen Peptides by Lysyl Advanced Glycation Endproducts”
M. Kamalov, P. W. R. Harris, G. J. S. Cooper and M. A. Brimble,
Chemical Communications, 2014, 50, 4944-4946.

“One-Pot Synthesis of Functionalized Noble Metal Nanoparticles Using a Rationally Designed Phosphopeptide”
S. Papst, M. A. Brimble, R. D. Tilley, D. E. Williams,
Particle and Particle Systems Characterization, 2014, 31, 971-975.

“Synthesis and Methemoglobinemia-inducing Properties of Benzocaine Isosteres Designed as Humane Rodenticides”
D. Conole, T. M. Beck, M. Jay-Smith, M. D. Tingle, C. T. Eason, M. A. Brimbleand D. Rennison,
Bioorganic and Medicinal Chemistry, 2014, 22, 2220-2235.

“Plant Antimicrobial Peptides Snakin-1 and Snakin-2: Chemical Synthesis and Insights into the Disulfide Connectivity”
P. W. R. Harris, S.-H Yang, A. Molina, G. López, M. Middleditch and M. A. Brimble,
Chemistry – A European Journal, 2014, 20, 5102-5110.

“Preparation of Truncated Orf Virus Entry Fusion Complex Proteins by Chemical Synthesis”
H. Yeung, P. W. R. Harris, C. J. Squire, E. N. Baker and M. A. Brimble,
Journal of Peptide Science, 2014, 20, 398-405.

“Synthesis of Highly Substituted Pyranonaphthalene Spiroketals Related to the Griseusins using a Hauser-Kraus Annulation Strategy”
B. J. Naysmith, D. P. Furkert and M. A. Brimble,
Tetrahedron, 2014, 70, 1199-1206.

“A Convenient Method for the Asymmetric Synthesis of Fluorinated alpha-Amino Acids from Alcohols”
F. Drouet, A. F. M. Noisier, C. S. Harris, D. P. Furkert and M. A. Brimble,
European Journal of Organic Chemistry, 2014, 1195-1201.

Selected for front cover

“Synthesis of the 2-Methylene Analogue of the HRV 3C Protease Inhibitor Thysanone (2-Carbathysanone)”
K. Schünemann, D. P. Furkert, E. C. Choi, S. Connelly, J. D. Fraser, J. Sperry and M. A. Brimble,
Organic and Biomolecular Chemistry, 2014, 12, 905-912.

“Total Synthesis of Heronapyrrole C”
X.-B. Ding, D. P. Furkert, R. J. Capon and M. A. Brimble,
Organic Letters, 2014, 16, 378-381.

“Synthesis of the Spiroacetal Core of the Cephalosporolide Family of Natural Products,
O. C. Finch, D. P. Furkert and M. A. Brimble,
Tetrahedron, 2014, 70, 590-596.

“A Maillard Approach to 2-Formylpyrroles: Synthesis of Magnolamide, Lobechine and Funebral”
T.-Z. Yuen, S. E. Eaton, T. M. Woods, D. P. Furkert, K. W. Choi and M. A. Brimble,
European Journal of Organic Chemistry, 2014, 1431-1437.

“Iridium-Catalysed C–H Borylation Facilitates a Total Synthesis of the HRV 3C Protease Inhibitor (±)-Thysanone”
K. Schünemann, D. P. Furkert, S. Connelly, J. D. Fraser, J. Sperry and M. A. Brimble,
Synlett, 2014, 25, 556-558.

“An Important Side Reaction Using the Thiol, 3,6-Dioxa-1,8-octanedithiol (DODT), in 9-Fluorenylmethoxycarbonyl Based Solid Phase Peptide Synthesis”
P. W. R. Harris, R. Kowalczyk, S.-H. Yang, G. M. Williams and M. A. Brimble,
Journal of Peptide Science, 2014, 20, 186-190.

“Synthesis and Biological Evaluation of 7-Deoxy Analogues of the Human Rhinovirus 3C Protease Inhibitor Thysanone”
K. Schünemann, D. P. Furkert, S. Connelly, J. D. Fraser, J. Sperry and M. A. Brimble,
European Journal of Organic Chemistry, 2014, 122-128.

“Synthesis of a Novel Polyaniline Glycopolymer and its Lectin Binding Studies”
C. Wilcox, J. Jin, H. Charville, S. Swift, T. To,  P. A. Kilmartin, C. W. Evans, R. Cooney and M. A. Brimble,
Australian Journal of Chemistry, 2014, 67, 562-569.

“Structure-Activity Relationships of the N-Terminus of Calcitonin Gene-related Peptide: Key Roles of Alanine-5 and Threonine-6 in Receptor Activation”
D. L. Hay, P. W. R. Harris, R. Kowalczyk, M. A. Brimble, D. L. Rathbone, J. Barwell, A. C. Conner and D. R. Poyner,
British Journal of Pharmacology, 2014, 171, 415-426.

“Total Chemical Synthesis of an Orf Virus Protein, ORFV002, an Inhibitor of the Master Gene Regulator NF-kB”
S. J. Son, P. W. R. Harris, C. J. Squire, E. N. Baker and M. A. Brimble,
Biopolymers (Peptide Science), 2014, 102, 137-144.

2013

“Synthesis of an Azido Precursor to (2S,5R)-5-Hydroxylysine Using an Asymmetric Organocatalytic Chlorination/Reduction Sequence”
M. Johannes and M. A. Brimble,
Journal of Organic Chemistry, 2013, 79, 12809-12813.

“Synthesis and Methemoglobinemia-Inducing Properties of Analogues of para-Aminopropiophenone Designed as Humane Rodenticides”
D. Rennison, D. Conole, M. D. Tingle, J. Yang , C. T. Eason and M. A. Brimble,
Bioorganic and Medicinal Chemistry Letters, 2013, 23, 6629-6635.

“Synthesis and Cytotoxicity of Pyranonaphthoquinone Natural Product Analogues Under Bioreductive Conditions”
A. M. Heapy, A. V. Patterson, J.B. Smaill, S. M. F. Jamieson, C. P. Guise, J. Sperry, P. A. Hume, K. Rathwell and M. A. Brimble,
Bioorganic and Medicinal Chemistry, 2013, 21, 7971-7980.

“Synthesis of Leptosin, A Glycoside Isolated from Manuka Honey”
H. R. M. Aitken, M. Johannes, K. M. Loomes and M. A. Brimble,
Tetrahedron Letters, 2013, 54, 6916-6919.

Selected for front cover

“Total Synthesis of Virgatolide B”
P. A. Hume, D. P. Furkert and M. A. Brimble,
Organic Letters, 2013, 15, 4588-4591.

“Synthesis of Benzannulated Spiroacetals using Chiral Gold-Phosphine Complexes and Chiral Anions”
R. Quach, D. P. Furkert and M. A. Brimble,
Tetrahedron Letters, 2013, 54, 5865-5868.

“Direct Peptide Lipidation via Thiol-ene Coupling Enables Rapid Synthesis and Evaluation of Self-adjuvanting Vaccine Candidates”
T. H. Wright, A. E. S. Brooks, A. J. Didsbury, G. M. Williams, P. W. R. Harris, R. P. Dunbar and M. A. Brimble,
Angewandte Chemie International Edition, 2013, 52, 10616-10619.

“Novel Preparation of Chiral alpha-Amino Acids using the Mitsunobu–Tsunoda Reaction”
A. F. M. Noisier, C. S. Harris and M. A. Brimble,
Chemical Communications, 2013, 49, 7744-7746.

“The Synthesis and Lectin-Binding Properties of Novel Mannose-Functionalised Polymers”
H. Charville, J. Jin, C. E. Evans, M. A. Brimble and D. E. Williams,
Royal Society of Chemistry Advances, 2013, 15435-15441.

“An Improved Method for the Synthesis of Lipopeptide TLR2-Agonists Using Click Chemistry”
T. H. Wright, A. E. S. Brooks, A. J. Didsbury, J. D. McIntosh, K. Burkert, H. Yeung, G. M. Williams, P. R. Dunbar and M. A. Brimble,
Synlett, 2013,1835-1841.

“Prodrugs of N-Dicarboximide Derivatives of the Rat Selective Toxicant Norbormide”
D. Rennison, O. Laita D. Conole, M. Jay-Smith, J. Knauf, S. Bova, M. Cavalli, B. Hopkins, D. S. Linthicum and M. A. Brimble,
Bioorganic and Medicinal Chemistry, 2013, 21, 5886-5899.

“Synthesis of the Cysteine Protease Inhibitors CPI-2081a and CPI-2081b Using a Controlled SPPS Byproduct Forming Reaction”
A. M. Heapy, M. Dragunow and M. A. Brimble,
Synlett, 2013, 1818-1824.

“Enantioselective Access to Benzannulated Spiroketals using a Chiral Sulfoxide Auxiliary”
H. R. M. Aitken, D. P. Furkert, J. G. Hubert, J. M. Wood and M. A. Brimble,
Organic and Biomolecular Chemistry, 2013, 11, 5147-5155.

“Chemical Synthesis of a Masked Analogue of the Fish Antifreeze Potentiating Protein (AFPP)”
S.-H. Yang, J. M. Wojnar, P. W. R. Harris, A. L. DeVries, C. W. Evans and M. A. Brimble,
Organic and Biomolecular Chemistry, 2013, 11, 4935-4942.

Open access: http://pubs.rsc.org/en/content/articlelanding/2013/ob/c3ob41066h

Highlighted in Chemistry World and selected for front cover of OBC Featured in chemeurope.com and bionity.com (http://www.chemeurope.com/en/news/144123/; www.bionity.com/en/news/144123/)

“Grafting from Poly(3,4-ethylenedioxythiophene): A Simple Route to Versatile Electrically Addressable Surfaces”
J. Malmström, M. K. Nieuwoudt, L. T. Strover, A. Hackett, O. Laita, M. A. Brimble, D. E. Williams and J. Travas-Sejdic,
Macromolecules, 2013, 46, 4955-4965.

“Structure and Dynamics of Human Nedd4-1 WW3 in Complex with the alphaENaC PY Motif”
R. Bobby, K. Medini, P. Neudecker, T. V. Lee, M. A. Brimble, F. J. McDonald, J. S. Lott and A. J. Dingley,
Biochimica et Biophysica Acta – Proteins and Proteomics, 2013, 1834, 1632-1641.

“Synthesis of Stable Isotope Labelled Monolysyl Advanced Glycation Endproducts”
T. M. Woods, G. J. S. Cooper and M. A. Brimble,
Amino Acids, 2013, 45, 319-325.

“One-Pot Synthesis of Water Soluble Iron Nanoparticles Using Rationally Designed Peptides and Ligand Release”
S. Papst, S. Cheong, M. J. Banholzer, M. A. Brimble, D. E. Williams and R. D. Tilley,
Chemical Communications, 2013, 49, 4540-4542.

“Synthesis of the Griseusin B Framework via a one-pot Annulation-Methylation-Double Deprotectin-Spirocyclisation Sequence”
B. J. Naysmith and M. A. Brimble,
Organic Letters, 2013, 15, 2006-2009.

“Synthesis of the IGF-II-like Hormone Vesiculin using Regioselective Formation of Disulfide Bonds”
G. M. Williams, G. J. S. Cooper, K. Lee, L. Whiting, and M. A. Brimble,
Organic and Biomolecular Chemistry, 2013, 11, 3145-3150.

Open access: http://pubs.rsc.org/en/content/articlelanding/2013/ob/c3ob40322j

“Telomerase Inhibition Studies of Novel Spiroketal-Containing Rubromycin Derivatives”
T.-Y. Yuen, Y.-P. Ng, F. C. F. Ip, J. L.-Y. Chen, D. J. Atkinson, J. Sperry, N. Y. Ip and M. A. Brimble,
Australian Journal of Chemistry, 2013, 66, 530-533.

“Total Synthesis of Chaetoquadrins H and I”
U. B. Kim, A. F. Dalebrook, D. P. Furkert and M. A. Brimble,
Synlett, 2013, 723-726.

“A Comparison of Boc and Fmoc SPPS Strategies for the Preparation of C-Terminal Peptide alpha-Thiolesters: NY-ESO-1 ³⁹Cys-⁶⁸Ala-COSR”
P. W. R. Harris and M. A. Brimble,
Biopolymers (Peptide Science), 2013,100, 356-365.

“Synthesis of a 6,6-Spiroketal Amino Acid and its Incorporation into a Peptide Turn Sequence using Solid Phase Peptide Synthesis”
J. T. B. Kueh, K. W. Choi, G. M. Williams, K. Moehle, B. Bacsa, J. A. Robinson and M. A. Brimble,
Chemistry – A European Journal, 2013, 19, 3807-3811.

“Identification of Key Residues Involved in Adrenomedullin Binding to the AM₁Receptor”
H. A. Watkins, M. Au, R. Bobby, J. K. Archibold, N. Abdul-Manan, J. M. Moore, M. J.  Middleditch, G. M. Williams, M. A. Brimble, A. J. Dingley and D. L. Hay,
British Journal of Pharmacology, 2013, 169, 143-155.

“Total Synthesis of Chaetoquadrins A-C”
U. B. Kim, D. P. Furkert and M. A. Brimble,
Organic Letters, 2013, 15, 658-661.

“A New Precursor for Conducting Polymer-based Brush Interfaces with Electroactivity in Aqueous Solution”
L. T. Strover, J. Malmström, O. Laita, J. Reynisson, N. Aydemir,  M. K. Nieuwoudt, D. E. Williams, P. R. Dunbar, M. A. Brimble and J. Travas-Sejdic,
Polymer, 2013, 54, 1305-1317.

“DNA Adduct Formation of Mitomycin C. A Test Case for DFT Calculations on Model Systems”
P. Hume, M. A. Brimble and J. Reynisson,
Computational and Theoretical Chemistry, 2013, 1005, 9-15.

“Synthesis and Self-Assembly of a Peptide-Amphiphile as a Drug Delivery Vehicle”
S. J. Soo, M. A. Brimble, S. Yang, P. W. R. Harris, T. Reddingius, B. W. Muir, O. E. Hutt, L. Waddington, J. Guan, and G. P. Savage,
Australian Journal of Chemistry, 2013, 66, 23-29.

Selected for front cover

“Natural Product-Inspired Pyranonaphthoquinone Inhibitors of Indoleamine 2,3-Dioxygenase (IDO-1)”
D. J. A. Bridewell, J. Sperry, J. R. Smith, P. Kosim-Satyaputra, L.-M. Ching, J. F. Jamie and M. A. Brimble,
Australian Journal of Chemistry, 2013, 66, 40-49.

“A Single Pseudoproline and Microwave Solid Phase Peptide Synthesis Facilitates an Efficient Synthesis of Human Amylin 1-37″
P. W. R. Harris, R. Kowalczyk, D. Hay and M. A. Brimble,
International Journal of Peptide Research and Therapeutics, 2013, 19, 147-155.

“Determination of pKa and Forced Degradation of the Indoloquinoline Antimalarial Compound Cryptolepine Hydrochloride”
N. Kuntworbe, R. G. Alany, M. A. Brimble and R. Al-Kassas,
Pharmaceutical Development and Technology, 2013, 18, 866-876.

2012

“Synthesis and Recycling of Antifreeze Glycoproteins in Polar Fishes”
C. W. Evans, L. Hellman, M. Middleditch, J. M. Wojnar, M. A. Brimble and A. L. DeVries,
Antarctic Science, 2012, 24, 259-268.

“The Chemical Synthesis of the Collagenous Domain of the Hormone Adiponectin”
P. W. H. Harris and M. A. Brimble,
International Journal of Peptide Research and Therapeutics, 2012, 18, 63-70.

“Total Synthesis of Danshenspiroketallactone”
D. F. Chorley, J. L.-Y. Chen, D. P. Furkert, J. Sperry and M. A. Brimble,
Synlett, 2012, 23, 128-130.

“Formal Synthesis of Berkelic Acid: A Lesson in alpha-Alkylation Chemistry”
M. McLeod, Z. Wilson and M. A. Brimble,
Journal of Organic Chemistry, 2012, 77, 400-406.

“Synthesis of the Antifungal Cyclic Peptides Tunicyclins C and D”
H. Kaur, A. M. Heapy and M. A. Brimble,
Synlett, 2012, 23, 275-277.

“Enantioselective Synthesis of C-Linked Spiroacetal-Triazoles as Privileged Natural Product-like Scaffolds”
J. T. B. Kueh, K. W. Choi and M. A. Brimble,
Organic and Biomolecular Chemistry, 2012, 10, 5993-6002.

Invited paper for special issue to celebrate 10th anniversary of OBC

“An Efficient Synthesis of 3-Alkyl-1,5,3-dioxazepanes and Their Use as Electrophiles in Double Mannich Reactions”
K. Sparrow, D. Barker and M. A. Brimble,
Tetrahedron, 2012, 68, 1017-1028.

“Metabolic and Behavioural Adaptions During Early Development of the Antartic Silverfish, Pleuragramma Antarcticum”
C. Evans, D. E. Williams, M. Vacchi, M. A. Brimble and A. L. DeVries,
Polar Biology, 2012, 35, 891-898.

“Synthesis of a Dicarba Analogue of Human beta-Defensin-1 using a Combined Ring Closing Metathesis-Native Chemical Ligation Strategy”
A. M. Heapy, G. M. Williams, J. D. Fraser and M. A. Brimble,
Organic Letters, 2012, 14, 878-881.

“Synthesis and anti-Helicobacter pylori Activity of Analogues of Spirolaxine Methyl Ether”
I. Dimitrov, D. P. Furkert, J. D. Fraser, F. J. Radcliff, O. Finch and M. A. Brimble,
MedChemComm, 2012, 3, 944-949.

Invited paper for special issue on natural products and selected for front cover

“A Convergent Synthesis of the 2-Formylpyrrole Spiroketal Natural Product Acortatarin A”
H. M. Geng, J. L.-Y. Chen, D. P. Furkert, S. Jiang and M. A. Brimble,
Synlett, 2012, 23, 855-858.

“The Bioreductive Alkylation of DNA by Kalafungin. A Theoretical Investigation”
P. Hume, J. Reynisson and M. A. Brimble,
Australian Journal of Chemistry, 2012, 65, 402-408.

“Synthesis and Evaluation of Disulfide Bond Mimetics of Amylin-(1-8) as Agents to Treat Osteoporosis”
R. Kowalczyk, P. W. R. Harris, M. A. Brimble, K. E. Callon, M. Watson and J. Cornish,
Bioorganic and Medicinal Chemistry, 2012, 20, 2661-2668.

“Tyrosine Modified Analogues of the alpha4 beta7 Integrin Inhibitor Biotin-R₈ERY Prepared via Click Chemistry: Synthesis and Biological Evaluation”
S. Papst, A. Noisier, M. A. Brimble, Y. Yang and G. W. Krissansen,
Bioorganic and Medicinal Chemistry, 2012, 20, 2638-2644.

Selected for inclusion on Global Medical Discovery website http://globalmedicaldiscovery.com

“A Method for the Generation of Pam₂Cys-Based Lipopeptide Mimics via CuAAC Click Chemistry”
H. Yeung, D. J. Lee, G. M. Williams, P. W. R. Harris and M. A. Brimble,
Synlett, 2012, 23, 1617-1620.

“A Highly Conserved Tryptophan in the N-Terminal Variable Domain Regulates Rate of Disulfide Bond Formation and Oligomeric Assembly of Adiponectin”
M. Radjainia, B. Huang, B. Bai, M. Schmitz, S. H. Yang, P. W. R. Harris, M. D. W. Griffin, M. A. Brimble, Y. Wang, and A. K. Mitra,
FEBS Journal, 2012, 279, 2495-2507.

“Novel Phosphopeptides as Surface-Active Agents in Iron Nanoparticle Synthesis”
R. Peltier, W. R. Siah, G. V. M. Williams, M. A. Brimble, R. D. Tilley and D. E. Williams,
Australian Journal of Chemistry, 2012, 65, 680-685.

“Regioselective Iridium(I)-Catalysed Remote Borylation of Oxygenated Naphthalenes”
P. Hume, D. P. Furkert and M. A. Brimble,
Tetrahedron Letters, 2012, 53, 3771-3773.

“Synthesis of 2-Alkyl chromanones via a Conjugate Addition Approach”
L. A. Stubbing, F. F. Li, D. P. Furkert, V. E. Caprio and M. A. Brimble,
Tetrahedron, 2012, 68, 6948-6956.

“Design and Synthesis of Prodrugs of the Rat Selective Toxicant Norbormide”
D. Rennison, O. Laita, S. Bova, M. Cavalli, B. Hopkins, D. S. Linthicum and M. A. Brimble,
Bioorganic and Medicinal Chemistry, 2012, 20, 3997-4011.

“A Tandem Diels-Alder/Mannich Approach to the Synthesis of AE and ABE Ring Analogues of Delphinium Alkaloids”
K. J. Goodall, M. A. Brimble and D. Barker,
Tetrahedron, 2012, 68, 5759-5778.

“A Simple Solid Phase, Peptide-Based Fluorescent Assay for the Efficient and Universal Screening of HRV 3C Protease Inhibitors”
K. Schünemann, S. Connelly, R. Kowalczyk, J. Sperry, I. A. Wilson, J. D. Fraser and M. A. Brimble,
Bioorganic and Medicinal Chemistry Letters, 2012, 22, 5018-5024.

“Synthesis of the All-L Cyclopeptides Versicoloritides A, B and C”
H. Kaur, A. M. Heapy and M. A. Brimble,
Synlett, 2012, 23, 2284-2288.

“Synthesis and Biological Evaluation of Tyrosine Modified Analogues of the alpha4 beta7 Integrin Inhibitor Biotin-R₈ERY”
S. Papst, A. F. M. Noisier, M. A. Brimble, Y. Yang and G. W. Krissansen,
Bioorganic and Medicinal Chemistry, 2012, 20, 5139-5149.

“Synthesis and SAR of a Library of Cell-Permeable Biotin-R₈ERY* Peptidomimetics Inhibiting alpha4 beta7 Integrin Mediated Adhesion of TK-1 Cells to MAdCAM-1-Fc”
S. Papst, A. F. M. Noisier, M. A. Brimble, Y. Yang, Y.-C. Chan and G. W. Krissansen,
Australian Journal of Chemistry, 2012, 65, 1349-1358.

“A Slow Gradient Approach for the Purification of Synthetic Polypeptides by Reversed Phase High Performance Liquid Chromatography”
P. W. R. Harris, D. J. Lee and M. A. Brimble,
Journal of Peptide Science, 2012, 18, 549-555.

“Synthesis of Multivalent Neoglycoconjugates of MUC1 by the Conjugation of Carbohydrate-centred, Triazole-Linked Glycoclusters to MUC1 peptides using Click Chemistry”
D. J. Lee, S.-H. Yang, G. M. Williams and M. A. Brimble,
Journal of Organic Chemistry, 2012, 77, 7564-7571.

“How to Blast Osteoblasts? Novel Dicarba Analogues of Amylin-(1-8) to Treat Osteoporosis”
R. Kowalczyk, M. A. Brimble, K. E. Callon, M. Watson and J. Cornish,
Bioorganic and Medicinal Chemistry, 2012, 20, 6011-6018.

Highlighted in World Biomedical Frontiers<http://biomedfrontiers.org/ [ISSN: 2328-0166]

“Total Synthesis of 7′,8′-Dihydroaigialospirol”
T. Y. Yuen and M. A. Brimble,
Organic Letters, 2012, 14, 5154-5157.

“Total Synthesis of the Initially Reported and Revised Structures of the Neuroprotective Agent Palmyrolide A”
A. D. Wadsworth, D. P. Furkert, J. Sperry and M. A. Brimble,
Organic Letters, 2012, 14, 5374-5377.

“Synthesis of Monolysyl Advanced Glycation Endproducts and Their Incorporation into Collagen Model Peptides”
T. Woods, M. Kamalov, P. W. R. Harris, G. J. S. Cooper and M. A. Brimble,
Organic Letters, 2012, 14, 5740-5743.

“Synthesis of the Peptaibol Framework of the Anticancer Agent Culicinin D: Stereochemical Assignment of the AHMOD Moiety”
K.-Y. Hung, P. W. R. Harris and M. A. Brimble,
Organic Letters, 2012, 14, 5784-5787.

“Synthesis of the Tetracyclic Core of Berkelic Acid using Gold(I)-Catalyzed Hydroarylation and Oxidative Radical Cyclizations”
M. A. Brimble, I. Haym, J. Sperry and D. P. Furkert,
Organic Letters, 2012, 14, 5820-5823.

2011

“How do Antarctic Notothenioid Fishes Cope with Internal ice? A Novel Function for Antifreeze Glycoproteins”
C. W. Evans, V. Gubala, R. Nooney, D. E. Williams, M. A. Brimble and A. L. De Vries,
Antarctic Science, 2011, 23, 57-64.

“Synthesis of Benzotriazole Analogues of the Helicobactericidal Agents CJ-13,015, CJ-13,102, CJ-13,108 and CJ-13,104 using a Regioselective 1,3-Dipolar Cycloaddition”
D. J. Atkinson, J. Sperry and M. A. Brimble,
Synlett, 2011, 99-103.

“A Convergent Synthesis of the [4.4]-Spiroacetal-gamma-lactones Cephalosporolides E and F”
M. A. Brimble, O. C. Finch, A. M. Heapy, J. D. Fraser, D. P. Furkert and P. D. O’Connor,
Tetrahedron, 2011, 67, 995-1001.

“Synthesis and Assignment of Stereochemistry of the Antibacterial Cyclic Peptide Xenamatide”
K.-Y. Hung, P. W. R. Harris, A. M. Heapy and M. A. Brimble,
Organic and Biomolecular Chemistry, 2011, 9, 236-242.

“Synthesis of MUC1 Neoglycopeptides using Efficient Microwave-Enhanced Chaotrope-Assisted Click Chemistry”
D. J. Lee, P. W. R. Harris and M. A. Brimble,
Organic and Biomolecular Chemistry, 2011, 9, 1621-1626.

“Synthesis of an Isotopically-Labelled Antarctic Fish Antifreeze Glycoprotein Probe”
J. M. Wojnar, C. W. Evans, A. L. DeVries and M. A. Brimble,
Australian Journal of Chemistry, 2011, 723-731.

Invited paper for special issue on women in science to celebrate International Year of Chemistry and 100th anniversary of Nobel prize being awarded to Marie Curie

“Synthesis of Benzannulated Spiroketals using an Oxidative Radical Cyclization”
J. Sperry, Y.-C. Liu, Z. E. Wilson, J. G. Hubert and M. A. Brimble,
Synthesis, 2011, 1383-1398.

“Efficient Synthesis of the Spiroacetal Core of Paecilospirone via Oxidative Radical Cyclisation ”
M. Jay-Smith, D. P. Furkert, J. Sperry and M. A. Brimble,
Synlett, 2011, 1395-1398.

“A Flexible Approach to 6,5-Benzannulated Spiroketals”
Z. E. Wilson, J. G. Hubert and M. A. Brimble,
European Journal of Organic Chemistry, 2011, 28, 3938-3945.

Invited paper for special issue to celebrate International Year of Chemistry

“Enantioselective Synthesis of Pyranonaphthoquinone Antibiotics using a CBS Reduction/Cross-Metathesis/oxa-Michael Strategy”
P. A. Hume, J. Sperry and M. A. Brimble,
Organic and Biomolecular Chemistry, 2011, 9, 5423-5430.

“Total Synthesis of Paecilospirone”
T.-Y. Yuen  S.-H. Yang and M. A. Brimble,
Angewandte Chemie International Edition, 2011, 50, 8350-8353.

“Gold(I)-Catalysed Intramolecular Hydroamination of alpha-Quaternary Alkynes: Synthetic Studies Towards Spiroimine Marine Toxins”
Y. C. Zhang, D. P. Furkert, S. Gueret, F. Lombard and M. A. Brimble,
Tetrahedron Letters, 2011, 4896-4898.

“The Enantioselective Synthesis of Tetracyclic Methyllycaconitine Analogues”
K. Sparrow, D. Barker and M. A. Brimble,
Tetrahedron, 2011, 67, 7989-7999.

“The Translocator Protein (Peripheral Benzodiazepine Receptor) Mediates Rat-selective Activation of the Mitochondrial Permeability Transition by Norbormide”
A. Zulian, J. Šileikytė, V. Petronilli, S. Bova, F. Dabbeni-Sala, G. Cargnelli, D. Rennison, M. A. Brimble, B. Hopkins, P. Bernardi and F. Ricchelli,
Biochimica et Biophysica Acta – Bioenergetics, 2011, 1807, 1600-1605.

“An Improved Procedure for the Preparation of Aminomethyl Polystyrene Resin and its Use in Solid Phase (Peptide) Synthesis”
P. W. R. Harris, S.-H. Yang and M. A. Brimble,
Tetrahedron Letters, 2011, 52, 6024-6026.

“An Enantioselective Formal Synthesis of Berkelic Acid”
M. C. McLeod, Z. E. Wilson and M. A. Brimble,
Organic Letters, 2011, 13, 5382-5385.

“Synthesis of a NDPK Phosphocarrier Domain Peptide Containing a Triazolylalanine Analogue of Phosphohistidine Using Click Chemistry”
S.-H. Yang, D.-J. Lee and M. A. Brimble,
Organic Letters, 2011, 13, 5604-5607.

“Synthesis of the Bis-Spiroacetal Core of the Antimitotic Agent Spirastrellolide B”
J. L.-Y. Chen and M. A. Brimble,
Journal of Organic Chemistry, 2011, 76, 9417-9428.

2010

“Towards the Total Chemical Synthesis of the Cancer Protein NY-ESO-1”
P. W. R. Harris and M. A. Brimble,
Biopolymers (Peptide Science), 2010, 94, 542-550.

Invited paper for special issue of peptide science dedicated to Professor Steve Kent

“Microwave-Assisted Synthesis of Fluorescein-Labelled GalNAc alpha 1-O-Ser/Thr (Tn) Glycopeptides as Immunological Probes”
D. J. Lee, P. W. R. Harris, R. Kowalczyk, P. R. Dunbar and M. A. Brimble,
Synthesis, 2010, 763-769.

“Improved Synthesis of the Benzyne Precursor 2-(Trimethylsilyl)phenyl Trifluoromethanesulfonate”
D. P. Atkinson, J. Sperry and M. A. Brimble,
Synthesis, 2010, 911-913.

“Metal Binding Studies Using Spiroacetal Crown Ethers”
M. Nikac, M. A. Brimble, R. L. Crumbie and T. D. Bailey,
Tetrahedron Letters, 2010, 51, 1072-1074.

“Total Synthesis and Absolute Configuration of (–)-Berkeleyamide A”
J. Sperry, E. B. J. Harris and M. A. Brimble,
Organic Letters, 2010, 12, 420-423.

“A Flexible Asymmetric Synthesis of the Tetracyclic Core of Berkelic Acid Using a Horner-Wadsworth-Emmons/oxa-Michael Cascade”
Z. E. Wilson and M. A. Brimble,
Organic and Biomolecular Chemistry, 2010, 8, 1284-1286.

“Synthesis of Triazole Analogues of the Nanaomycin Antibiotics using ‘Click Chemistry’ ”
K. Rathwell, J. Sperry and M. A. Brimble,
Tetrahedron, 2010, 66, 4002-4009.

“Synthesis of the Bis-Spiroacetal C25–C40 Moiety of the Antimitotic Agent Apirastrellolide B using a Bis-Dithiane Deprotection/Spiroacetalisation Sequence”
J. L.-Y. Chen and M. A. Brimble,
Chemical Communications, 2010, 46, 3967-3969.

“Synthesis of the FG Ring Fragment of Pectenotoxins 1-9”
A. Heapy and M. A. Brimble,
Tetrahedron, 2010, 66, 5424-5431.

“Synthesis of the Pyranonaphthoquinones Dehydroherbarin, (+)-Astropaquinone B and (+)-Astropaquinone C en route to Ascomycones A and B”
A. Wadsworth, J. Sperry and M. A. Brimble,
Synthesis, 2010, 2604-2608.

“Growth Habit Modification of Ice Crystals using Antifreeze Glycoprotein (AFGP) Analogues”
R. Peltier, C. W. Evans, A. L. DeVries, M. A. Brimble, A. J. Dingley and D. E. Williams,
Crystal Growth and Design, 2010, 10, 5066–5077.

“A Double Mannich Approach to the Synthesis of Substituted Piperidones – Application to the Synthesis of Substituted E-ring Analogues of Methyllycaconitine”
Y. Chan, J. Balle, J. K. Sparrow, P. D. W. Boyd, M. A. Brimble and D. Barker,
Tetrahedron, 2010, 66, 7179-7191.

“Hetero-Directed Reverse Wacker Oxidations. Synthesis of the Reported Structure of (–)-Herbaric Acid”
P. J. Choi, J. Sperry and M. A. Brimble,
Journal of Organic Chemistry, 2010, 75, 7388-7392.

“Stereoselective Synthesis of 4-Substituted 4-Hydroxypiperidines via Epoxidation-Ring Opening of 4-Methylenepiperidines”
V. A. McKay, S. J. Thompson, P. M. Tran, K. J. Goodall, M. A. Brimble and D. Barker,
Synlett, 2010, 2631-2635.

“Synthesis of a Functionalised 7,6-Bicyclic Spiroimine Ring Fragment of the Spirolides”
S. M. Guéret, D. P. Furkert and M. A. Brimble,
Organic Letters, 2010, 12, 5226-5229.

“Synthesis of Methyl N-Boc-(2S,4R)-4-Methylpipecolate”
K.-Y. Hung, P. W. R. Harris and M. A. Brimble,
Journal of Organic Chemistry, 2010, 75, 8728-8731.

“Synthesis and Antifreeze Activity of Fish Antifreeze Glycoproteins and Their Analogues”
R. Peltier, M. A. Brimble, J. M. Wojnar, D. E. Williams, C. W. Evans and A. L. DeVries,
Chemical Science, 2010, 1, 538-551.

Open Access: http://pubs.rsc.org/en/Content/ArticleLanding/2010/SC/c0sc00194e

Invited review for inaugural issue

2009

“NNZ-2566: A Gly–Pro–Glu Analogue With Neuroprotective Efficacy in a Rat Model of Acute Focal Stroke”
M. J. Bickerdike, G. B. Thomas, D. C. Batchelor, E. S. Sirmianne, W. Leong, H. Lin, F. Sieg, J. Wen, M. A. Brimble, P. W. Harris and P. D. Gluckman,
Journal of the Neurological Sciences, 2009, 278, 85-90.

“In vitro Metabolism of Norbormide in Rat, Mouse and Guinea Pig Liver Preparations”
S. Ravindran, B. Hopkins, S. Bova, D. Rennison, M. A. Brimble and M. Tingle,
Environmental Toxicology and Pharmacology, 2009, 27, 144-148.

“A Novel Approach to the CDE Ring System of Pectenotoxin-4 Triggered by VO(acac)₂ Induced Epoxy-Acetalization”
S. Carley and M. A. Brimble,
Organic Letters, 2009, 11, 563-566.

“Synthesis of Spiroacetal-Nucleosides as Privileged Natural Product-like Scaffolds”
K. W. Choi and M. A. Brimble,
Organic and Biomolecular Chemistry, 2009, 7, 1424-1436.

“Synthesis of Enantiopure Bicyclic alpha,alpha-Disubstituted Spirolactams via Asymmetric Birch Reductive Alkylation”
S. M. Guéret, P. D. O’Connor and M. A. Brimble,
Organic Letters, 2009, 11, 963-966.

“A Facile Cross-Metathesis–Radical-Cyclisation Approach to Monobenzannulated Spiroketals”
Y.-C. Liu, J. Sperry, D. C. K. Rathwell and M. A. Brimble,
Synlett, 2009, 793-797.

“Synthesis of 6,6-Bisbenzannulated Spiroketals Related to the Rubromycins Using a Double Intramolecular Hetero-Michael Addition (DIHMA)”
P. Choi, D. C. K. Rathwell and M. A. Brimble,
Tetrahedron Letters, 2009, 50, 3245-3248.

Invited article for the special edition to mark the 50th golden anniversary of Tetrahedron Letters

“Synthesis of AE and BE Ring Analogues of the Alkaloid Methyllycaconitine”
H. Guthmann, D. Conole, E. Wright, K. Koerber, D. Barker and M. A. Brimble,
European Journal of Organic Chemistry, 2009, 1944-1960.

“Use of Click Chemistry for the Synthesis of Tetrazole-Containing Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)”
K.-Y. Hung, P. W. R. Harris and M. A. Brimble,
Synlett, 2009, 1233-1236.

“Synthetic Studies Towards the Anti-inflammatory Agent, Oleocanthal using a Johnson–Claisen (Orthoester) Rearrangement Strategy”
J. T. B. Kueh, P. D. O’Connor, H. Hügel and M. A. Brimble,
Archive for Organic Chemistry (ARKIVOC), 2009, (vii), 58-71.

“Stability of 5(6)-Carboxyfluorescein in Microwave-Assisted Synthesis of Fluorescein-Labelled O-Dimannosylated Peptides”
R. Kowalczyk, P. W. R. Harris, R. P. Dunbar and M. A. Brimble,
Synthesis, 2009, 2210-2222.

“Influence of alpha-Methyl Substitution of Proline-based Organocatalysts on the Asymmetric alpha-Oxidation of Aldehydes”
S. -T. Tong, M. A. Brimble and D. Barker,
Tetrahedron, 2009, 65, 4801-4807.

“Enantioselective Synthesis of the 3C-Protease Inhibitor (–)-Thysanone using a Staunton-Weinreb Annulation Strategy”
J. Sperry, T. Y. Yuen and M. A. Brimble,
Synthesis, 2009, 2561-2569.

Biomimetic Studies Towards the Cardinalins: Synthesis of (+)-Ventiloquinone L and an Unusual Dimerisation”
J. Sperry, J. J. P. Sejberg, F. M. Stiemke and M. A. Brimble,
Organic and Biomolecular Chemistry, 2009, 7, 2599-2603.

“Synthesis of Fish Antifreeze Neoglycopeptides Using Microwave-assisted ‘Click Chemistry’”
N. Miller, G. M. Williams and M. A. Brimble,
Organic letters, 2009, 11, 2409-2412.

“Synthesis of (±)-Wine Lactone and Its Analogues by a Diels–Alder Approach”
P. D. O’Connor, U. B. Kim and M. A. Brimble,
European Journal of Organic Chemistry, 2009, 4405-4411.

Selected for front cover

“A Novel Approach to Monobenzannulated Spiroketals Using Styrene in the Kulinkovich Reaction”
I. Haym and M. A. Brimble,
Synlett, 2009, 2315-2319.

“Synthesis of an Arginine Tagged [Cys¹⁵⁵-Arg¹⁸⁰] Fragment of NY-ESO-1: Elimination of an Undesired By-product using ‘In House’ Resins”
P. W. R. Harris and M. A. Brimble,
Synthesis, 2009, 3460-3466.

“An Efficient Formal Synthesis of the Human Telomerase Inhibitor (±)-gamma-Rubromycin”
D. C. K. Rathwell, S. -H. Yang, K. Y. Tsang and M. A. Brimble,
Angewandte Chemie International Edition, 2009, 7996-8000.

Selected for front cover and selected as a very important paper (VIP) -only 5% of papers selected as VIP papers

“Pyranonaphthoquinone Derivatives of Eleutherin, Ventiloquinone L, Thysanone and Nanaomycin A Possessing a Diverse Topoisomerase II Inhibition and Cytotoxicity Spectrum”
J. Sperry, I. Loreno-Castrillejo, M. A. Brimble and F. Machin,
Bioorganic and Medicinal Chemistry, 2009, 17, 7131-7137.

“Synthesis and Reactivity of beta-Methoxymethyl Enecarbamates”
P. D. O’Connor, M. G. Marino, S. M. Guéret and M. A. Brimble,
Journal of Organic Chemistry, 2009, 74, 8893-8896.

“A One-pot Approach to Neoglycopeptides Using Orthogonal Native Chemical Ligation and Click Chemistry”
D. J. Lee, K. Mandal, P. W. R. Harris, M. A. Brimble and S. B. H. Kent,
Organic Letters, 2009, 11, 5270-5273.

2008

“Use of (S)-5-(2-Methylpyrrolidin-2-yl)-1H-tetrazole as a Novel and Enantioselective Organocatalyst for the Aldol Reaction”
S.-T. Tong, P. W. R. Harris, D. Barker and M. A. Brimble,
European Journal of Organic Chemistry, 2008, 164-170.

“Synthesis of Fluorescein-Labelled O-Mannosylated Peptides as Components for Synthetic Vaccines: Comparison of Two Synthetic Strategies”
M. A. Brimble, R. Kowalczyk, P. W. R. Harris, P. R. Dunbar and V. J. Muir,
Organic and Biomolecular Chemistry, 2008 6, 112-121.

“Chemoenzymatic Synthesis of Deoxy Analogues of the DNA Topoisomerase II Inhibitor Eleutherin and the 3C-Protease Inhibitor Thysanone”
P. Bachu, J. Sperry and M. A. Brimble,
Tetrahedron, 2008, 64, 4827-4834.

Invited article for Tetrahedron symposia-in-print – “Natural Products Synthesis”

“Synthesis of a C8 Oxygenated Pyranonaphthoquinone: A Useful Precursor to Dimeric Pyranonaphthoquinones”
P. Bachu, M. A. Brimble and J. Sperry,
Tetrahedron, 2008, 64, 3343-3350.

“An Approach to an Enantioselective Synthesis of Crisamicin A via a Novel Double Hauser-Kraus Annulation Strategy”
O. Andrey, J. Sperry, U. S. Larsen and M. A. Brimble,
Tetrahedron, 2008, 64, 3912-3927.

“¹H and ¹³C NMR Spectra for C-6 and C-9 Substituted 3-Azabicyclo[3.3.1]nonanes”
K. J. Goodall, M. A. Brimble and D. Barker,
Magnetic Resonance in Chemistry, 2008, 46, 75-79.

“A Facile Enantioselective Synthesis of the Dimeric Pyranonaphthoquinone Core of the Cardinalins”
M. A. Brimble, J. S. Gibson, J. J. P. Sejberg and J. Sperry,
Synlett, 2008, 867-870.

“Novel Use of N-Carboalkoxy alpha,beta-Unsaturated Iminium Ions as Dienophiles in Diels-Alder Reactions”
P. D. O’Connor, K. Koerber and M. A. Brimble,
Synlett, 2008, 1036-1038.

“Anti-Helicobacter pylori Activity of Derivatives of the Phthalide-Containing Antibacterial Agents Spirolaxane Methyl Ether, CJ-12,954, CJ-13,013, CJ-13,102, CJ-13,104, CJ-13,108 and CJ-13,015”
F. J. Radcliff, J. D. Fraser, Z. E. Wilson, A. M. Heapy, J. E. Robinson, C. J. Bryant, C. L. Flowers and M. A. Brimble,
Bioorganic and Medicinal Chemistry, 2008, 16, 6179-6185.

“Buchwald-Hartwig Mono-N-arylation of 2,6-Dihaloisonicotinic Acid Derivatives: A Convenient Desymmetrization Method”
A. V. Lorimer, P. D. O’Connor and M. A. Brimble,
Synthesis, 2008, 2764-2770.

“An Efficient Enantioselective Synthesis of the 3C Protease Inhibitor (–)-Thysanone”
J. Sperry and M. A. Brimble,
Synlett, 2008, 1910-1912.

“Synthesis of Spiroacetal-Triazoles as Privileged Natural Product-Like Scaffolds Using ‘Click Chemistry’”
K. W. Choi and M. A. Brimble,
Organic and Biomolecular Chemistry, 2008, 6, 3518-3526.

Selected for front cover and invited paper for special issue to honour Professor Andrew Holmes’s 65th birthday

“A Facile Synthesis of a Spironitrone and a Study of its Cycloaddition and Nucleophilic Addition Reactions”
D. Crimmins, I. Dimitrov, P. D. O’Connor, V. Caprio and M. A. Brimble,
Synthesis, 2008, 3319-3325.

“The Synthesis of Phosphopeptides Using Microwave-assisted Solid Phase Peptide Synthesis”
P. W. R. Harris, G. M. Williams, P. Shepherd and M. A. Brimble,
International Journal of Peptide Research and Therapeutics, 2008, 14, 387-392.

“Diastereoselective Synthesis of Substituted 4-Piperidones and 4-Piperidols Using a Double Mannich Reaction”
Y. Chan, H. Guthmann, M. A. Brimble and D. Barker,
Synlett, 2008, 2601-2604.

“Enantioselective Synthesis of the Dimeric Pyranonaphthoquinone Core of the Cardinalins Using a Late-Stage Homocoupling Strategy”
J. Sperry, J. S. Gibson, J. J. P. Sejberg and M. A. Brimble,
Organic and Biomolecular Chemistry, 2008, 6, 4261-4270.

2007

“Synthesis of a Regioisomeric Analogue of the 3C-Protease Inhibitor Thysanone via a Hauser Annulation Strategy”
M. A. Brimble, S. I. Houghton and P. D. Woodgate,
Tetrahedron, 2007, 63, 880-887.

“A Facile Synthesis of 1,1’-Spirobi(3H,3’H)isobenzofurans”
M. A. Brimble and C. V. Burgess,
Synthesis, 2007, 754-760.

“Synthesis of a C-Terminal Thioester Derivative of the Lipopeptide Pam₂CSKKKKG Using Fmoc SPPS”
P. W. R. Harris, M. A. Brimble, R. Dunbar and S. B. H. Kent,
Synlett, 2007, 713-716.

Synthesis of Isotopically Labelled Thiol Volatiles and Cysteine Conjugates for Quantification of Sauvignon Blanc Wine”
K. R. Hebditch, L. Nicolau and M. A. Brimble,
Journal of Labelled Compounds and Radiopharmaceuticals, 2007, 50, 237-243.

“Synthesis of Thiacrown and Azacrown Ethers Based on a Spiroacetal Framework”
M. A. Brimble, M. Nikac and R. Crumbie,
Tetrahedron, 2007, 63, 5220-5226.

“Synthesis and Activity Studies of Analogues of the Rat Selective Toxicant Norbormide”
D. Rennison, S. Bova, M. Cavalli, F. Ricchelli, A. Zulian, B. Hopkins and M. A. Brimble,
Bioorganic and Medicinal Chemistry, 2007, 15, 2963-2974.

“A Facile Synthesis of Aryl Spirodioxines Based on a 3H,3’H-2,2’-Spirobi(benzo[b][1,4]dioxane) Skeleton”
M. A. Brimble, Y.-C. Liu and M. Trzoss,
Synthesis, 2007, 1392-1402.

“Synthesis of Indole Analogues of the anti-Helicobacter pylori Compounds CJ-13,015, CJ-13,102, CJ-13,104 and CJ-13,108”
Z. E. Wilson, A. M. Heapy and M. A. Brimble,
Tetrahedron, 2007, 63, 5379-5385.

“Synthesis of Aromatic Spiroacetals Related to gamma-Rubromycin Based on a 3H-Spiro[1-benzofuran-2,2’-chromane] Skeleton”
K. Y. Tsang and M. A. Brimble,
Tetrahedron, 2007, 63, 6015-6034.

Invited paper for special 50th anniversary issue of Tetrahedron

“Assessing the Molecular Basis for Rat-Selective Induction of the Mitochondrial Permeability Transition by Norbormide”
A. Zulian, V. Petronilli, S. Bova, F. Dabbeni-Sala, G. Cargnelli, M. Cavalli, D. Rennison, J. Stäb, O. Laita, D. J. Lee,  M. A. Brimble, B. Hopkins, P. Bernardi and F. Ricchelli,
Biochimica et Biophysica Acta, Bioenergetics, 2007, 1767, 980-988.

“¹H and ¹³C NMR Spectra of Methylmaleimido- and Methylsuccinimidoanthranilate Esters of 1-Hydroxymethyl-6-methoxy-3-azabicyclo[3.3.1]nonanes”
K. J. Goodall, M. A. Brimble and D. Barker,
Magnetic Resonance in Chemistry, 2007, 45, 695-699.

“A Short Enantioselective Synthesis of the Topoisomerase II Inhibitor (+)-Eleutherin”
J. S. Gibson, O. Andrey and M. A. Brimble,
Synthesis, 2007, 2611-2613.

“Enantioselective Synthesis of an Analogue of Nanaomycin A”
M. A. Brimble, P. Bachu and J. Sperry,
Synthesis, 2007, 2887-2893.

“Synthesis of the anti-Helicobacter pylori Agent (+)-Spirolaxine Methyl Ether and the Unnatural (2”S)-Diastereomer”
J. Robinson and M. A. Brimble,
Organic and Biomolecular Chemistry, 2007, 5, 2572-2582.

“The Influence of Microwave Irradiation on Lipase-Catalyzed Kinetic Resolution of Racemic Secondary Alcohols”
P. Bachu, J. S. Gibson, J. Sperry and M. A. Brimble,
Tetrahedron Asymmetry, 2007, 18, 1618-1624.

“Synthesis of the FG Fragment of the Pectenotoxins”
A. M. Heapy, T. W. Wagner and M. A. Brimble,
Synlett, 2007, 2359-2362.

“Synthesis and Assignment of the Absolute Configuration of the anti-Helicobacter pylori Agents CJ-12,954 and CJ-13,014”
M. A. Brimble and C. J. Bryant,
Organic and Biomolecular Chemistry, 2007, 5, 2858-2866.

“Synthesis of Mannosylated Glycopeptides as Components for Synthetic Vaccines”
R. Kowalczyk, M. A. Brimble and R. Dunbar,
Peptide Science, 2007, 88, 539-539.

Also in “Advances in Experimental Medicine and Biology,” 2009, Vol 611 Peptides for Youth, eds S. Del Valle, E. Escher and R. Dunbar, chapter 155, p 351-352, Springer New York.

“Peripheral Administration of a Novel Diketopiperazine, NNZ 2591, Prevents Brain Injury and Improves Somatosensory-Motor Function Following Hypoxia-ischemia in Adult Rats”
J. Guan, S. Matai, P. W .R. Harris, M. A. Brimble, J.-Y. Wen, R. Zhang and P. D. Gluckman,
Neuropharmacology, 2007, 53, 749-762.

“A Comparative Study of the Different Glycosylation Methods for the Synthesis of D-Mannopyranosides of N–alpha-fluorenylmethoxycarbonyl-trans-4-hydroxy-L-proline Allyl Ester”
D. J. Lee, R. Kowalczyk, V. J. Muir, P. M. Rendle and M. A. Brimble,
Carbohydrate Research, 2007, 342, 2628-2634.

2006

“Methyllycaconitine Analogues have Mixed Antagonist Effects at Nicotinic Acetylcholine Receptors”
D. Barker, D. H.-S. Lin, J. E. Carland, C. P.-Y Chu, M. Chebib, M. A. Brimble, G. P. Savage and M. D. McLeod,
Bioorganic and Medicinal Chemistry, 2005, 13, 4565-4575.

“Addition of 2-tert-Butyldimethylsilyloxythiophene to Activated Quinones: An Approach to Thia Analogues of Kalafungin”
M. A. Brimble, O. S. Laita and J. E. Robinson,
Tetrahedron, 2006, 62, 3021-3027.

”Synthesis of the ABC Tricyclic Fragment of the Pectenotoxins via Stereocontrolled Cyclization of a gamma-Hydroxyepoxide Appended to the AB Spiroacetal Unit”
R. Halim, M. A. Brimble and J. Merten,
Organic and Biomolecular Chemistry, 2006, 4, 1387-1399.

“A Facile Synthesis of Fused Aromatic Spiroacetals Based on the 3,4,3’,4’-Tetrahydro-2,2’-spirobis(2H-1-benzopyran) Skeleton”
M. A. Brimble, C. Flowers, M. Trzoss and K. Y. Tsang,
Tetrahedron, 2006, 62, 5883-5896.

“Synthesis of Isotopically Labelled Glycyl-L-prolyl-L-glutamic Acid (Glypromate®) and Derivatives”
P. W. R. Harris and M. A. Brimble,
Journal of Labelled Compounds and Radiopharmaceuticals, 2006, 49, 571-581.

“A Novel Bromine-Induced Ring Expansion of the Spiroimine Moiety of the Shellfish Toxin Gymnodimine”
M. A. Brimble, J. E. Robinson, J. Merten, V. Beuzenberg, M. Dragunow, P. Holland and D. Mountfort,
Synlett, 2006, 1610-1612.

“Synthesis of the Bis-Spiroacetal Moiety of the Shellfish Toxins Spirolides B and D Using an Iterative Oxidative Radical Cyclization Strategy”
K. Meilert and M. A. Brimble,
Organic and Biomolecular Chemistry, 2006, 4, 2184-2192.

Hot article and selected for front cover page

“Synthesis of N-(3-Phenylpropyl)-substituted Tricyclic ABE Ring Analogues of the Alkaloid Methyllycaconitine”
A. Lehmann, C. Brocke, D. Barker and M. A. Brimble,
European Journal of Organic Chemistry, 2006, 3205-3215.

“Synthesis of Macrocyclic Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)”
P. W. R. Harris and M. A. Brimble,
Organic and Biomolecular Chemistry, 2006, 4, 2696-2709.

“¹H and ¹³C NMR Data for C-6 Substituted 3-Azabicyclo[3.3.1]nonane-1-carboxylates”
K. Goodall, M. A. Brimble and D. Barker,
Magnetic Resonance in Chemistry, 2006, 44, 980-983.

“Synthesis of New Aza-C-disaccharides Linking 4-Deoxy-4-amino-beta-L-erythro-furanose to C-2 of D-Glucose and D-Allose”
E. Rodríguez Garcia, M. A. Brimble and P. Vogel,
European Journal of Organic Chemistry, 2006, 3845-3855.

“Synthesis of the Spiroacetal-Containing anti-Helicobacter pylori Agents CJ-12,954 and CJ-13,014”
M. A. Brimble and C. J. Bryant,
Chemical Communications, 2006, 4506-4508.

2005

“Synthesis and Pharmacological Evaluation of Glycine-Modified Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)”
M. Y. H. Lai, M. A. Brimble, D. J. Callis, P. W. R. Harris, M. S. Levi and F. Sieg,
Bioorganic and Medicinal Chemistry, 2005, 13, 533-548.

“Synthesis and Neuroprotective Activity of Analogues of Glycyl-L-prolyl-L-glutamic Acid (GPE) Modified at the alpha-Carboxylic Acid”
N. S. Trotter, M. A. Brimble, P. W. R. Harris, D. J. Callis and F. Sieg,
Bioorganic and Medicinal Chemistry, 2005, 13, 501-517.

“Synthesis and Pharmacological Evaluation of Side Chain Modified Glutamic Acid Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)”
M. A. Brimble, N. S., Trotter, P. W. R. Harris, M. S. Levi and F. Sieg,
Bioorganic and Medicinal Chemistry, 2005, 13, 519-532.

“Synthesis of Spirolactams via Diels-Alder Addition of 1,3-Butadienes to alpha-Methylenelactams”
D. Crimmins, M. Trzoss and M. A. Brimble,
Archive for Organic Chemistry (ARKIVOC), 2005, (i), 39-52.

“The First Enantioselective Total Synthesis of the anti-Helicobacter pylori Agent (+)-Spirolaxine Methyl Ether”
J. Robinson and M. A. Brimble,
Chemical Communications, 2005, 1560-1562.

“Use of Bis(aminol) Ethers derived from N-(S)-(–)-alpha-Methylbenzylamine in Reactions With Resorcinarenes and Double Mannich Reactions”
B. R. Buckley, P. C. Bulman-Page, H. Heaney, E. P Sampler, S. Carley, C. Brocke and M. A. Brimble,
Tetrahedron, 2005, 61, 5876-5888.

“Synthesis of the ABC Fragment of the Pectenotoxins”
R. Halim, M. A. Brimble and J. Merten,
Organic Letters, 2005, 7, 2659-2662.

“Synthesis of the Bis-Spiroacetal Moiety of Spirolides B and D”
K. Meilert and M. A. Brimble,
Organic Letters, 2005, 7, 3497-3500.

“Synthesis of Proline-Modified Analogues of the Neuroprotective Agent Glycyl-L-prolyl-glutamic Acid (GPE)”
P. W. R. Harris, M. A. Brimble, V. J. Muir, M. Y. H. Lai, N. S. Trotter and D. J. Callis,
Tetrahedron, 2005, 61, 10018-10035.

“Synthesis of the Phthalide-Containing anti-Helicobacter pylori agents CJ-13,015, CJ-13,102, CJ-13,103, CJ-13,104 and CJ-13,108”
M. A. Brimble, C. L. Flowers, J. K. Hutchinson, J. E. Robinson and M. Sidford,
Tetrahedron, 2005, 61, 10036-10047.

2004

“Synthesis of Cyclic Proline-Containing Peptides via Ring–Closing Metathesis”
M. A. Brimble, P. W. R. Harris and P. D. Gluckman,
Organic Letters, 2003, 5, 1847-1850.

“Radical Oxidative Cyclization of Spiroacetals to Bis-Spiroacetals: An Overview”
M. A. Brimble,
Molecules, 2004, 9, 394-404.

“Synthesis and Evaluation of Vasoconstrictor and Vasorelaxant Activity of Norbormide Isomers”
M. A. Brimble, V. J. Muir, B. Hopkins and S. Bova,
Archive for Organic Chemistry (ARKIVOC), 2004, (i), 1-11.

“A Double Alkylation – Ring Closing Metathesis Approach to Spiroimines”
M. A. Brimble and M. Trzoss,
Tetrahedron, 2004, 60, 5613-5622.

“Synthesis of Tricyclic Analogues of Methyllycaconitine Using Ring Closing Metathesis to Append a B Ring to an AE Azabicyclic Fragment”
D. Barker, M. A. Brimble, M. D. McLeod and G. P. Savage,
Organic and Biomolecular Chemistry, 2004, 2, 1659-1669.

“Synthesis of a Novel Nucleoside Based on a Spiroacetal Framework”
M. A. Brimble, J. E. Robinson, K. W. Choi and P. D. Woodgate,
Australian Journal of Chemistry, 2004, 57, 665-668.

Synthesis of Pyrrolo[3,2-b]benzofurans and Pyrrolo[3,2-b]naphthofurans via Addition of a Silyloxypyrrole to Activated Quinones”
M. A. Brimble, C. Burgess, R. Halim, M. Petersson and J. Ray,
Tetrahedron, 2004, 60, 5751-5758.

“Synthesis of Simple Analogues of Methyllycaconitine – An Efficient Method for the Preparation of the N-Substituted Anthranilate Pharmacophore”
D. Barker, M. A. Brimble and M. D. McLeod,
Tetrahedron, 2004, 60, 5953-5963.

“Application of a Double Mannich Reaction Using Bis(aminol) Ethers in the Synthesis of AE Ring Analogues of Methyllycaconitine”
C. Brocke, M. A. Brimble, D. S. H. Lin and M. D. McLeod,
Synlett, 2004, 2359-2363.

“Synthesis of the 1,6,8-Trioxadispiro[4.1.5.2]tetradec-11-ene Ring System Present in the Spirolide Family of Shellfish Toxins and its Conversion into a 1,6,8-Trioxadispiro[4.1.5.2]-tetradec-9-en-12-ol via Base-Induced Rearrangement of an Epoxide”
M. A. Brimble and D. Furkert,
Organic and Biomolecular Chemistry, 2004, 2, 3573-3583.

2003

“A Convenient Synthesis of 2-(3-Methyl-2,5-dioxopyrrolidin-1-yl)benzoic Acid”
D. Barker, M. A. Brimble and M. D. McLeod,
Synthesis, 2003, 656-658.

“Addition of Silyloxydienes to 2,6-Dibromo-1,4-benzoquinone: an Approach to Highly Oxygenated Bromonaphthoquinones for the Synthesis of Thysanone”
D. Barker, M. A. Brimble, P. Do and P. Turner,
Tetrahedron, 2003, 59, 2441-2449.

“Addition of 2-[(Trimethylsilyloxy)]furan to 2-Acetyl-1,4-benzoquinone Using Chiral Non-racemic Copper(II)-pybox Catalysts”
M. A. Brimble, M. D. K. N. Towers and P. D. Woodgate,
Archive for Organic Chemistry (ARKIVOC), 2003, (i), 43-55.

“C-Glycosylation of Oxygenated Naphthols with 3-Dimethylamino-2,3,6-trideoxy-L-arabino-hexopyranose and 3-Azido-2,3,6-trideoxy-D-arabino-hexopyranose”
M. A. Brimble, R. M. Davey, M. D. McLeod and M. Murphy,
Australian Journal of Chemistry, 2003, 56, 787-794.

“Synthesis of 3-Azido-2,3,6-trideoxy-beta-D-arabino-hexopyranosyl Pyranonaphthoquinone Analogues of Medermycin”
M. A. Brimble, R. M. Davey, M. D. McLeod and M. Murphy,
Organic and Biomolecular Chemistry, 2003, 1, 1690-1700.

“Suzuki-Miyaura Homocoupling of Naphthyl Triflates Using Bis(pinacolato)diboron: Approaches to the Biaryl Skeleton of Crisamicin A”
M. A. Brimble and M. Y. H. Lai,
Organic and Biomolecular Chemistry, 2003, 1, 2084-2095.

“Synthesis of the Spiroacetal Fragment of Broussonetine H”
M. A. Brimble, J. H. Park and C. M. Taylor,
Tetrahedron, 2003, 59, 5861-5868.

“Synthesis of Spirocyclic Imines: Key Pharmacophores in the Shellfish Toxins Spirolides and Gymnodimine”
M. A. Brimble and M. Trzoss,
Synlett, 2003, 2042-2046.

“Synthesis of Regioisomeric Analogues of Crisamicin A”
M. A. Brimble and M. Y. H. Lai,
Organic and Biomolecular Chemistry, 2003, 1, 4227-4234.

“Use of a Sonogashira-Acetylide Coupling Strategy for the Synthesis of the Aromatic Spiroketal Skeleton of gamma-Rubromycin”
M. A. Brimble, K. Y. Tsang and J. B. Bremner,
Organic Letters, 2003, 5, 4425-4427.

2002

“Stereoselective Synthesis of Deoxy Analogues of the 3C Protease Inhibitor Thysanone”
M. A. Brimble and R. J. R. Elliott,
Tetrahedron, 2002, 58, 183-189.

“A Facile Synthesis of Aryldihydropyrans Using a Sonogashira-Selenoetherification Strategy”
M. A. Brimble, G. S. Pavia and R. J. Stevenson,
Tetrahedron Letters, 2002, 43, 1735-1738.

“Synthesis of ABE Tricyclic Analogues of Methyllycaconitine Using a Wacker Oxidation – Aldol Strategy to append the B Ring to the AE Fragment“
D. Barker, M. A. Brimble, M. McLeod, G. P. Savage and D. Wong,
Journal of the Chemical Society, Perkin Transactions 1, 2002, 924-931.

“Uncatalyzed Addition of N-(tert-Butoxycarbonyl)-2-tert-butyldimethylsilyloxypyrrole to Activated Quinones”
M. A. Brimble, R. Halim and M. Petersson,
Tetrahedron Letters, 2002, 43, 4777-4780.

“Synthesis of Azido Analogue of Medermycin”
M. A. Brimble, R. M. Davey and M. D. McLeod,
Synlett, 2002, 1318-1322.

“Addition of a Chiral Non-racemic Silyloxypyrrole to an Activated 1,4-Benzoquinone”
R. Halim, M. A. Brimble and P. D. Woodgate,
Archive for Organic Chemistry (ARKIVOC), 2002, (i), 61-70.

“Application of Olefin Metathesis to the Synthesis of ABE Ring Analogues of Methyllycaconitine”
D. Barker, M. D. McLeod, M. A. Brimble and G. P. Savage,
Tetrahedron Letters, 2002, 43, 6019-6022.

“Synthesis of the C10-C22 Bis-Spiroacetal Domain of Spirolides B and D via Iterative Radical Cyclisation”
M. A. Brimble and D. P. Furkert,
Organic Letters, 2002, 4, 3655-3658.

2001

“Synthesis of the Bis-Spiroacetal Moiety of the Polyether Antibiotic CP44,161”
M. A. Brimble, P. R. Allen and H. Prabaharan,
Journal of the Chemical Society, Perkin Transactions 1, 2001, 379-389.

“A High Yielding Synthesis of Anthranilate Esters from Sterically Hindered Alcohols”
D. Barker, M. A. Brimble, M. D. McLeod and G. P. Savage,
Tetrahedron Letters, 2001, 42, 1785-1788.

“Synthesis of Arylspiroketals Related to the Papulacandins via Generation of Phthalide Oxycarbenium Ions”
M. A. Brimble, V. Caprio, A. D. Johnston and M. D. Sidford,
Synthesis, 2001, 855-862.

“Synthesis of the Novel 1,7,9-Trioxa[4.1.5.2]-tetradecane Ring System Present in the Spirolides”
M. A. Brimble, V. Caprio and D. P. Furkert,
Tetrahedron, 2001, 57, 4023-4034.

“C-Glycosylation of Tri-O-benzyl-2-deoxy-D-glucose: Synthesis of Naphthyl Substituted 3,6-Dioxabicyclo[3.2.2]nonanes”
M. A. Brimble and T. J. Brenstrum,
Journal of the Chemical Society, Perkin Transactions 1, 2001, 1612-1623.

“Synthesis of a 2-Deoxyglucosyl Analogue of Medermycin”
M. A. Brimble and T. J. Brenstrum,
Journal of the Chemical Society, Perkin Transactions 1, 2001, 1624-1634.

“C-Glycosylation of Naphthols Using Glucosyl Donors”
M. A. Brimble and T. J. Brenstrum,
Archive for Organic Chemistry (ARKIVOC), 2001, (vii), 37-48.

“Determining the Regio- and Typo-Selectivity of Calf Pregastric Lipase”
C. J. O’Connor, K. Bang, C. M. Taylor and M. A. Brimble,
Journal of Molecular Catalysis B: Enzymatic, 2001, 147-157.

“Synthesis of a Spiroacetal Intermediate for the Synthesis of the anti-Helicobacter pylori agent CJ-12,954”
M. A. Brimble, C. J. Funnell, S. Gorsuch and M. D. Sidford,
Archive for Organic Chemistry (ARKIVOC), 2001, (i), 74-87.

2000

“Reductive Thioalkylation of a Pyranonaphthoquinone”
M. A. Brimble and M. R. Nairn,
Journal of the Chemical Society, Perkin Transactions 1, 2000, 317-322.

“Synthesis of Naphthyl C-Glycosides of Rearranged Tri-O-benzyl-2-deoxy-D-glucose”
M. A. Brimble and T. J. Brenstrum,
Tetrahedron Letters, 2000, 41, 1107-1110.

“A Titanium Naphtholate Approach for the Synthesis of Analogues of Griseusin A”
M. A. Brimble, M. R. Nairn and J. S. O. Park,
Journal of the Chemical Society, Perkin Transactions 1, 2000, 697-709.

“Synthesis of a C-Glycosylpyranonaphthoquinone Related to Medermycin”
M. A. Brimble and T. J. Brenstrum,
Tetrahedron Letters, 2000, 41, 2991-2994.

“Diels-Alder Cycloaddition of Cyclopentadiene to a Bis-Naphthoquinone”
M. A. Brimble and L. J. Duncalf,
Molecules, 2000, 5, 162-166.

“Synthesis of Aryl Spiroketals Related to the Papulacandins via Allylation of Phthalides”
M. A. Brimble, V. E. Caprio, A. D. Johnston and M. H. Sidford,
Tetrahedron Letters, 2000, 41, 3955-3958.

“Regioselective Asymmetric Aminohydroxylation of Precursors to 2,3,6-Trideoxy-3-aminohexoses”
M. A. Brimble, R. M. Davey and M. D. McLeod,
Tetrahedron Letters, 2000, 41, 5141-5146.

“Diels-Alder Addition of Acyclic Dienes to Chiral Naphthoquinones”
M. A. Brimble, R. J. Elliott and J. F. McEwan,
Australian Journal of Chemistry, 2000, 53, 571-576.

“Enantioselective Synthesis of a Cyclopentannulated Kalafungin Analogue”
M. A. Brimble and J. F. McEwan,
Archive for Organic Chemistry (ARKIVOC), 2000, (i), 909-916.

“Synthesis of an Oxaspirolactone Intermediate for the Synthesis of Spirolides”
M. A. Brimble, F. A. Fares and P. Turner,
Australian Journal of Chemistry, 2000, 53, 845-851.

1999

“The Synthesis of Oxygenated Naphthyl Stannanes Possessing ortho-Methoxy Substituents for use in Stille Coupling Reactions”
M. A. Brimble  and L. J. Duncalf,
Australian Journal of Chemistry, 1999, 52, 19-29.

“Synthetic Studies towards the B,C,D,E Fragment of Antibiotic CP44,161”
P. A. Allen, M. A. Brimble, and H. Prabaharan,
Synlett, 1999, 295-298.

“Reactions of Semiquinones in Aqueous Solution.  A Comparison of One Electron Reduction of Kalafungin and Analogues With Other Semiquinones Using Pulse Radiolysis”
R. F. Anderson, M. A. Brimble, M. R. Nairn and J. E. Packer,
Journal of the Chemical Society, Perkin Transactions 2, 1999, 475-479.

“Addition of a Grignard Reagent to Bis-Spiroacetal Aldehydes: Appendage of a Tetrahydrofuran Ring”
M. A. Brimble and H. Prabaharan,
Journal of the Chemical Society, Perkin Transactions 1, 1999, 2795-2802.

“Synthesis of Analogues of Griseusin A”
M. A. Brimble, M. R. Nairn and J. Park,
Organic Letters, 1999, 1, 1459-1462.

“Deprotonation and Alkylation of 2-Methyl-4,5,6,7-tetrahydrofuro-3H-azepine”
M. A. Brimble and S. Gorsuch,
Australian Journal of Chemistry, 1999, 52, 965-969.

“Reaction of Bromonaphthofurans with Bis(pinacolato)diboron”
M. A. Brimble and F. Issa,
Australian Journal of Chemistry, 1999, 52, 1021-1028.

1998

“Synthesis and Herbicidal Activity of [3R*,5S*,6S*]-3-Benzyloxy-5-methoxy-1,7-dioxaspiro[5.5]undecane and [3R*,5S*,6S*]-3-Methoxy-5-benzyloxy-1,7-dioxaspiro-[5.5]undecane”
M. A. Brimble, R. J. Furneaux and A. D. Johnston,
Journal of Organic Chemistry, 1998, 63, 471-479.

“Synthesis of Crown Ethers Based on a Spiroacetal Framework”
M. A. Brimble and A. D. Johnston,
Journal of the Chemical Society, Perkin Transactions 1, 1998, 265-270.

“Addition of Allylsilanes to an Oxy-Stabilized Carbenium Ion on a 1,7-Dioxaspiro [5.5]-undecane Ring System”
M. A. Brimble, F. Fares and P. Turner,
Journal of the Chemical Society, Perkin Transactions 1, 1998, 677-684.

“Approaches to the D-E Ring of the Polyether Antibiotic Salinomycin Using Sharpless Asymmetric Dihydroxylation”
M. A. Brimble and H. Prabaharan,
Tetrahedron, 1998, 54, 2113-2128.

“Asymmetric Azo-ene Reactions Using the Chiral Azo-enophile Di-(–)-(1R,2S)-2-phenyl-1-cyclohexyl Diazenedicarboxylate”
M. A. Brimble and C. Y .K. Lee,
Tetrahedron Asymmetry, 1998, 9, 873-884.

“Synthesis of 7-Methoxy-3’,4’,5’,6’-tetrahydrospiro[isobenzofuran-1(3H),2’-pyran]-3-one and 5,7-Dimethoxy-3’,4’,5’,6’-tetrahydrospiro[isobenzofuran-1(3H),2’-pyran]-3-one”
M. A. Brimble and S. Chan,
Australian Journal of Chemistry, 1998, 51, 235-242.

“Asymmetric Diels-Alder Addition of Cyclopentadiene to Chiral Naphthoquinones”
M. A . Brimble, J. F. McEwan and P. Turner,
Tetrahedron Asymmetry, 1998, 9, 1239-1255.

“Asymmetric Michael Addition of 2-Trimethylsilyloxyfuran to Chiral Naphthoquinones”
M. A. Brimble, J. F. McEwan and P. Turner,
Tetrahedron Asymmetry, 1998, 9, 1257-1267.

“Addition of Cyclopentadiene and 2-Trimethylsilyloxyfuran to Quinones Bearing a Menthyl Ester Chiral Auxiliary”
M. A. Brimble, L. J. Duncalf, D. C. W. Reid and T. R. Roberts,
Tetrahedron, 1998, 54, 5363-5374.

“Synthesis of C-2 Functionalised 1,6,8-Trioxadispiro[4.1.5.3]pentadec-13-enes”
M. A. Brimble, P. R. Allen and F. Fares,
Journal of the Chemical Society, Perkin Transactions 1, 1998, 2403-2411.

“Reductive Thioalkylation of a Kalafungin Analogue”
M. A. Brimble and M. R. Nairn,
Tetrahedron Letters, 1998, 39, 4879-4882.

“Synthesis of a Dimeric Pyranonaphthoquinone via a Novel Double Furofuran Annulation Strategy”
M. A. Brimble, D. Neville and L. J. Duncalf,
Tetrahedron Letters, 1998, 39, 5647-5650.

“Synthesis of Chiral Diazanedicarboxylates”
M. A. Brimble, M. J. Duckworth and C. Y. K. Lee,
Australian Journal of Chemistry, 1998, 51, 907-913.

“Synthesis of a Novel Cage Compound via Oxidative Rearrangement of a Dihydronaphthofuran”
M. A. Brimble, R. J. R. Elliott and P. Turner,
Tetrahedron, 1998, 54, 14053-14058.

“Double Furofuran Annulation to a Bis-Naphthoquinone: An Approach to Dimeric Pyranonaphthoquinones”
M. A. Brimble, L. J. Duncalf and D. Neville,
Journal of the Chemical Society, Perkin Transactions 1, 1998, 4165-4173.

1997

“Crystal Structures of (3S*,4S*,5S*,6S*)-3,4-Epoxy-1,7-dioxaspiro[5.5]undecan-5-ol, (3R*,5S*,6S*)-1,7-Dioxaspiro[5.5]undec-3,5-diyl Diacetate and (4S*,5S*,6S*)-1,7-Dioxaspiro[5.5]undecan-4,5-diol”
M. A. Brimble, A. D. Johnston, T. W. Hambley and P. Turner,
Australian Journal of Chemistry, 1997, 50, 123-127.

“Facile Bisarylation of Aldehydes using Titanium Naphtholates”
M. A. Brimble and E. Oppen,
Synthetic Communications, 1997, 27, 989-1007.

“Synthesis of the Monomeric Unit of gamma-Actinorhodin”
M. A. Brimble, L. J. Duncalf and S. J. Phythian,
Journal of the Chemical Society, Perkin Transactions 1, 1997, 1399-1403.

“Synthesis of a New Spiroacetal Based Herbicide”
M. A. Brimble, R. J. Furneaux and A. D. Johnston,
Tetrahedron Letters, 1997, 38, 3591-3594.

“Kinetic Resolution in the Asymmetric Dihydroxylation of 1,7-Dioxaspiro[5.5]-undec-4-enes”
M. A. Brimble and A. D. Johnston,
Tetrahedron Asymmetry, 1997, 8, 1661-1676.

“Addition of Silyloxydienes to 2-Substituted 1,4-Benzoquinones and 1,4-Naphthoquinones”
M. A. Brimble and R. J. Elliott,
Tetrahedron, 1997, 53, 7715-7730.

“Synthesis of 8-Bromokalafungin as an Intermediate for the Preparation of C-Glycoside Derivatives”
M. A. Brimble, M. R. Nairn, H. Prabaharan and N. B. Walters,
Australian Journal of Chemistry, 1997, 50, 711-718.

“Use of Bis(oxazoline)-Metal Complexes as Chiral Catalysts for Asymmetric Diels-Alder Reactions Using 2-Acetyl-1,4-naphthoquinone as Dienophile”
M. A. Brimble and J. F. McEwan,
Tetrahedron Asymmetry, 1997, 8, 4069-4078.

1996

“Synthesis of (E)-1-Bromo-3-ethyl-3-pentene”
M. A. Brimble and M. K. Edmonds,
Synthetic Communications, 1996, 26, 243-251.

“Synthesis of Chiral Hydroxylated Farnesene Derivatives”
M. A. Brimble, J. A. Spicer and D. D. Rowan,
Synthesis, 1996, 116-122.

“Synthesis of Aromatic Spiroacetals”
M. A. Brimble, G. M. Horner and R. J. Stevenson,
Australian Journal of Chemistry, 1996, 49, 189-196.

“Woodward-Prevost Reactions of 1,7-Dioxaspiro[5.5]undec-4-enes”
M. A. Brimble and M. R. Nairn,
Journal of Organic Chemistry, 1996, 61, 4801-4805.

“Synthesis of Spiroketals Related to Griseusin A”
M. A. Brimble and M. R. Nairn,
Molecules, 1996, 1, 3-14.

“Synthesis of Tricyclic Aryl Spiroacetals Related to the Papulacandins”
M. A. Brimble and S. G. Robinson,
Tetrahedron, 1996, 52, 9553-9565.

1995

“Synthesis and Ene Reactions of Di-(–)-menthyl Diazenedicarboxylate”
M. A. Brimble, C. H. Heathcock and G. N. Nobin,
Tetrahedron Asymmetry, 1996, 7, 2007-2016.

“Diastereoselective Addition of 2-Trimethylsilyloxyfuran to (S)-(+)-2-(p-Tolylsulfinyl)-1,4-benzoquinone”
M. A. Brimble, L. J. Duncalf and D. C. W. Reid,
Tetrahedron Asymmetry, 1995, 6, 263-269.

“Identification of Conjugated Triene Oxidation Products of alpha-Farnesene in Appleskin”
J. M. Allen, M. A. Brimble, S. Fielder, D. D. Rowan, and J. A. Spicer,
Journal of Agriculture and Food Chemistry, 1995, 43, 2040-2045.

“Synthesis of Bis-2,5-linked Tetrahydrofurans via Iodoetherification”
M. A. Brimble and M. K. Edmonds,
Tetrahedron, 1995, 51, 9995-10012.

“Enantioselective Synthesis of the Apple Aroma Constituent 1,3,3-Trimethyl-2,7-dioxabicyclo[2.2.1]heptane via Asymmetric Dihydroxylation”
M. A. Brimble, D. D. Rowan and J. A. Spicer,
Synthesis, 1995, 1263-1266.

“Synthesis of Arizonin C1”
M. A. Brimble, S. J. Phythian and H. Prabaharan,
Journal of the Chemical Society, Perkin Transactions 1, 1995, 2855-2860.

“Synthesis of an Actinorhodin Monomer”
M. A. Brimble, L. J. Duncalf and S. J. Phythian,
Tetrahedron Letters, 1995, 36, 9202-9210.

1994

“A Short Synthesis of Deoxyfrenolicin”
M. A. Brimble and S. M. Lynds,
Journal of the Chemical Society, Perkin Transactions 1, 1994, 493-496.

“Synthesis of trans– and cis-14-Phenylsulfonyl-1,7,9-trioxadispiro[5.1.5.3]hexadecane”
M. A. Brimble and C. J. Rush,
Journal of the Chemical Society, Perkin Transactions 1, 1994, 497-500.

“Synthesis of Bicyclic Pyrazinones via Addition of Heterocyclic Amines to a Nitro-alkene”
M. A. Brimble and A. D. Johnston,
Tetrahedron, 1994, 50, 4887-4896.

“Directed ortho Metallations of Tertiary Benzamides Using Lactones as Electrophiles”
T. J. Brenstrum, M. A. Brimble and R. J. Stevenson,
Tetrahedron, 1994, 50, 4897-4904.

“Synthesis of Conjugated Trienes and Related Oxidation Products of alpha-Farnesene”
M. A. Brimble, D. D. Rowan and J. A. Spicer,
Australian Journal of Chemistry, 1994, 47, 1979-1988.

“Formal Synthesis of the Juglomycins”
M. A. Brimble and E. Ireland,
Journal of the Chemical Society, Perkin Transactions 1, 1994, 3109-3104.

“Asymmetric Dihydroxylation of alpha– and beta-Farnesene”
M. A. Brimble, D. D. Rowan and J. A. Spicer,
Tetrahedron Letters, 1994, 35, 9445-9446.

1993

“Dihydroxylation of 1,7-Dioxaspiro[5.5]undec-4-enes”
M. A. Brimble and M. R. Nairn,
Australian Journal of Chemistry, 1993, 46, 195-201.

“Allylic Amination by the Lewis-Acid-Mediated Ene Reaction of Diethyl Azodicarboxylate with Alkenes”
M. A. Brimble and C. H. Heathcock,
Journal of Organic Chemistry, 1993, 58, 5261-5263.

“Synthesis of 5-epi-Arizonin B1 and 5-epi-Arizonin C1”
M. A. Brimble and S. J. Phythian,
Tetrahedron Letters, 1993, 34, 5813-5814.

“Oxidation of alpha-Farnesene”
M. A. Brimble, D. D. Rowan and J. A. Spicer,
Australian Journal of Chemistry, 1993, 46, 1929-1939.

1992

“Synthesis of a Pyranonaphthoquinone-Spiroacetal”
M. A. Brimble and M. R. Nairn,
Journal of the Chemical Society, Perkin Transactions 1, 1992, 579-583.

“Synthesis of Deuterated Hexenols”
T. J. Brenstrum, M. A. Brimble, C. J. Rush, J. G. Shaw and D. C. W. Reid,
Journal of Labelled Compounds and Radiopharmaceuticals, 1992, 8, 629-635.

“Allylic Functionalization of the 1,7-Dioxaspiro[5.5]undec-4-ene and 1,6,8-Trioxadispiro[4.1.5.3]pentadec-13-ene Ring Systems”
M. A. Brimble, M. K. Edmonds, and G. M. Williams,
Tetrahedron, 1992, 48, 6455-6466.

“Synthesis of the Bis-Spiroacetal Moiety of 17-epi-20-Deoxysalinomycin”
M. A. Brimble and G. M. Williams,
Journal of Organic Chemistry, 1992, 57, 5818-5822.

1991

“Approaches to a Key Lactone Intermediate Required for the Synthesis of Pyranonaphthoquinone Antibiotics”
M. A. Brimble and J. A. Spicer,
Australian Journal of Chemistry, 1991, 44, 197-205.

“Highly Stereoselective syn-Hydroxylation of Spiroketals”
M. A. Brimble, M. R. Nairn and Y. Wu,
Tetrahedron Letter, 1991, 32, 4049-4050.

“Chemistry of Bis-Spiroacetals: Synthesis of cis– and trans-1-(2-Methyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-2-yl)methanol”
M. A. Brimble, G. M. Williams and R. Baker,
Journal of the Chemical Society, Perkin Transactions 1, 1991, 2221-2227.

“Synthesis of 5′-Deoxyjuglomycin A and 5′-Methoxyjuglomycin A”
M. A. Brimble, E. Ireland and S. J. Phythian,
Tetrahedron Letters, 1991, 32, 6417-6420.

1990

“Synthesis of the Insect Feeding Deterrent Peramine via Michael Addition of a Pyrrole Anion to a Nitroalkene”
M. A. Brimble and D. D. Rowan,
Journal of the Chemical Society, Perkin Transactions 1, 1990, 311-314.

“Synthesis of the Griseusin A Ring System”
M. A. Brimble and M. R. Nairn,
Journal of the Chemical Society, Perkin Transactions 1, 1990, 169-171.

“Synthesis of 5-epi-7-Deoxykalafungin and 5-epi-7-O-Methylkalafungin”
M. A Brimble and S. J. Stuart,
Journal of the Chemical Society, Perkin Transactions 1, 1990, 881-885.

“Effect of the Fungal Metabolite Peramine and Analogues on Feeding and Development of the Argentine Stem Weevil (Listronotus bonariensis)”
M. A. Brimble, D. D. Rowan and J. J. Dymock,
Journal of Chemical Ecology, 1990, 16, 1683-1695.

“The Chemistry of Bis-Spiroacetals. Synthesis of the Novel 1,7,9-Trioxadispiro-[5.1.5.3]hexadecane Ring System”
M. A. Brimble, C. J. Rush, G. M. Williams and E. N. Baker,
Journal of the Chemical Society, Perkin Transactions 1, 1990, 414-416.

“Stereocontrolled Synthesis of a Key Lactone Intermediate Required for the Synthesis of Salinomycin”
M. A. Brimble,
Australian Journal of Chemistry, 1990, 43, 1035-1046.

“Synthesis of a Functionalised Bis-Spiroacetal”
M. A. Brimble, G. M. Williams, R. Baker and M. James,
Tetrahedron Letters, 1990, 31, 3043-3046.

“Allylic Oxidation of Unsaturated Spiroketals”
M. A. Brimble, M. K. Edmonds and G. M. Williams,
Tetrahedron Letters, 1990, 31, 7509-7512.

1989

“Synthesis of the cis-3a,8b-Dihydrofuro[3,2-b]benzofuran-2(3H)-one Ring System via a Furofuran Annulation to Activated Benzoquinones”
M. A. Brimble, M. T. Brimble and J. J. Gibson,
Journal of the Chemical Society, Perkin Transactions 1, 1989, 179-184.

1988

“The Chemistry of Bis-Spiroacetals.  Synthesis of the 1,6,8-Trioxadispiro[4.1.5.3]pentadecane Ring System”
R. Baker and M. A. Brimble,
Journal of the Chemical Society, Perkin Transactions 1, 1988, 125-131.

“A Facile Synthesis of Spiroketals”
M. A. Brimble, D. L. Officer and G. M. Williams,
Tetrahedron Letters, 1988, 29, 3609-3612.

“Synthesis of 2-Methylpyrrolo[1,2-a]pyrazin-1(2H)-one”
M. A. Brimble, M. T. Brimble, R. Hodges and G. A. Lane,
Australian Journal of Chemistry, 1988, 41, 1583-1590.

“Synthesis of Peramine: An Insect Feeding Deterrent Mycotoxin from Acremonium Lolii”
M. A. Brimble and D. D. Rowan,
Journal of the Chemical Society, Chemical Communications, 1988, 978-979.

Rearrangement of a Furo[3,2-b]naphtho[2,1-d]furan to a Pyranonaphthoquinone”
M. A. Brimble, R. Hodges and S. J. Stuart,
Tetrahedron Letters, 1988, 29, 5987-5990.

1987

“1,4-Addition of 2-Trimethylsilyloxyfuran to Quinones: A Facile Route to the Furo[3,2-b]benzofuran Nucleus”
M. A. Brimble, M. T. Brimble, J. J. Gibson, R. Baker, A. A. Kee and M. J. O’Mahony,
Tetrahedron Letters, 1987, 28, 4891-4892.

1986

“Synthesis of Two Key Intermediates Required for the Construction of the Bis-Spiroacetal Moiety of epi-17-Deoxy-(O-8)-salinomycin”
R. Baker and M. A. Brimble,
Tetrahedron Letters, 1986, 27, 3311-3314.

1985

“Diastereoselective Diels-Alder Reactions of Optically-Active Vinyl Sulphoxides”
M. A. Brimble and B. R. Davis,
Tetrahedron, 1985, 41, 4965-4971.

“The Chemistry of Spiroacetals. Approaches to the Novel 1,6,8-trioxadispiro[4.1.5.3]pentadecane Ring System”
R. Baker and M. A. Brimble,
Journal of the Chemical Society, Chemical Communications, 1985, 78-80.

“Determination of the Stereochemistry of 2,2-Dimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-ene Formed by Two Sequential Cyclization Reactions Using High Field 1H NMR Spectroscopy”
R. Baker, M. A. Brimble and J. A. Robinson,
Tetrahedron Letters, 1985, 26, 2115-2118.